Clinical Course and Management of Kawasaki Disease Complicated with Duodenal Bleeding: A Two-Stage Case Review and Literature Analysis DOI
Bin Wu,

H. T. LIN

Published: May 13, 2025

Abstract Objective: To explore the clinical characteristics, diagnostic process, treatment measures, and prognosis of Kawasaki disease (KD) combined with duodenal bleeding to improve understanding this rare but serious complication. Methods: We analyzed retrospectively comprehensive data a child diagnosed KD who was admitted our hospital bleeding. In addition case, three similar instances identified through literature review were included. We summarized compared manifestations, laboratory tests, imaging endoscopic findings, strategies, prognoses. Results: All four children male, aged 2.5-11 years old, types included typical, atypical, shock syndrome(KDSS). All manifestations KD, such as fever, rash, conjunctival congestion, followed by gastrointestinal bleeding, melena, hematemesis, or hemorrhagic shock. Gastroscopy confirmed that bulb ulcer perforation source Some had intravenous immunoglobulin (IVIG) non-response severe cardiovascular complications (such coronary artery aneurysm). Treatment is mainly IVIG, antiplatelet anticoagulant drugs, proton pump inhibitors, hemostasis, surgical repair. Most have good prognosis, heart does not progress further. Conclusion: Duodenal complication requires vigilance, especially when there no response KDSS, inflammatory response. Timely evaluation act,ive supportive measures can help prognosis.

Language: Английский

Clinical Course and Management of Kawasaki Disease Complicated with Duodenal Bleeding: A Two-Stage Case Review and Literature Analysis DOI
Bin Wu,

H. T. LIN

Published: May 13, 2025

Abstract Objective: To explore the clinical characteristics, diagnostic process, treatment measures, and prognosis of Kawasaki disease (KD) combined with duodenal bleeding to improve understanding this rare but serious complication. Methods: We analyzed retrospectively comprehensive data a child diagnosed KD who was admitted our hospital bleeding. In addition case, three similar instances identified through literature review were included. We summarized compared manifestations, laboratory tests, imaging endoscopic findings, strategies, prognoses. Results: All four children male, aged 2.5-11 years old, types included typical, atypical, shock syndrome(KDSS). All manifestations KD, such as fever, rash, conjunctival congestion, followed by gastrointestinal bleeding, melena, hematemesis, or hemorrhagic shock. Gastroscopy confirmed that bulb ulcer perforation source Some had intravenous immunoglobulin (IVIG) non-response severe cardiovascular complications (such coronary artery aneurysm). Treatment is mainly IVIG, antiplatelet anticoagulant drugs, proton pump inhibitors, hemostasis, surgical repair. Most have good prognosis, heart does not progress further. Conclusion: Duodenal complication requires vigilance, especially when there no response KDSS, inflammatory response. Timely evaluation act,ive supportive measures can help prognosis.

Language: Английский

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