Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks DOI Creative Commons
Sudipta Sankar Bora,

Rahul Gogoi,

Madhurjya Ranjan Sharma

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: Nov. 25, 2024

Microplastics (MPs), defined as plastic particles smaller than 5 mm, are increasingly recognized environmental contaminants with potential health risks. These emerge breakdown products of larger plastics and omnipresent in marine, freshwater, terrestrial ecosystems. They primarily composed polymers such polyethylene, polypropylene, polystyrene, additives that enhance their performance. MPs also adsorb harmful chemicals like persistent organic pollutants heavy metals, posing risks to human health. Human exposure occurs mainly through ingestion inhalation, detected food products, water, even the air. have been shown accumulate gastrointestinal tract, disrupting gut microbiome, causing dysbiosis-a imbalance between beneficial bacteria. This disruption has linked various issues, including disorders, systemic inflammation, chronic diseases. Furthermore, gut-brain axis may be affected, neuroinflammatory consequences. As research continues unravel impacts MP exposure, understanding mechanisms accumulation broader implications on is crucial. review highlights effects health, emphasizing impact microbiome. We discuss connections cardiometabolic inflammatory diseases, disorders related Gut-Brain Axis. By synthesizing latest research, this work sheds light silent yet pervasive threat posed by underscores importance further studies understand fully.

Language: Английский

Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks DOI Creative Commons
Sudipta Sankar Bora,

Rahul Gogoi,

Madhurjya Ranjan Sharma

et al.

Frontiers in Cellular and Infection Microbiology, Journal Year: 2024, Volume and Issue: 14

Published: Nov. 25, 2024

Microplastics (MPs), defined as plastic particles smaller than 5 mm, are increasingly recognized environmental contaminants with potential health risks. These emerge breakdown products of larger plastics and omnipresent in marine, freshwater, terrestrial ecosystems. They primarily composed polymers such polyethylene, polypropylene, polystyrene, additives that enhance their performance. MPs also adsorb harmful chemicals like persistent organic pollutants heavy metals, posing risks to human health. Human exposure occurs mainly through ingestion inhalation, detected food products, water, even the air. have been shown accumulate gastrointestinal tract, disrupting gut microbiome, causing dysbiosis-a imbalance between beneficial bacteria. This disruption has linked various issues, including disorders, systemic inflammation, chronic diseases. Furthermore, gut-brain axis may be affected, neuroinflammatory consequences. As research continues unravel impacts MP exposure, understanding mechanisms accumulation broader implications on is crucial. review highlights effects health, emphasizing impact microbiome. We discuss connections cardiometabolic inflammatory diseases, disorders related Gut-Brain Axis. By synthesizing latest research, this work sheds light silent yet pervasive threat posed by underscores importance further studies understand fully.

Language: Английский

Citations

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