Royal Society of Chemistry eBooks,
Journal Year:
2024,
Volume and Issue:
unknown, P. 70 - 107
Published: Dec. 20, 2024
This
chapter
delves
into
the
pivotal
role
that
biosensors
play
in
transforming
healthcare
practices.
Biosensors,
comprising
bioreceptors,
transducers,
and
signal
processors,
detect
measure
biological
substances,
offering
high
sensitivity
specificity
various
applications.
With
applications
ranging
from
disease
detection
to
personalized
medicine,
they
have
revolutionized
diagnostic
practices,
enabling
early
tailored
treatment
regimens.
explores
significance
of
sectors,
highlighting
their
unparalleled
accuracy
rapid
capabilities.
Despite
potential,
face
challenges
related
cost-effectiveness,
underscoring
need
for
critical
evaluation
comparison
approaches.
Through
a
comprehensive
analysis
biosensor
detection,
metabolic
diseases,
monitoring,
breath-based
diagnostics,
DNA/RNA
retinal
prosthesis,
phenotypic
cancer
medical
mycology,
MRI
contrast
imaging,
this
aims
provide
insights
efficacy,
feasibility,
potential
impact
on
delivery.
By
contributing
ongoing
discussions
field,
will
inspire
further
research
innovation,
advancing
use
as
transformative
tools
improving
delivery
patient
outcomes.
Medical Gas Research,
Journal Year:
2025,
Volume and Issue:
15(2), P. 318 - 326
Published: Jan. 18, 2025
Recent
advancements
in
artificial
intelligence–enabled
medical
gas
sensing
have
led
to
enhanced
accuracy,
safety,
and
efficiency
healthcare.
Medical
gases,
including
oxygen,
nitrous
oxide,
carbon
dioxide,
are
essential
for
various
treatments
but
pose
health
risks
if
improperly
managed.
This
review
highlights
the
integration
of
intelligence
sensing,
enhancing
traditional
sensors
through
advanced
data
processing,
pattern
recognition,
real-time
monitoring
capabilities.
Artificial
improves
ability
detect
harmful
levels,
enabling
immediate
intervention
prevent
adverse
effects.
Moreover,
developments
nanotechnology
resulted
materials,
such
as
metal
oxides
carbon-based
nanomaterials,
which
increase
sensitivity
selectivity.
These
innovations,
combined
with
intelligence,
support
continuous
patient
predictive
diagnostics,
paving
way
future
breakthroughs
care.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 24, 2025
Abstract
Breath
analysis
offers
a
non‐invasive
approach
to
modern
diagnostics
by
capturing
volatile
organic
compounds
(VOCs)
in
exhaled
breath.
However,
current
breath
technologies
face
challenges
like
humidity
sensitivity,
high
costs,
and
biodegradable
solutions,
limiting
their
scalability
environmental
sustainability.
This
study
presents
paper‐based,
biodegradable,
humidity‐insensitive
electronic
nose
(e‐nose)
sensor
array
integrated
into
mask
for
real‐time
analysis.
The
sensors,
coated
with
hydrophobic
polymer
coating,
ensure
robust
insensitivity
humidity,
enabling
reliable
detection
of
VOCs
even
high‐moisture
environments.
mask‐integrated
e‐nose
facilitates
monitoring
applications
such
as
alcohol
consumption
tracking
respiratory
health
assessment.
For
the
latter,
Tuberculosis
(TB)
is
selected
representative
use
case,
achieving
89%
accuracy
disease
diagnosis
recovery
using
pre‐trained
deep‐learning
model.
fully‐biodegradable
paper‐based
naturally
degrades
soil
within
months,
underscoring
its
eco‐friendly
design
suitability
disposable
monitoring.
work
introduces
sustainable,
user‐friendly
potential
personalized
healthcare
Foods,
Journal Year:
2024,
Volume and Issue:
13(14), P. 2268 - 2268
Published: July 18, 2024
Chromatographic
analysis
of
phenolic
phytochemicals
in
foods
has
significantly
advanced
over
the
past
decade
(2014-2024),
meeting
increasing
demands
for
precision
and
efficiency.
This
review
covers
both
conventional
chromatographic
techniques
used
detecting
foods.
Conventional
methods
like
High-Performance
Liquid
Chromatography,
Ultra
Thin-Layer
Gas
Chromatography
are
discussed,
along
with
their
benefits
limitations.
Advanced
techniques,
including
Hydrophilic
Interaction
Nano-LC,
Multidimensional
Capillary
Electrophoresis,
highlighted
innovations
improved
capabilities.
