Hedyotis diffusa alleviate aflatoxin B1-induced liver injury in ducks by mediating Nrf2 signaling pathway DOI Creative Commons
Pengpeng Wang, Yingli Wang, Tianyi Feng

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2022, Volume and Issue: 249, P. 114339 - 114339

Published: Dec. 9, 2022

Aflatoxin B1 (AFB1), the most harmful aflatoxins, is a frequent contamination in feed and food items, raising global concerns animal production human public health. Also, AFB1 induces oxidative stress, cytotoxicity, mutations, DNA lesions through its metabolic transformation into aflatoxin B1–8,9-epoxide (AFBO) by cytochrome P450 (CYP450). Hedyotis diffusa (HD) traditional Chinese herbal medicine known for multiple pharmacological activities, including antioxidant, anti-inflammatory, immunomodulatory. Yet, influence of HD on AFB1-induced liver injury ducks still unknown. Here, we investigated whether positively affects ducks. Results revealed that I) caused significant changes serum biochemical indices decreased growth performance (such as ALT, AST, ALP, TP, ALB, final body weight, weight gain), whereas supplementation at 200 mg/kg mitigated these alterations. II) alleviated hepatic histopathological index induced III) significantly attenuated measured increased antioxidant enzyme activities such SOD, GPx, T-AOC MDA levels. Furthermore, reduced level AFB1-DNA adduct duck liver. IV) promoted transcriptional expression NF-E2-related nuclear factor 2 (Nrf2) associated genes, heme oxygenase 1 (HO-1), NAD(P)H dehydrogenase quinone (NQO1), glutamate-cysteine ligase catalytic (GCLC). In conclusion, results demonstrated could activate Nrf2 pathway to reduce hepatotoxicity driven AFB1. This finding also provides theoretical data support deeper understanding toxic mechanisms prevention.

Language: Английский

Evaluation of some artificial food preservatives and natural plant extracts as antimicrobial agents for safety DOI Creative Commons

Jianrong Shi,

Jian‐Hong Xu, Xin Liu

et al.

Discover Food, Journal Year: 2024, Volume and Issue: 4(1)

Published: Sept. 6, 2024

Language: Английский

Citations

6
The Effects of Encapsulation on the In Vitro Anti-Clostridial Activity of Olive Mill Wastewater Polyphenolic Extracts: A Promising Strategy to Limit Microbial Growth in Food Systems DOI Creative Commons
Rossana Roila, Sara Primavilla, David Ranucci

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(7), P. 1441 - 1441

Published: March 23, 2024

Despite the technologies applied to food production, microbial contamination and chemical deterioration are still matters of great concern. In order limit these phenomena, new natural approaches should be applied. this context, present study aimed assess antioxidant anti-Clostridial effects two different polyphenolic extracts derived from olive mill vegetation water, one liquid (LE) encapsulated (EE). The have been preliminary characterized using Liquid Chromatography Quadrupole Time-Of Flight spectrometry. Oxygen Radical Absorbance Capacity method was used determine capacity, registering a higher value for EE compared that LE (3256 ± 85 2446 13 µgTE/g, respectively). antibacterial activity against C. perfringens, botulinum difficile studied by agar well diffusion method, MIC MBC determination time-kill test. results confirm able growth, albeit with minor when phenolic compounds encapsulated. Further studies needed evaluate possible application in systems.

Language: Английский

Citations

5
Recent applications of natural bioactive compounds from Piper betle (L.) leaves in food preservation DOI

Viet Thanh Tran,

Tran B. Nguyen,

Ha Chi Nguyen

et al.

Food Control, Journal Year: 2023, Volume and Issue: 154, P. 110026 - 110026

Published: Aug. 7, 2023

Language: Английский

Citations

13
Impact of food-relevant conditions and food matrix on the efficacy of prenylated isoflavonoids glabridin and 6,8-diprenylgenistein as potential natural preservatives against Listeria monocytogenes DOI Creative Commons
Alberto Bombelli, Carla Araya‐Cloutier, Jean‐Paul Vincken

et al.

International Journal of Food Microbiology, Journal Year: 2023, Volume and Issue: 390, P. 110109 - 110109

Published: Feb. 3, 2023

Prenylated isoflavonoids can be extracted from plants of the Leguminosae/Fabaceae family and have shown remarkable antimicrobial activity against Gram-positive food-borne pathogens, such as Listeria monocytogenes. Promising candidates this class compounds are glabridin 6,8-diprenylgenistein. This research aimed to investigate potential 6,8-diprenylgenistein food preservatives L. Their was tested in vitro at various conditions relevant for application, different temperatures (from 10 °C 37 °C), pH (5 7.2), presence or absence oxygen. The minimum inhibitory concentrations were between 0.8 12.5 μg/mL all conditions. Growth activities similar compared higher temperatures, although bactericidal decreased when temperature decreased. Notably, lower (pH 5) increased growth compounds, especially Furthermore, efficacies anaerobically aerobically Glabridin showed a more stable Therefore, we further determined efficacy monocytogenes on fresh-cut cantaloupe °C. In these conditions, 50, 100 250 μg/g significantly reduced control, resulting average >1 Log CFU/g difference after 4 days control. Our results underscored importance considering matrix assessing novel antimicrobials. Overall, study highlights prenylated naturally derived preservatives.

