Unveiling the Genomic Features and Biocontrol Potential of Trichoderma hamatum Against Root Rot Pathogens

Journal of Fungi, Journal Year: 2025, Volume and Issue: 11(2), P. 126 - 126

Published: Feb. 8, 2025

Fusarium species are among the most significant pathogens causing root rot in Panax notoginseng. In this study, a strain of Trichoderma hamatum was isolated from rhizosphere soil P. notoginseng and subjected to whole-genome sequencing. Plate confrontation experiments were conducted investigate antagonistic effects T. against oxysporum, solani, acutatum, primary rot. Whole-genome sequencing revealed 10,774 predicted genes hamatum, which 454 associated with carbohydrate-active enzymes (CAZymes) involved fungal cell wall degradation. Additionally, 11 biosynthetic gene clusters (BGCs) antimicrobial production identified, highlighting biocontrol potential hamatum. plate experiments, showed substantial inhibition rates 68.07%, 70.63%, 66.12% F. respectively. Scanning electron microscopy suggested hyperparasitism characterized by spore that adhered pathogen, thereby inhibiting its growth. These findings provide theoretical foundation enhance understanding biological control mechanisms supporting applications sustainable agriculture.

Language: Английский

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Decoding Rhizoctonia spp. in-depth genomic analysis, pathogenic mechanisms, and host interactions

Phytopathology Research, Journal Year: 2025, Volume and Issue: 7(1)

Published: March 4, 2025

Abstract This review investigates Rhizoctonia species, highlighting their taxonomy, genetic diversity, and pathogenic mechanisms that pose significant challenges to agriculture horticulture. spp. are complex pathogens capable of infecting a wide range hosts through sophisticated infection strategies developing resistance commonly used fungicides, threatening global food security. Key findings reveal the necessity integrated disease management combine cultural practices, biological control, chemical applications, deployment resistant cultivars manage these effectively. The also emphasizes growing impact climate change on pathogen dynamics prevalence, stressing need for flexible innovative approaches. A multidisciplinary approach, integrating insights from plant pathology, genetics, soil science, is essential address -related diseases comprehensively. strategy not only aims reduce immediate crop health yield but enhances long-term sustainability resilience agricultural horticultural systems amid evolving environmental conditions, contributing efforts in maintaining

Language: Английский

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Microbial Biotoxins in Biotechnological Applications for Plant Disease and Pest Management

Published: Jan. 1, 2025

Language: Английский

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Discovery of a novel fungal Tc toxin complex and a functional myco- serpin via a unique two-by-two comparative genomics pipeline

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Background Fungi have been a rich source of pharmaceuticals such as antibiotics, immunosuppressants, and cholesterol-lowering drugs; however, their therapeutic potential remains largely untapped due to difficulties in culturing elucidating the genetic basis beneficial traits. contain 'cryptic' genes that are expressed under certain, often obscure, growth conditions can produce complex compounds difficult synthesize economically. Developments genome sequencing DNA-synthesis technologies offer new opportunities using biotechnological techniques, accurately identifying useful novel genes, prerequisite for approaches, challenging. Results We present ‘two-by-two’ comparative genomics pipeline comprehensive gene analysis selected fungal groups, enabling more confident identification unique across analyzed species. The approach compares sets from two strains same species with those different or families within order. Self-clustering orthologs provide higher confidence species-specific proteins help reduce noise low-quality assemblies prediction errors. validated our method on well-studied group fungi, discovering first functional myco-serpin an undescribed Tc toxin complex. Using knockout approach, we implicated both proteins’ roles insect host infection process this entomopathogenic Conclusions Elucidating underlying traits fungi presents significant challenges, relatively aspects lifestyles. Our two-by-two offers broad applications mining bioprospecting exemplified study by discovery myco-serpin. identified high sequence identity serpin other pathogenic strains, including known infect humans. Furthermore, be adapted organisms architectures similar fungi.

Language: Английский

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Multifunctionality and Diversity of Antagonistic Potential Fungi as Biocontrol Agent

Published: Jan. 1, 2025

Language: Английский

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