Advancements in Antibacterial Therapy: Feature Papers
Microorganisms,
Journal Year:
2025,
Volume and Issue:
13(3), P. 557 - 557
Published: March 1, 2025
Antimicrobial
resistance
(AMR)
is
a
growing
global
health
crisis
that
threatens
the
efficacy
of
antibiotics
and
modern
medical
interventions.
The
emergence
multidrug-resistant
(MDR)
pathogens,
exacerbated
by
misuse
in
healthcare
agriculture,
underscores
urgent
need
for
innovative
solutions.
(1)
Background:
AMR
arises
from
complex
interactions
between
human,
animal,
environmental
health,
further
aggravated
overuse
inadequate
regulation
antibiotics.
Conventional
treatments
are
increasingly
ineffective,
necessitating
alternative
strategies.
Emerging
approaches,
including
bacteriophage
therapy,
antimicrobial
peptides
(AMPs),
nanotechnology,
microbial
extracellular
vesicles
(EVs),
CRISPR-based
antimicrobials,
provide
novel
mechanisms
complement
traditional
combating
resistant
pathogens.
(2)
Methods:
This
review
critically
analyzes
advanced
antibacterial
strategies
conjunction
with
systemic
reforms
such
as
stewardship
programs,
One
Health
framework,
surveillance
tools.
These
methods
can
enhance
detection,
guide
interventions,
promote
sustainable
practices.
Additionally,
economic,
logistical,
regulatory
challenges
impeding
their
implementation
evaluated.
(3)
Results:
technologies,
CRISPR
exhibit
promising
potential
targeting
mechanisms.
However,
disparities
resource
distribution
barriers
hinder
widespread
adoption.
Public–private
partnerships
agriculture
practices
critical
to
overcoming
these
obstacles.
(4)
Conclusions:
A
holistic
integrated
approach
essential
mitigating
impact
AMR.
By
aligning
therapeutic
policies,
fostering
interdisciplinary
collaboration,
ensuring
equitable
distribution,
we
develop
response
this
21st-century
challenge.
Language: Английский
Potential Antimicrobial properties of cytosine β-D-riboside derivatives through molecular dynamics and molecular docking exploration with bacterial and fungal proteins
Aspects of Molecular Medicine,
Journal Year:
2025,
Volume and Issue:
unknown, P. 100077 - 100077
Published: March 1, 2025
Language: Английский
Sulfide-modified zero-valent iron enhanced activation of sodium bromate for sulfamethoxazole removal: sulfur species and multiple reactive species role
Minyi Yu,
No information about this author
Y. C. Mao,
No information about this author
Shang Gao
No information about this author
et al.
Journal of environmental chemical engineering,
Journal Year:
2025,
Volume and Issue:
unknown, P. 116316 - 116316
Published: March 1, 2025
Language: Английский
Development and characterization of alginate and chitosan hybrid films for dual administration of neomycin and lidocaine
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
unknown, P. 142632 - 142632
Published: March 1, 2025
Language: Английский
Assessment of the antimicrobial activity of Dinuclear Pt/Pt, Pt/Zn and Pt/cu complexes: Insights from docking studies
Inorganica Chimica Acta,
Journal Year:
2025,
Volume and Issue:
unknown, P. 122723 - 122723
Published: April 1, 2025
Language: Английский
Affinity of cefditoren for penicillin-binding proteins in bacteria and its relationship with antibiotic sensitivity
Yixin Qi,
No information about this author
Qixue Shi,
No information about this author
Lingman Ma
No information about this author
et al.
Archives of Microbiology,
Journal Year:
2024,
Volume and Issue:
206(12)
Published: Nov. 18, 2024
Language: Английский
Patterns of antibiotic resistance genes and virulence factor genes in the gut microbiome of patients with osteoarthritis and rheumatoid arthritis
Yaqi Guo,
No information about this author
Hang Feng,
No information about this author
Lin Du
No information about this author
et al.
Frontiers in Microbiology,
Journal Year:
2024,
Volume and Issue:
15
Published: Nov. 20, 2024
The
gut
microbiome
compositions
of
osteoarthritis
(OA)
and
rheumatoid
arthritis
(RA)
patients
have
been
revealed;
however,
the
functional
genomics,
particularly
antibiotic
resistance
genes
(ARGs)
virulence
factor
(VFGs),
not
yet
explored.
Language: Английский
Discovery and Characterization of an Atypical Crustin Antimicrobial Peptide from Pollicipes pollicipes
Wei Zhang,
No information about this author
Lianghong Wei,
No information about this author
Pengyu Chen
No information about this author
et al.
Marine Drugs,
Journal Year:
2024,
Volume and Issue:
22(12), P. 526 - 526
Published: Nov. 22, 2024
Crustins
are
a
family
of
antimicrobial
peptides
(AMPs)
that
play
pivotal
role
in
the
innate
immune
system
crustaceans.
The
discovery
novel
AMPs
from
natural
sources
is
crucial
for
expanding
our
current
database
these
peptides.
Here,
we
identified
and
characterized
member
crustin
family,
named
Language: Английский