A Real-Life Study in Patients Newly Diagnosed with Autoimmune Hashimoto’s Thyroiditis: Analysis of Asthenia as Admission Complaint DOI Creative Commons

Ana Valea,

Mihai Costăchescu,

Mihaela Stanciu

et al.

Life, Journal Year: 2024, Volume and Issue: 14(11), P. 1380 - 1380

Published: Oct. 27, 2024

Background: Amid the large panel of autoimmune thyroid diseases, Hashimoto’s thyroiditis (HT) represents a major point across multidisciplinary daily practice. When it comes to clinical picture, particularly in regard asthenia (also described as “fatigue” or “decreased energy”), differential diagnosis is challenging, and meticulous anamnesis should be backed up by focused lab investigations. Our objective was analyze newly diagnosed patients with HT relationship presence an admission complaint. Methods: This retrospective, multi-centric, real-life study conducted secondary endocrine units (university hospitals) from July 2022 2023. The exclusion criteria were COVID-19 infection; active malignancy, etc. Results: cohort (N = 120) included group (AS, 49.2%) non-AS similar age (49.3 ± 14.7 vs. 47.1 14.8 y, p 0.426). Headache more frequent AS (35.6% 18%, 0.03). Thyroid function HT-related antibodies assays between groups show no correlation serum total cholesterol triglycerides, respectively. TSH levels did not vary among sub-groups (p 0.701). One third studied population affected hypothyroidism (TSH > 4.5 μIU/mL), being seen at higher rate (39%) (23%). Total positively correlated patients’ (r 0.180, 0.049) triglycerides 120; r 0.324, < 0.001), found only 0.246, 0.006, respectively, 0.319, 0.001). Conclusions: analysis pinpointed fact that, practice, complaint seems less indicator underlying dysfunction level against without full picture thyrotoxicosis myxoedema.

Language: Английский

A Real-Life Study in Patients Newly Diagnosed with Autoimmune Hashimoto’s Thyroiditis: Analysis of Asthenia as Admission Complaint DOI Creative Commons

Ana Valea,

Mihai Costăchescu,

Mihaela Stanciu

et al.

Life, Journal Year: 2024, Volume and Issue: 14(11), P. 1380 - 1380

Published: Oct. 27, 2024

Background: Amid the large panel of autoimmune thyroid diseases, Hashimoto’s thyroiditis (HT) represents a major point across multidisciplinary daily practice. When it comes to clinical picture, particularly in regard asthenia (also described as “fatigue” or “decreased energy”), differential diagnosis is challenging, and meticulous anamnesis should be backed up by focused lab investigations. Our objective was analyze newly diagnosed patients with HT relationship presence an admission complaint. Methods: This retrospective, multi-centric, real-life study conducted secondary endocrine units (university hospitals) from July 2022 2023. The exclusion criteria were COVID-19 infection; active malignancy, etc. Results: cohort (N = 120) included group (AS, 49.2%) non-AS similar age (49.3 ± 14.7 vs. 47.1 14.8 y, p 0.426). Headache more frequent AS (35.6% 18%, 0.03). Thyroid function HT-related antibodies assays between groups show no correlation serum total cholesterol triglycerides, respectively. TSH levels did not vary among sub-groups (p 0.701). One third studied population affected hypothyroidism (TSH > 4.5 μIU/mL), being seen at higher rate (39%) (23%). Total positively correlated patients’ (r 0.180, 0.049) triglycerides 120; r 0.324, < 0.001), found only 0.246, 0.006, respectively, 0.319, 0.001). Conclusions: analysis pinpointed fact that, practice, complaint seems less indicator underlying dysfunction level against without full picture thyrotoxicosis myxoedema.

Language: Английский

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