Probiotic Consortium from Poultry Strains for Supporting Gut Immunity Against Pathogens DOI

Guldana Boranbayeva,

Zhanar Tekebayeva, Aslan Temirkhanov

et al.

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: unknown, P. 107584 - 107584

Published: April 1, 2025

Language: Английский

Exoproteomic Evidence for BcTSPO‐Mediated Regulation of Virulence Factors in Bacillus cereus DOI Creative Commons
Catherine Duport, Jean Armengaud

PROTEOMICS, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Bacillus cereus translocator protein (BcTSPO) is a transmembrane that plays regulatory role in various phenotypes, potentially including its virulence. Given the exoproteome major determinant of B. virulence, particularly during late stages active growth, analysis crucial for understanding functions BcTSPO. In this study, we conducted comparative exoproteomes and cellular proteomes Δtspo mutant wild-type ATCC 14579 strain exponential early stationary growth phases. Shotgun proteomics revealed absence BcTSPO significantly depleted secreted virulence factors, HBL, NHE, CytK enterotoxins. Interestingly, cholesterol-dependent cereolysin O (CLO) was more abundant exoproteome, indicating distinct mechanism. The proteome further confirmed positively regulates, likely indirectly, synthesis enterotoxins negatively regulates production CLO. Additionally, enriched moonlighting proteins, reflecting impact on metabolism stress responses. Overall, these findings highlight critical shaping composition both proteome, with significant implications cereus.

Language: Английский

Citations

0
Genetic origins of microbial virulence DOI
Subhasish Chatterjee

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 153 - 177

Published: Jan. 1, 2025

Language: Английский

Citations

0
Discovery of novel seven-membered ring derivatives of ONC212 as caseinolytic protease P protein activators using the ring expansion strategy: Rational design, synthesis, and antibacterial evaluation DOI

X. FU,

Yu Peng,

Zhou‐Qing Long

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141866 - 141866

Published: March 1, 2025

Language: Английский

Citations

0
Targeting quorum sensing in Pseudomonas aeruginosa with high-affinity inhibitors: A high-throughput screening and in-silico analysis DOI
Sidra Abbas, Shama Mujawar, Azra Yasmin

et al.

Computational Biology and Chemistry, Journal Year: 2025, Volume and Issue: 117, P. 108419 - 108419

Published: March 11, 2025

Language: Английский

Citations

0
Virulence Is More than Adhesion and Invasion Ability, an In Vitro Cell Infection Assay of Bovine Mycoplasma spp. DOI Creative Commons
Elhem Yacoub, Daniel Kos,

Murray Jelinski

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 632 - 632

Published: March 11, 2025

Mycoplasma bovis is the most common mycoplasma associated with cattle diseases worldwide. However, other seemingly less virulent spp. such as M. bovigenitalium and bovirhinis have also been mycoplasmosis. The study objective was to compare adhesion cellular invasion characteristics of these bovine using Madin–Darby Bovine Kidney (MDBK) epithelial cells. MDBK cells were separately infected 12 strains one strain each bovirhinis. Following infection, a gentamicin protection assay performed lysed at 6 54 h post-infection. cell lysates cultured for qPCR used estimate average number bacterial that (Myc/Cell ratio). Confocal electron microscopy studies mNeonGreen performed. All 14 multiplied within cells, finding confirmed by strain. Unexpectedly, strains, obtained from diseased asymptomatic bison, had lower Myc/Cell ratios than strains. These findings suggest ability mycoplasmas invade replicate host does not account differences in virulence between species.

Language: Английский

Citations

0
Bioguided isolation, identification and activity evaluation of antibacterial compounds from Combretum rhodanthum Engl. & Diels DOI

Joseph Mbaku Ngoumou,

Vincent Ngouana, Boniface Pone Kamdem

et al.

South African Journal of Botany, Journal Year: 2025, Volume and Issue: 180, P. 236 - 253

Published: March 13, 2025

Language: Английский

Citations

0
Ecotin as a novel virulence factor: Enhancing Edwardsiella piscicida survival and pathogenicity DOI
Xinyu Bai, Yan Wang,

Qingjian Fang

et al.

Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742428 - 742428

Published: March 1, 2025

Language: Английский

Citations

0
A One Health approach to the prevention, control, and management of leptospirosis: a scoping review DOI Creative Commons
Khristine L. Sandoval,

Kristel Joy S. Cada,

Rodel Victor D. Dimasin

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 22(1)

Published: March 18, 2025

Language: Английский

Citations

0
Recent development of copper, silver and their bimetallic nanoparticles: Next-generation antibacterial agents through photocatalysis activity DOI

Jing Chang Chia,

Chin Wei Lai,

Joon Ching Juan

et al.

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 72, P. 107541 - 107541

Published: March 30, 2025

Language: Английский

Citations

0
Effectiveness of a CuZnNi alloy in preventing microbial growth and biofilm architecture DOI Creative Commons
Guilherme Gonçalves Guerini, M. Suenaga, Vitor Gonçalves Vital

et al.

Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0