Mesenchymal stem cell application in pulmonary disease treatment with emphasis on their interaction with lung-resident immune cells DOI Creative Commons
Ali Hazrati,

Seyed Mohamad Javad Mirarefin,

Kosar Malekpour

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 8, 2024

Due to the vital importance of lungs, lung-related diseases and their control are very important. Severe inflammatory responses mediated by immune cells were among leading causes lung tissue pathology damage during COVID-19 pandemic. In addition, uncontrolled cell can lead in other infectious non-infectious diseases. It is essential a way that leads homeostasis. Immunosuppressive drugs only suppress do not affect homeostasis reactions. The therapeutic application mesenchymal stem (MSCs), addition restoring homeostasis, promote regeneration through production growth factors differentiation into cells. However, communication between MSCs after treatment pulmonary essential, investigating this help develop clinical perspective. Different studies phase showed reverse fibrosis, increase regeneration, airway remodeling, reduce tissue. proliferation potential one mechanisms effects. Furthermore, they secrete exosomes function change function. Another important mechanism harmful with innate adaptive cells, which shift system toward regulatory hemostatic responses.

Language: Английский

Pseudomonas aeruginosa Aggregates Elicit Neutrophil Swarming DOI Creative Commons

Eliana Drenkard,

C. Godfrey, Alex Hopke

et al.

iScience, Journal Year: 2025, Volume and Issue: 28(2), P. 111805 - 111805

Published: Jan. 11, 2025

Language: Английский

Citations

0

Challenges in treating patients with comorbid asthma and bronchiectasis DOI Creative Commons
Mario Cazzola, Luigino Calzetta, Maria Gabriella Matera

et al.

Respiratory Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 107957 - 107957

Published: Jan. 1, 2025

Language: Английский

Citations

0

Proteogenomic verifies targets underlying erythromycin alleviate neutrophil extracellular traps-induced inflammation DOI Creative Commons
Nan Ma, X. Liang, Q Chen

et al.

Respiratory Research, Journal Year: 2025, Volume and Issue: 26(1)

Published: April 19, 2025

Language: Английский

Citations

0

How neutrophils shape the immune response of triple-negative breast cancer: Novel therapeutic strategies targeting neutrophil extracellular traps DOI Open Access
Bing Liang, Ye Yuan,

Qianheng Jiang

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2024, Volume and Issue: 178, P. 117211 - 117211

Published: July 27, 2024

Language: Английский

Citations

3

Phillyrin inhibits oxidative stress and neutrophil extracellular trap formation through the KEAP1/NRF2 pathway in gouty arthritis DOI
Xiangfeng Xu, Yao Lu, Rong Shen

et al.

Immunologic Research, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 22, 2024

Language: Английский

Citations

0

Mesenchymal stem cell application in pulmonary disease treatment with emphasis on their interaction with lung-resident immune cells DOI Creative Commons
Ali Hazrati,

Seyed Mohamad Javad Mirarefin,

Kosar Malekpour

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 8, 2024

Due to the vital importance of lungs, lung-related diseases and their control are very important. Severe inflammatory responses mediated by immune cells were among leading causes lung tissue pathology damage during COVID-19 pandemic. In addition, uncontrolled cell can lead in other infectious non-infectious diseases. It is essential a way that leads homeostasis. Immunosuppressive drugs only suppress do not affect homeostasis reactions. The therapeutic application mesenchymal stem (MSCs), addition restoring homeostasis, promote regeneration through production growth factors differentiation into cells. However, communication between MSCs after treatment pulmonary essential, investigating this help develop clinical perspective. Different studies phase showed reverse fibrosis, increase regeneration, airway remodeling, reduce tissue. proliferation potential one mechanisms effects. Furthermore, they secrete exosomes function change function. Another important mechanism harmful with innate adaptive cells, which shift system toward regulatory hemostatic responses.

Language: Английский

Citations

0