The
addresses
challenges
current
methods,
emphasizing
need
standardized
validated
procedures
according
to
Food
Drug
Administration,
European
Cooperation
Accreditation
Laboratories,
International
Organization
Standardization
guidelines
ensure
reliable
reproducible
results.
It
also
considers
novel
strategies
reducing
environmental
impact
advocating
sustainable
practices
analytical
chemistry.
Advanced Theory and Simulations,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 12, 2025
Abstract
Human
breath
contains
over
3000
volatile
organic
compounds,
abnormal
concentrations
of
which
can
indicate
the
presence
certain
diseases.
Recently,
metal–organic
framework
(MOF)‐metal
oxide
composite
materials
have
been
explored
for
chemiresistive
sensor
applications,
however
their
ability
to
detect
compounds
associated
with
specific
diseases
remains
unknown.
In
this
work,
a
new
high‐throughput
computational
protocol
evaluating
sensing
MOF‐metal
toward
small
is
presented.
This
uses
cluster‐based
method
accelerated
structure
relaxation,
and
combination
binding
energies
density‐of‐states
analysis
evaluate
ability,
latter
measured
using
Wasserstein
distances.
applied
case
material
NM125‐TiO
2
shown
be
consistent
previously
reported
experimental
results
system.
The
100
human‐breath
spanning
13
different
examined.
Statistical
inference
then
used
identify
subsequent
efforts
should
focus
on.
Overall,
work
provides
tools
research,
while
also
illustrating
how
science
integrated
into
field
preventative
medicine.
Cells,
Journal Year:
2025,
Volume and Issue:
14(6), P. 402 - 402
Published: March 10, 2025
Metabolic
reprogramming
is
a
hallmark
of
cancer,
with
cancer
cells
acquiring
many
unique
metabolic
traits
to
support
malignant
growth,
and
extensive
intra-
inter-tumour
heterogeneity.
Understanding
these
characteristics
presents
opportunities
in
precision
medicine
for
both
diagnosis
therapy.
However,
despite
its
potential,
phenotyping
has
lagged
behind
genetic,
transcriptomic,
immunohistochemical
profiling
clinical
applications.
This
partly
due
the
lack
single
experimental
technique
capable
entire
metabolome,
necessitating
use
multiple
technologies
approaches
capture
full
range
plasticity.
review
examines
repertoire
tools
available
metabolism,
demonstrating
their
applications
preclinical
settings.
It
also
case
studies
illustrating
how
metabolomic
been
integrated
other
omics
gain
insights
into
tumour
biology
guide
treatment
strategies.
information
aims
assist
researchers
selecting
most
effective
highlights
importance
combining
different
techniques
comprehensively
understand
metabolism.
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(6), P. 2025 - 2025
Published: March 17, 2025
Background/Objectives:
Emerging
laboratory
technologies,
such
as
breathomics,
may
enhance
the
early
diagnosis
of
psychiatric
disorders,
including
Bipolar
Disorder
(BD).
This
study
investigates
detection
volatile
sulfur
compounds
(VSCs)
in
exhaled
breath
potential
biomarkers
for
BD,
comparing
VSC
levels
between
individuals
with
healthy
controls,
and
non-pathological
hyperactivity.
Methods:
A
matched
case–control
was
conducted
involving
24
patients
BD
95
controls
recruited
at
University
Hospital
Cagliari.
Controls
were
selected
using
a
matched-pair
design
based
on
age
(±5
years)
sex
through
block-matching
technique
to
ensure
comparability
cases.
Participants
underwent
interviews,
completed
Mood
Questionnaire
(MDQ),
had
their
breaths
analyzed
VSCs
gas
chromatograph
(OralChroma™).
randomized
sex.
Results:
Patients
exhibited
significantly
higher
methyl
mercaptan
(CH3SH)
compared
(18.62
±
5.04
vs.
9.45
18.64
ppb,
p
=
0.022).
Among
without
those
positive
MDQ
scores
showed
lower
CH3SH
than
negative
(9.17
5.42
15.05
18.03);
however,
this
difference
did
not
reach
statistical
significance
(p
0.254),
highlighting
how
deep
connection
some
clinical
aspects
needs
be
investigated
more
thoroughly.
Conclusions:
The
results
suggest
correlation
oral
dysbiosis
metabolic
alterations
being
cases
controls.
Further
studies
are
needed
validate
use
investigate
role
