Evaluation of the Phytochemical Composition and Antibacterial Efficacy of Momordica balsamina and Luffa aegyptiaca Leaf Extracts DOI Creative Commons

Muhammad Shehu Giwa,

Basira Ibrahim,

F.M. Musa

et al.

Published: Jan. 17, 2025

Article Evaluation of the Phytochemical Composition and Antibacterial Efficacy Momordica balsamina Luffa aegyptiaca Leaf Extracts Muhammad Shehu Giwa 1, Basira Ibrahim Fatima Musa Emad M. Abdallah 2,3,* 1 Department biological sciences, Faculty Life Sciences, College Science, Computing Engineering, Kaduna State University, 800283, Nigeria 2 Biology, Qassim 51452, Saudi Arabia 3 Health INTI International Nilai 71800, Negeri Sembilan, Malaysia * Correspondence: [email protected] Received: 21 September 2024; Revised: 7 October Accepted: November Published: 17 January 2025 Abstract: The current study evaluated antibacterial activities methanol leaf extracts from aegyptica against clinical isolates Staphylococcus aureus, Salmonella typhi, Escherichia coli. analysis revealed presence various bioactive compounds, including alkaloids, flavonoids, tannins, while anthraquinones were absent. Both demonstrated significant activity, particularly Gram-negative bacteria (S. typhi), with minimum inhibitory concentrations (MIC) as low 12.5 mg/mL bactericidal (MBC) 25 for balsamina, MIC MBC 50 L. aegyptica. These findings suggest that these plants have potential sources agents, warranting further pharmaceutical investigation.

Language: Английский

Evaluation of the Phytochemical Composition and Antibacterial Efficacy of Momordica balsamina and Luffa aegyptiaca Leaf Extracts DOI Creative Commons

Muhammad Shehu Giwa,

Basira Ibrahim,

F.M. Musa

et al.

Published: Jan. 17, 2025

Article Evaluation of the Phytochemical Composition and Antibacterial Efficacy Momordica balsamina Luffa aegyptiaca Leaf Extracts Muhammad Shehu Giwa 1, Basira Ibrahim Fatima Musa Emad M. Abdallah 2,3,* 1 Department biological sciences, Faculty Life Sciences, College Science, Computing Engineering, Kaduna State University, 800283, Nigeria 2 Biology, Qassim 51452, Saudi Arabia 3 Health INTI International Nilai 71800, Negeri Sembilan, Malaysia * Correspondence: [email protected] Received: 21 September 2024; Revised: 7 October Accepted: November Published: 17 January 2025 Abstract: The current study evaluated antibacterial activities methanol leaf extracts from aegyptica against clinical isolates Staphylococcus aureus, Salmonella typhi, Escherichia coli. analysis revealed presence various bioactive compounds, including alkaloids, flavonoids, tannins, while anthraquinones were absent. Both demonstrated significant activity, particularly Gram-negative bacteria (S. typhi), with minimum inhibitory concentrations (MIC) as low 12.5 mg/mL bactericidal (MBC) 25 for balsamina, MIC MBC 50 L. aegyptica. These findings suggest that these plants have potential sources agents, warranting further pharmaceutical investigation.

Language: Английский

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