Discovery and Characterization of an Atypical Crustin Antimicrobial Peptide from Pollicipes pollicipes DOI Creative Commons
Wei Zhang,

Lianghong Wei,

Pengyu Chen

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(12), P. 526 - 526

Published: Nov. 22, 2024

Crustins are a family of antimicrobial peptides (AMPs) that play pivotal role in the innate immune system crustaceans. The discovery novel AMPs from natural sources is crucial for expanding our current database these peptides. Here, we identified and characterized member crustin family, named

Language: Английский

Advancements in Antibacterial Therapy: Feature Papers DOI Creative Commons
Giancarlo Angeles Flores,

Gaia Cusumano,

Roberto Venanzoni

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 557 - 557

Published: March 1, 2025

Antimicrobial resistance (AMR) is a growing global health crisis that threatens the efficacy of antibiotics and modern medical interventions. The emergence multidrug-resistant (MDR) pathogens, exacerbated by misuse in healthcare agriculture, underscores urgent need for innovative solutions. (1) Background: AMR arises from complex interactions between human, animal, environmental health, further aggravated overuse inadequate regulation antibiotics. Conventional treatments are increasingly ineffective, necessitating alternative strategies. Emerging approaches, including bacteriophage therapy, antimicrobial peptides (AMPs), nanotechnology, microbial extracellular vesicles (EVs), CRISPR-based antimicrobials, provide novel mechanisms complement traditional combating resistant pathogens. (2) Methods: This review critically analyzes advanced antibacterial strategies conjunction with systemic reforms such as stewardship programs, One Health framework, surveillance tools. These methods can enhance detection, guide interventions, promote sustainable practices. Additionally, economic, logistical, regulatory challenges impeding their implementation evaluated. (3) Results: technologies, CRISPR exhibit promising potential targeting mechanisms. However, disparities resource distribution barriers hinder widespread adoption. Public–private partnerships agriculture practices critical to overcoming these obstacles. (4) Conclusions: A holistic integrated approach essential mitigating impact AMR. By aligning therapeutic policies, fostering interdisciplinary collaboration, ensuring equitable distribution, we develop response this 21st-century challenge.

Language: Английский

Citations

2

Potential Antimicrobial properties of cytosine β-D-riboside derivatives through molecular dynamics and molecular docking exploration with bacterial and fungal proteins DOI Creative Commons
Sarkar M. A. Kawsar,

Rahnuma Tabassum,

Nasrin Sultana Munia

et al.

Aspects of Molecular Medicine, Journal Year: 2025, Volume and Issue: unknown, P. 100077 - 100077

Published: March 1, 2025

Language: Английский

Citations

0

Sulfide-modified zero-valent iron enhanced activation of sodium bromate for sulfamethoxazole removal: sulfur species and multiple reactive species role DOI

Minyi Yu,

Y. C. Mao, Shang Gao

et al.

Journal of environmental chemical engineering, Journal Year: 2025, Volume and Issue: unknown, P. 116316 - 116316

Published: March 1, 2025

Language: Английский

Citations

0

Development and characterization of alginate and chitosan hybrid films for dual administration of neomycin and lidocaine DOI
Vitor Lopes Chagas, Lucas dos Santos Silva, Carlos Eduardo Morais de Sousa

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142632 - 142632

Published: March 1, 2025

Language: Английский

Citations

0

Assessment of the antimicrobial activity of Dinuclear Pt/Pt, Pt/Zn and Pt/cu complexes: Insights from docking studies DOI
Svetlana Jeremić, Violeta Jakovljević,

Darko Anđelković

et al.

Inorganica Chimica Acta, Journal Year: 2025, Volume and Issue: unknown, P. 122723 - 122723

Published: April 1, 2025

Language: Английский

Citations

0

Affinity of cefditoren for penicillin-binding proteins in bacteria and its relationship with antibiotic sensitivity DOI

Yixin Qi,

Qixue Shi,

Lingman Ma

et al.

Archives of Microbiology, Journal Year: 2024, Volume and Issue: 206(12)

Published: Nov. 18, 2024

Language: Английский

Citations

1

Patterns of antibiotic resistance genes and virulence factor genes in the gut microbiome of patients with osteoarthritis and rheumatoid arthritis DOI Creative Commons
Yaqi Guo,

Hang Feng,

Lin Du

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Nov. 20, 2024

The gut microbiome compositions of osteoarthritis (OA) and rheumatoid arthritis (RA) patients have been revealed; however, the functional genomics, particularly antibiotic resistance genes (ARGs) virulence factor (VFGs), not yet explored.

Language: Английский

Citations

0

Discovery and Characterization of an Atypical Crustin Antimicrobial Peptide from Pollicipes pollicipes DOI Creative Commons
Wei Zhang,

Lianghong Wei,

Pengyu Chen

et al.

Marine Drugs, Journal Year: 2024, Volume and Issue: 22(12), P. 526 - 526

Published: Nov. 22, 2024

Crustins are a family of antimicrobial peptides (AMPs) that play pivotal role in the innate immune system crustaceans. The discovery novel AMPs from natural sources is crucial for expanding our current database these peptides. Here, we identified and characterized member crustin family, named

Language: Английский

Citations

0