Language: Английский

Citations

12
Evaluation of the antibacterial activity of Elsholtzia ciliate essential oil against halitosis-related Fusobacterium nucleatum and Porphyromonas gingivalis DOI Creative Commons
Fengjiao Li, Chuandong Wang, Jing Xu

et al.

Frontiers in Microbiology, Journal Year: 2023, Volume and Issue: 14

Published: Aug. 7, 2023

The broad-spectrum antimicrobial activity of Elsholtzia ciliate essential oil (ECO) has been previously reported, but its effectiveness against halitosis-causing bacteria such as Fusobacterium nucleatum and Porphyromonas gingivalis is not well understood. In this study, we investigated the bacteriostatic ECO planktonic cells biofilms F. P. gingivalis, ability to inhibit bacterial metabolism production volatile sulfur compounds (VSCs) at sub-lethal concentrations. Our findings revealed that exhibited comparable activities chlorhexidine these oral bacteria. Treatment with significantly reduced VSCs, including hydrogen sulfide, dimethyl disulfide, methanethiol, which are major contributors bad breath. As chemical components ECO, carvacrol, p-cymene, phellandrene, were demonstrated in vitro inhibitory effects on their combined use showed synergistic additive effects, suggesting overall derived from cumulative or effect multiple active components. was found have a destructive cell membrane by examining morphology permeability. Furthermore, application induced significant changes composition saliva-derived biofilm, resulting elimination species contribute halitosis, Fusobacterium, Porphyromonas, Prevotella. These results provide experimental evidence for potential clinical applications ECOs prevention treatment halitosis.

Language: Английский

Citations

11
Chemical profiles and bioactivities of polyphenolic extracts of Lavandula stoechas L., Artemisia dracunculus L. and Ocimum basilicum L. DOI Creative Commons
Beatriz Silva, Vasco Cadavez, Cristina Caleja

et al.

Food Chemistry, Journal Year: 2024, Volume and Issue: 451, P. 139308 - 139308

Published: April 15, 2024

This study assessed the chemical profiles and bioactivities of infusions, decoctions hydroethanolic extracts tarragon, basil French lavender. The were chemically characterised (HPLC-DAD-ESI/MS) their evaluated in vitro. All revealed antimicrobial, antifungal antioxidant properties. lavender showed higher total phenolic content, regardless extraction method used, antitumour capacities, but no anti-inflammatory action. two tarragon power. Thus, may be considered for inclusion foods, as preservatives or functional ingredients. Nonetheless, further studies must conducted to evaluate pharmacokinetic parameters bioactive compounds.

Language: Английский

Citations

4
Antifungal efficiency and mechanisms of ethyl ferulate against postharvest pathogens DOI
Chang Shu, Xiuxiu Sun, Jiankang Cao

et al.

International Journal of Food Microbiology, Journal Year: 2024, Volume and Issue: 417, P. 110710 - 110710

Published: April 21, 2024

Language: Английский

Citations

4
Therapeutic potential of Chromolaena odorata, Vernonia amygdalina, and Cymbopogon citratus against pathogenic Bacteria DOI Creative Commons

Udensi Justina Ugochi,

Anyanwu Charles Obinna,

Emedoh Andrew Emeka

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Jan. 2, 2025

Language: Английский

Citations

0
Citric acid plays a dual ‘synergistic/antagonistic’ role with antibiotics in multidrug-resistant Salmonella Typhimurium DOI Creative Commons

Bismi Phasaludeen,

Dania Mustafa Darwich,

Greeshma Bharathan

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 105843 - 105843

Published: Jan. 1, 2025

Language: Английский

Citations

0
Efficacy of Phage Application in Modulating Raw Milk Microbiota: Targeting Escherichia coli, Pseudomonas fluorescens, and Lactiplantibacillus plantarum DOI
Esra Ekiz, Kubra Guven, Emine Kübra Tayyarcan

et al.

Food Control, Journal Year: 2025, Volume and Issue: unknown, P. 111166 - 111166

Published: Jan. 1, 2025

Language: Английский

Citations

0