Unlocking the genomic potential of Red Sea coral probiotics DOI Creative Commons
Inês Raimundo,

Phillipe M. Rosado,

Adam R. Barno

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: March 28, 2024

Abstract The application of beneficial microorganisms for corals (BMC), both in vivo and situ, decreases the bleaching susceptibility mortality rate corals. BMC selection is typically performed via molecular biochemical assays, followed by genomic screening traits. Herein, we present an improved updated silico framework a set six putative strains. We extracted high-quality DNA from coral samples collected Red Sea PacBio sequencing. identified traits mechanisms associated with each strain as well proposed new mechanisms, such chemotaxis presence phages bioactive secondary metabolites. prophages four studied strains suggests their widespread distribution within bacteria. This newly indicates importance BMCs they can expand bacterial metabolic potential offer competitive advantage against pathogens. also detected various metabolites, terpenes, ectoines, lanthipeptides, lasso peptides. These metabolites possess antimicrobial, antifungal, antiviral, anti-inflammatory, antioxidant activities play key roles health reducing effects heat stress, high salinity, reactive oxygen species, radiation. Corals are currently facing unprecedented challenges, our revised help select more efficient use studies on microbiome rehabilitation, resilience, restoration.

Language: Английский

Building Coral Reef Resilience Through Assisted Restoration DOI
Raquel S. Peixoto, Christian R. Voolstra, Sebastian Staab

et al.

Coral reefs of the world, Journal Year: 2025, Volume and Issue: unknown, P. 235 - 243

Published: Jan. 1, 2025

Language: Английский

Citations

0
The Coral Holobiont DOI
Érika P. Santoro, Yusuf C. El‐Khaled,

Phillipe M. Rosado

et al.

Coral reefs of the world, Journal Year: 2025, Volume and Issue: unknown, P. 95 - 104

Published: Jan. 1, 2025

Language: Английский

Citations

0
Ecosystem Microbiology of Coral Reefs DOI

Kim-Isabelle Mayer,

Luigi Colin,

Christian R. Voolstra

et al.

Coral reefs of the world, Journal Year: 2025, Volume and Issue: unknown, P. 131 - 144

Published: Jan. 1, 2025

Language: Английский

Citations

0
Considerations, Ethics, and Risk Assessment for the Development and Application of Microbial-Based Therapies; Introducing a Rights-Based Framework for Reef Communities DOI
Emma F. Camp, Genevieve Wilkinson, Paige Strudwick

et al.

Coral reefs of the world, Journal Year: 2025, Volume and Issue: unknown, P. 197 - 212

Published: Jan. 1, 2025

Language: Английский

Citations

0
Phototrophic bacteria as potential probiotics for corals DOI Creative Commons
Eslam O. Osman, Neus Garcías-Bonet, Pedro Cardoso

et al.

npj Biodiversity, Journal Year: 2025, Volume and Issue: 4(1)

Published: April 29, 2025

Coral-associated microorganisms provide crucial nutritional, protective, and developmental benefits, yet many functional traits remain unexplored. Phototrophic bacteria may enhance coral nutrition reduce oxidative stress during bleaching via photosynthesis antioxidant production. Despite this potential, their role in the holobiont's energy budget heat resilience is understudied. This review explores potential of phototrophic to health under environmental stress.

Language: Английский

Citations

0
Beneficial microbes for One Health in Canada: a review of evidence and a policy proposal DOI Creative Commons
Gregor Reid, Emma Allen‐Vercoe, Kait F. Al

et al.

FACETS, Journal Year: 2025, Volume and Issue: 10, P. 1 - 32

Published: Jan. 1, 2025

The recognition that microbes are the life support system of biosphere and play a major role in health all forms provides us with unique opportunity to channel resources into utilizing them for our benefit. This policy document was prepared by assessing scientific rationale evidence application beneficial One Health. Ten recommendations made including establishment new national program creates strategies, funding, partners industries end-users make Canada self-directed global leader this transformative field. Issues covered include biotics, fecal microbiota transplant, fundamental applied research, regulatory, education system, applications pollinators, aquaculture, coral, biofertilizers, livestock, companion animals, horses, sustainability agriculture environmental management. It is hoped will provide politicians, bureaucrats, academics, representatives end users microbial products incentive appoint an expert panel develop means implement type. At time when climate change, biodiversity, long-term health, integration cultures, access home resourced nutritious food high on government agendas, proposed offers novel positively influence residents across country.

Language: Английский

Citations

0
Microbial solutions must be deployed against climate catastrophe DOI Creative Commons
Raquel S. Peixoto, Christian R. Voolstra, Lisa Y. Stein

et al.

Nature Reviews Microbiology, Journal Year: 2024, Volume and Issue: 23(1), P. 1 - 2

Published: Nov. 11, 2024

This paper is a call to action. By publishing concurrently across journals like an emergency bulletin, we are not merely making plea for awareness about climate change. Instead, demanding immediate, tangible steps that harness the power of microbiology and expertise researchers policymakers safeguard planet future generations.

Language: Английский

Citations

3
Microbial solutions must be deployed against climate catastrophe DOI Creative Commons
Raquel S. Peixoto, Christian R. Voolstra, Lisa Y. Stein

et al.

Nature Microbiology, Journal Year: 2024, Volume and Issue: 9(12), P. 3084 - 3085

Published: Nov. 11, 2024

This paper is a call to action. By publishing concurrently across journals like an emergency bulletin, we are not merely making plea for awareness about climate change. Instead, demanding immediate, tangible steps that harness the power of microbiology and expertise researchers policymakers safeguard planet future generations.

Language: Английский

Citations

3
Coracle—a machine learning framework to identify bacteria associated with continuous variables DOI Creative Commons
Sebastian Staab, Anny Cárdenas, Raquel S. Peixoto

et al.

Bioinformatics, Journal Year: 2023, Volume and Issue: 40(1)

Published: Dec. 20, 2023

Abstract Summary We present Coracle, an artificial intelligence (AI) framework that can identify associations between bacterial communities and continuous variables. Coracle uses ensemble approach of prominent feature selection methods machine learning (ML) models to features, i.e. bacteria, associated with a variable, e.g. host thermal tolerance. The results are aggregated into score incorporates the performances different ML respective importance, while also considering robustness selection. Additionally, regression coefficients provide first insights direction association. show utility by analyzing composition data (i.e. 16S rRNA Amplicon Sequence Variants, ASVs) coral tolerance standardized short-term heat stress-derived diagnostics). This analysis identified high-scoring taxa were previously found scales number performs well hundreds thousands corresponding typical size current datasets. best if run at higher taxonomic level (e.g. order or family) groups interest subsequently be ASV level. Availability implementation accessed via dedicated web server allows free simple access: http://www.micportal.org/coracle/index. underlying code is open-source available GitHub https://github.com/SebastianStaab/coracle.git.

Language: Английский

Citations

6
Validating the use of ROS-scavenging bacteria as probiotics to increase coral resilience to thermal stress DOI
Xiaoyu Tang, Qingsong Yang, Ying Zhang

et al.

Journal of Oceanology and Limnology, Journal Year: 2024, Volume and Issue: 42(4), P. 1242 - 1260

Published: June 15, 2024

Language: Английский

Citations

1