Photothermal Bacterial Clearance Using Gold Nanoshells Grown on Chitosan Nanoparticles Dielectric Templates DOI Creative Commons

Patricia Dolores Martinez-Flores,

Marisol Gastelum-Cabrera, Manuel G. Ballesteros‐Monrreal

et al.

Drugs and Drug Candidates, Journal Year: 2025, Volume and Issue: 4(2), P. 18 - 18

Published: April 22, 2025

Background/Objectives: Bacterial infections remain among the top ten major public health concerns, contributing to a high number of incidences disease and mortality worldwide, exacerbated by rise multidrug-resistant bacteria (MDRB). Consequently, it is crucial develop novel antimicrobial strategies, including use functional nanoparticles. Gold nanoparticles (GNPs) have emerged as promising candidates due their unique optical properties, particularly ability efficiently convert absorbed light into heat through photothermal (PT) effect, which can be harnessed for eradication. Methods: Chitosan was modified with 3-mercaptopropionic acid introduce sulfur groups, facilitating gold deposition onto chitosan nanoparticle (TCNPs) surface. The shell subsequently formed via seed-mediated method, wherein seeds were adsorbed TCNPs further grown form shell. Photothermal effect on bacterial viability evaluated. Results: size 178 nm spherical morphology obtained. After (TCNP@Au) exhibited conversion efficiency 31%, making them agent clearance. Notably, Escherichia coli significantly reduced in presence TCNP@Au almost eradicated upon PT treatment. In contrast, TCNP@Aus non-toxic Staphylococcus aureus. Conclusions: demonstrated favorable presenting nanoplatform antibacterial applications, against Gram-negative bacteria. However, investigation required optimize PT-based strategies Gram-positive bacteria, such S.

Language: Английский

Influences of wall shear stress on bacterial colony formation at pipe joints and elbows in drinking water distribution systems DOI

Lingjiang Lu,

Lei Fu, Zhaowei Liu

et al.

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 72, P. 107595 - 107595

Published: April 1, 2025

Language: Английский

Citations

0
Photothermal Bacterial Clearance Using Gold Nanoshells Grown on Chitosan Nanoparticles Dielectric Templates DOI Creative Commons

Patricia Dolores Martinez-Flores,

Marisol Gastelum-Cabrera, Manuel G. Ballesteros‐Monrreal

et al.

Drugs and Drug Candidates, Journal Year: 2025, Volume and Issue: 4(2), P. 18 - 18

Published: April 22, 2025

Background/Objectives: Bacterial infections remain among the top ten major public health concerns, contributing to a high number of incidences disease and mortality worldwide, exacerbated by rise multidrug-resistant bacteria (MDRB). Consequently, it is crucial develop novel antimicrobial strategies, including use functional nanoparticles. Gold nanoparticles (GNPs) have emerged as promising candidates due their unique optical properties, particularly ability efficiently convert absorbed light into heat through photothermal (PT) effect, which can be harnessed for eradication. Methods: Chitosan was modified with 3-mercaptopropionic acid introduce sulfur groups, facilitating gold deposition onto chitosan nanoparticle (TCNPs) surface. The shell subsequently formed via seed-mediated method, wherein seeds were adsorbed TCNPs further grown form shell. Photothermal effect on bacterial viability evaluated. Results: size 178 nm spherical morphology obtained. After (TCNP@Au) exhibited conversion efficiency 31%, making them agent clearance. Notably, Escherichia coli significantly reduced in presence TCNP@Au almost eradicated upon PT treatment. In contrast, TCNP@Aus non-toxic Staphylococcus aureus. Conclusions: demonstrated favorable presenting nanoplatform antibacterial applications, against Gram-negative bacteria. However, investigation required optimize PT-based strategies Gram-positive bacteria, such S.

Language: Английский

Citations

0