A pilot investigation of bovine schistosomiasis on Unguja Island, Zanzibar raises a new concern for elimination of urogenital schistosomiasis DOI Creative Commons

Shaali Ame,

Othman Juma,

Alexandra Juhász

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

Abstract Our pilot parasitological investigation of cattle, supplemented with molecular DNA characterisation encountered schistosomes, sheds first light upon bovine schistosomiasis on Unguja Island, Zanzibar. During February 2024, a total 99 cattle were examined. Of these, 47 exported animals from the Tanzanian mainland, designated for slaughter at two governmental abattoirs (Kisakasaka & Muwanda), and 52 free-grazing sampled four grazing locations within island’s North Central regions. Upon visual inspection 31 carcasses Kisakasaka adult worms, prevalence was 51.6%, whereas faecal miracidia hatching test (MHT) 80.6%. At Muwanda, only MHT used, finding much lower 12.5%. In animals, by 0.0%. Muwanda animal quarantine paddock in disrepair, inclusive large pond now acting as watering point. Here, numerous Bulinus forskalii sp. found. Whilst no snails observed to shed schistosome cercariae, xenomonitoring did detect pre-patent infection 10.8%, Schistosoma bovis firmly incriminated. Molecular schistosomes (n = 19) real-time PCR high resolution melt profiling, alongside sequencing, also identified S. although worms putative bovis-S. mattheei hybrids. Atypical intrauterine eggs noted microscopy worm pair. A broader screen 92 confirmed 3 Contrasting Pemba Zanzibar, where autochthonous transmission can occur, Island currently appears restricted imported alone. However, seminal detection bovis-mattheei hybrids, current inadequate facilities raises new concern that such hybrid may escape enter hinterland. Should this happen, surveillance control urogenital would be compromised further complicated. We therefore strongly recommend immediate repair improved maintenance facilities. Future epidemiological surveys are well-justified, not better understand full repertoire present but develop appropriate mitigating interventions.

Language: Английский

Schistosoma mattheei and zoonotic schistosomiasis DOI
J. Russell Stothard, Alexandra Juhász, Janelisa Musaya

et al.

Trends in Parasitology, Journal Year: 2025, Volume and Issue: 41(2), P. 87 - 90

Published: Jan. 6, 2025

Language: Английский

Citations

0
A pilot investigation of bovine schistosomiasis on Unguja Island, Zanzibar, raises a new concern for elimination of urogenital schistosomiasis DOI Creative Commons

Shaali Ame,

Othman Juma,

Alexandra Juhász

et al.

Parasites & Vectors, Journal Year: 2025, Volume and Issue: 18(1)

Published: March 5, 2025

Our pilot parasitological investigation of cattle, supplemented with molecular DNA characterisation encountered schistosomes, sheds first light upon bovine schistosomiasis on Unguja Island, Zanzibar. During February 2024, a total 99 cattle were examined. Of these, 47 exported animals from the Tanzanian mainland, designated for slaughter at two governmental abattoirs (Kisakasaka and Muwanda), 52 free-grazing sampled four grazing locations within island's North West-B regions. Upon visual inspection 31 carcasses Kisakasaka adult worms, prevalence was 51.6%; however, faecal miracidia hatching test (MHT) it 80.6%. At Muwanda, only MHT used, finding much lower 12.5%. In animals, by 0.0%. animal quarantine paddock in disrepair, inclusive large pond now acting as watering point. Here, numerous Bulinus forskalii sp. found. Whilst no snails observed to shed schistosome cercariae, xenomonitoring did detect pre-patent infection 10.8%, Schistosoma bovis firmly incriminated. Molecular schistosomes (n = 19) real-time polymerase chain reaction (PCR) high-resolution melt profiling, alongside sequencing, also identified S. bovis, although worms putative bovis-S. mattheei hybrids. Atypical intrauterine eggs noted microscopy worm pair. A broader screen 92 confirmed three Contrasting Pemba Zanzibar, where autochthonous transmission can occur, Island currently appears restricted imported alone. However, seminal detection bovis-mattheei hybrids, current inadequate facilities raises new concern that such hybrid may escape enter hinterland. Should this happen, surveillance control urogenital would be compromised further complicated. We therefore strongly recommend immediate repair improved maintenance facilities. Future epidemiological surveys are well justified, not better understand full repertoire present but develop appropriate mitigating interventions.

Language: Английский

Citations

0
Unexpected Zoonotic and Hybrid Schistosome Egg Excretion Patterns, Malawi, 2024 DOI
Angus M. O’Ferrall, Sekeleghe A. Kayuni, Lucas J. Cunningham

et al.

Emerging infectious diseases, Journal Year: 2025, Volume and Issue: 31(5)

Published: April 24, 2025

Two exemplary cases of mixed urogenital and intestinal schistosomiasis in Malawi show hybridizations Schistosoma mattheei with S. haematobium mansoni, indicating newly emerging genetic diversity. Complex egg excretion patterns feces expose current diagnostic gaps alert to future sampling needs for effective surveillance zoonotic schistosomiasis.

Language: Английский

Citations

0
Revealing caprine schistosomiasis and its One Health importance in Malawi: A molecular epidemiological investigation augmented with a praziquantel treatment and GPS animal tracking pilot sub-study DOI Creative Commons
Alexandra Juhász, Peter Makaula, Lucas J. Cunningham

et al.

One Health, Journal Year: 2024, Volume and Issue: 19, P. 100918 - 100918

Published: Oct. 19, 2024

Language: Английский

Citations

3
A pilot investigation of bovine schistosomiasis on Unguja Island, Zanzibar raises a new concern for elimination of urogenital schistosomiasis DOI Creative Commons

Shaali Ame,

Othman Juma,

Alexandra Juhász

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

Abstract Our pilot parasitological investigation of cattle, supplemented with molecular DNA characterisation encountered schistosomes, sheds first light upon bovine schistosomiasis on Unguja Island, Zanzibar. During February 2024, a total 99 cattle were examined. Of these, 47 exported animals from the Tanzanian mainland, designated for slaughter at two governmental abattoirs (Kisakasaka & Muwanda), and 52 free-grazing sampled four grazing locations within island’s North Central regions. Upon visual inspection 31 carcasses Kisakasaka adult worms, prevalence was 51.6%, whereas faecal miracidia hatching test (MHT) 80.6%. At Muwanda, only MHT used, finding much lower 12.5%. In animals, by 0.0%. Muwanda animal quarantine paddock in disrepair, inclusive large pond now acting as watering point. Here, numerous Bulinus forskalii sp. found. Whilst no snails observed to shed schistosome cercariae, xenomonitoring did detect pre-patent infection 10.8%, Schistosoma bovis firmly incriminated. Molecular schistosomes (n = 19) real-time PCR high resolution melt profiling, alongside sequencing, also identified S. although worms putative bovis-S. mattheei hybrids. Atypical intrauterine eggs noted microscopy worm pair. A broader screen 92 confirmed 3 Contrasting Pemba Zanzibar, where autochthonous transmission can occur, Island currently appears restricted imported alone. However, seminal detection bovis-mattheei hybrids, current inadequate facilities raises new concern that such hybrid may escape enter hinterland. Should this happen, surveillance control urogenital would be compromised further complicated. We therefore strongly recommend immediate repair improved maintenance facilities. Future epidemiological surveys are well-justified, not better understand full repertoire present but develop appropriate mitigating interventions.

Language: Английский

Citations

0