Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation DOI Creative Commons

Nathalia Silva Dutra Alves,

Gustavo Roncoli Reigado,

Mayara Santos

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 12, 2025

Significant progress has been made in regenerative medicine for skin repair and rejuvenation. This review examines core technologies including stem cell therapy, bioengineered substitutes, platelet-rich plasma (PRP), exosome-based therapies, gene editing techniques like CRISPR. These methods hold promise treating a range of conditions, from chronic wounds burns to age-related changes genetic disorders. Challenges remain optimizing these therapies broader accessibility ensuring long-term safety efficacy.

Language: Английский

Use of Exosomes for Cosmetics Applications DOI Creative Commons
Luis Jesús Villarreal-Gómez,

Sergio Origel-Lucio,

Daniela Alejandra Hernández-Hernández

et al.

Cosmetics, Journal Year: 2025, Volume and Issue: 12(1), P. 9 - 9

Published: Jan. 13, 2025

This study addresses a significant gap in the clinical validation and standardization of exosome-based applications within domains cosmetics regenerative medicine. Despite offering thorough overview potential therapeutic benefits underlying mechanisms exosomes, manuscript underscores several unresolved challenges, including paucity evidence, regulatory barriers, inconsistencies standardization, incomplete mechanistic understanding. The primary aim this research is to conduct systematic comprehensive review existing studies on exosomes skincare. To achieve this, literature was performed, drawing major medical database PubMed. approach facilitated collection meta-analysis relevant data, ensuring rigorous assessment recent advancements exosome research. main outcomes highlight multifaceted roles promoting skin rejuvenation mitigating signs aging. Specific discussed include pigmentation correction, wound healing, tissue repair, innovative delivery mechanisms. Moreover, examines emerging plastic surgery Challenges limitations, such as constraints, hurdles, need for further validation, are critically analyzed, providing framework future directions.

Language: Английский

Citations

0
Advances in regenerative medicine-based approaches for skin regeneration and rejuvenation DOI Creative Commons

Nathalia Silva Dutra Alves,

Gustavo Roncoli Reigado,

Mayara Santos

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: Feb. 12, 2025

Significant progress has been made in regenerative medicine for skin repair and rejuvenation. This review examines core technologies including stem cell therapy, bioengineered substitutes, platelet-rich plasma (PRP), exosome-based therapies, gene editing techniques like CRISPR. These methods hold promise treating a range of conditions, from chronic wounds burns to age-related changes genetic disorders. Challenges remain optimizing these therapies broader accessibility ensuring long-term safety efficacy.

Language: Английский

Citations

0