Behavioral Cooperation or Conflict of Human Intestinal Roundworms and Microbiomes: A Bio-Activity Perspective DOI Creative Commons
Meisam Khazaei, Malihe Parsasefat, Aisa Bahar

et al.

Cells, Journal Year: 2025, Volume and Issue: 14(7), P. 556 - 556

Published: April 7, 2025

Human infections are greatly impacted by intestinal nematodes. These nematodes, which encompass the large roundworms, have a direct impact on human health and well-being due to their close cohabitation with host’s microorganisms. When nematodes infect host, microbiome composition changes, this can ability control parasites. We aimed find out if small roundworms produce substances that antimicrobial properties respond microbial environment, immune regulatory reactions altered in humans lacking gut microbes. There is no doubt different living intestines alter balance of bacteria. Nonetheless, our knowledge about parasite’s influence remains restricted. The last two decades study revealed type iron utilized activation unique virulence factors. However, some roundworm proteins like P43, makes up portion worm’s excretory-secretory product, an unknown role. This review explores how bacterial network contributes adaptability opportunistic pathogen, allowing it successfully host environments.

Language: Английский

Behavioral Cooperation or Conflict of Human Intestinal Roundworms and Microbiomes: A Bio-Activity Perspective DOI Creative Commons
Meisam Khazaei, Malihe Parsasefat, Aisa Bahar

et al.

Cells, Journal Year: 2025, Volume and Issue: 14(7), P. 556 - 556

Published: April 7, 2025

Human infections are greatly impacted by intestinal nematodes. These nematodes, which encompass the large roundworms, have a direct impact on human health and well-being due to their close cohabitation with host’s microorganisms. When nematodes infect host, microbiome composition changes, this can ability control parasites. We aimed find out if small roundworms produce substances that antimicrobial properties respond microbial environment, immune regulatory reactions altered in humans lacking gut microbes. There is no doubt different living intestines alter balance of bacteria. Nonetheless, our knowledge about parasite’s influence remains restricted. The last two decades study revealed type iron utilized activation unique virulence factors. However, some roundworm proteins like P43, makes up portion worm’s excretory-secretory product, an unknown role. This review explores how bacterial network contributes adaptability opportunistic pathogen, allowing it successfully host environments.

Language: Английский

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