Diagnostic approach in Giant cell arteritis
Autoimmunity Reviews,
Journal Year:
2025,
Volume and Issue:
unknown, P. 103743 - 103743
Published: Jan. 1, 2025
Language: Английский
Use of 18F‐fluorodeoxyglucose Positron Emission Tomography to Monitor Disease Activity in Patients With Giant Cell Arteritis on Tocilizumab
ACR Open Rheumatology,
Journal Year:
2025,
Volume and Issue:
7(2)
Published: Feb. 1, 2025
Objective
The
objective
of
this
study
was
to
assess
the
value
18
F‐fluorodeoxyglucose
(FDG)–
positron
emission
tomography
(PET)
scans
monitor
disease
activity
in
patients
with
giant
cell
arteritis
(GCA)
on
tocilizumab.
Methods
Patients
GCA
were
recruited
into
a
prospective
cohort
which
they
underwent
clinical,
laboratory,
and
imaging
assessments,
including
FDG‐PET.
FDG‐PET
interpreted
as
active
or
inactive
based
global
impression
by
two
independent
readers.
PET
Vascular
Activity
Score
(PETVAS)
calculated
quantify
arterial
FDG
uptake
(scale
0–27).
findings
described
tocilizumab
for
at
least
six
months.
For
established
clinical
remission,
compared
between
those
treated
versus
glucocorticoid
monotherapy.
Results
A
total
36
Five
had
symptoms,
all
cases
(PETVAS
range:
20–27).
31
remission
tocilizumab,
16
these
(52%)
across
wide
range
PETVAS
(range
11–27).
There
no
associations
during
historical
features
longitudinal
outcomes,
relapse
risk
angiographic
progression
disease.
significantly
lower
an
additional
12
monotherapy
vs
24;
P
=
0.02).
Conclusion
has
limited
guide
management
decisions
inform
prognosis
when
obtained
Compared
monotherapy,
reduces,
but
often
does
not
eliminate,
vascular
inflammation
GCA.
Language: Английский
Artérite à cellules géantes : place de la chirurgie dans la prise en charge des complications vasculaires
Hélène Greigert,
No information about this author
Camil-Cassien Bamdé,
No information about this author
André Ramon
No information about this author
et al.
Revue du Rhumatisme,
Journal Year:
2024,
Volume and Issue:
92(1), P. 111 - 119
Published: July 30, 2024
An overview of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in giant cell arteritis
Frontiers in Medicine,
Journal Year:
2024,
Volume and Issue:
11
Published: Oct. 14, 2024
PET/CT
is
an
imaging
modality
that
increasingly
being
used
to
diagnose
large-vessel
vasculitis.
In
the
case
of
giant
cell
arteritis,
it
was
first
demonstrate
inflammation
walls
large
arterial
trunks
such
as
aorta
and
its
main
branches,
showing
aortic
involvement
common
in
this
vasculitis
associated
with
occurrence
complications
aneurysms.
More
recently,
advent
digital
PET/CT,
study
cranial
arteries
(i.e.,
temporal,
occipital,
maxillary
vertebral
arteries)
has
become
possible,
further
increasing
diagnostic
interest
examination
for
diagnosis
GCA.
Despite
these
advantages,
there
are
still
limitations
questions
regarding
use
especially
follow-up
The
aim
review
take
stock
currently
available
data
on
GCA
follow-up.
Language: Английский