Ellagic acid ameliorates alcohol-induced cognitive and social dysfunction through the gut microbiota-mediated CCL21-CCR7 axis DOI

Hongbo Zhang,

Min Luo,

Yinuo Li

et al.

Food & Function, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

EA enhanced the abundance of beneficial bacteria as well their derived metabolites, thereby inhibiting chronic alcohol-induced neuroinflammation via regulation gut microbiota-mediated CCL21-CCR7 axis, ultimately ameliorating AICSD.

Language: Английский

Neurolaw: Revisiting Huberty v. McDonald’s through the Lens of Nutritional Criminology and Food Crime DOI Creative Commons

Alan Logan,

Jeffrey J. Nicholson,

Stephen J. Schoenthaler

et al.

Laws, Journal Year: 2024, Volume and Issue: 13(2), P. 17 - 17

Published: March 21, 2024

Recent studies have illuminated the potential harms associated with ultra-processed foods, including poor mental health, aggression, and antisocial behavior. At same time, human gut microbiome has emerged as an important contributor to cognition behavior, disrupting concepts of biopsychosocial ‘self’ raising questions related free will. Since is undeniably connected dietary patterns components, topics nutrition microbes are heightened interest neuroscience psychiatry. Research spanning epidemiology, mechanistic bench science, intervention trials brought legitimacy nutritional criminology idea that relevance criminal justice system. The individual community-level relationships between behavior also salient torts relatively new field food crime—that which examines vast harms, grand-scale non-communicable diseases behavioral outcomes, caused by manufacturers, distributors, marketers products. Here in this essay, we will synthesize various strands research, reflecting emergent using a notable case straddled both neurolaw crime, Huberty v. McDonald’s (1987). It our contention legalome—microbiome omics science applied forensics—will play increasing role 21st-century courtroom discourse, policy, decision-making.

Language: Английский

Citations

7

Beyond Auto-Brewery: Why Dysbiosis and the Legalome Matter to Forensic and Legal Psychology DOI Creative Commons

Alan Logan,

Susan L. Prescott, Erica M. LaFata

et al.

Laws, Journal Year: 2024, Volume and Issue: 13(4), P. 46 - 46

Published: July 11, 2024

International studies have linked the consumption of ultra-processed foods with a variety non-communicable diseases. Included in this growing body research is evidence linking to mental disorders, aggression, and antisocial behavior. Although idea that dietary patterns various nutrients or additives can influence brain behavior has long history criminology, absence plausible mechanisms convincing intervention trials, topic was mostly excluded from mainstream discourse. The emergence across nutritional neuroscience psychology/psychiatry, combined mechanistic bench science, human provided support epidemiological findings, legitimacy concept criminology. Among emergent research, microbiome sciences illuminated pathways socioeconomic environmental factors, including foods, aggression Here review, we examine burgeoning related food addiction, explore its relevance criminal justice spectrum—from prevention intervention—and courtroom considerations diminished capacity. We use auto-brewery syndrome as an example intersecting diet gut science been used refute mens rea charges. legalome—microbiome omics applied forensic legal psychology—appears set emerge important consideration matters law, justice.

Language: Английский

Citations

5

The Legalome: Microbiology, Omics and Criminal Justice DOI Creative Commons
Alan C. Logan, Pragya Mishra, Susan L. Prescott

et al.

Microbial Biotechnology, Journal Year: 2025, Volume and Issue: 18(3)

Published: March 1, 2025

ABSTRACT Advances in neuromicrobiology and related omics technologies have reinforced the idea that unseen microbes play critical roles human cognition behaviour. Included this research is evidence indicating gut microbes, through direct indirect pathways, can influence aggression, anger, irritability antisocial Moreover, manufacture chemicals are known to compromise cognition. For example, recent court decisions United States Europe acknowledge produce high levels of ethanol, without consumption alcohol by defendants. The dismissal driving while intoxicated charges these cases—so‐called auto‐brewery syndrome—highlights way which microbiome knowledge will enhance precision, objectivity fairness our legal systems. Here opinion essay, we introduce concept ‘legalome’—the application science forensic psychiatry criminal law. We argue rapid pace microbial discoveries, including those challenge ideas free moral responsibility, necessitate a reconsideration traditional doctrines justifications retributive punishment. implications extend beyond courtroom, challenging us reconsider how environmental factors—from diet socioeconomic conditions—might shape preventative rehabilitative efforts their effects on microbiome.

Language: Английский

Citations

0

The role of microbiome in gut-brain-axis dysbiosis causing depression: From mechanisms to treatment DOI

Junqiao Mi,

Julia Morys, Marta Nowacka-Chmielewska

et al.

International review of neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

0

Therapeutic potential of faecal microbiota transplantation for alcohol use disorder, a narrative synthesis DOI

JOHN M. DOCHERTY

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2025, Volume and Issue: unknown, P. 111354 - 111354

Published: April 1, 2025

Language: Английский

Citations

0

Prebiotic inulin alleviates anxiety and depression-like behavior in alcohol withdrawal mice by modulating the gut microbiota and 5-HT metabolism DOI
Kuan Li, Wei Wei, Chongchong Xu

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: 135, P. 156181 - 156181

Published: Oct. 28, 2024

Language: Английский

Citations

2

Sleep deprivation-induced shifts in gut microbiota: Implications for neurological disorders DOI
Nitu L. Wankhede, Mayur B. Kale,

Ashishkumar Kyada

et al.

Neuroscience, Journal Year: 2024, Volume and Issue: 565, P. 99 - 116

Published: Nov. 30, 2024

Language: Английский

Citations

2

Homicide or Happiness: Did Folate Fortification and Public Health Campaigns Influence Homicide Rates and the Great American Crime Decline? DOI Creative Commons
Stephen J. Schoenthaler, Susan L. Prescott,

Alan Logan

et al.

Nutrients, Journal Year: 2024, Volume and Issue: 16(7), P. 1075 - 1075

Published: April 6, 2024

The last several years have witnessed a remarkable growth in research directed at nutrition and behavior, with increased interest the field of nutritional criminology. It is becoming clear that dietary patterns specific nutrients play an important role cognition including those related to aggression, violence, antisocial activity. Included this expanding knowledge base recognition folate, through multiple pathways, enzymatic reactions gut microbiome ecology, plays critical central nervous system functioning. These mechanistic advances allow for retrospective analysis topic remains unexplained—the sudden unpredicted drop homicide other violent crime rates United States nations 1990s. Here, we revisit marked reduction lens coincident public health campaign (and subsequent mandatory fortification) increase folic acid intake. Based on objectively measured blood folate levels National Health Nutrition Examination Surveys, there little doubt tissue dramatic rise national level from 1988 2000. Drawing accumulated emerging neurobehavioral aspects it our contention relatively massive may contributed reductions States.

Language: Английский

Citations

1

Nutritional Strategies in Major Depression Disorder: From Ketogenic Diet to Modulation of the Microbiota-Gut-Brain Axis DOI
Ali Nikdasti,

Elaheh Sadat Khodadadi,

Felora Ferdosi

et al.

Molecular Neurobiology, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 28, 2024

Language: Английский

Citations

1

Cultured fecal microbial community and its impact as fecal microbiota transplantation treatment in mice gut inflammation DOI Creative Commons
Vineet Singh, Seung-Dae Choi, Kanika Mahra

et al.

Applied Microbiology and Biotechnology, Journal Year: 2024, Volume and Issue: 108(1)

Published: Sept. 13, 2024

Language: Английский

Citations

1