Clinical applications of neurofeedback based on sensorimotor rhythm: a systematic review and meta-analysis DOI Creative Commons

Tatiana Ferri Ribeiro,

Marcelo Alves Carriello, Eugenio Pereira de Paula

et al.

Frontiers in Neuroscience, Journal Year: 2023, Volume and Issue: 17

Published: Nov. 20, 2023

Background Among the brain-machine interfaces, neurofeedback is a non-invasive technique that uses sensorimotor rhythm (SMR) as clinical intervention protocol. This study aimed to investigate applications of SMR understand its effectiveness in different pathologies or symptoms. Methods A systematic review with meta-analysis EEG-based performed using pre-selected publication databases. qualitative analysis these studies was Consensus tool on Reporting and Experimental Design Neurofeedback (CRED-nf). The Meta-analysis efficacy carried out Review Manager software, version 5.4.1 (RevMan 5; Cochrane Collaboration, Oxford, UK). Results includes 44 studies, which only 27 had some kind control condition, five were double-blinded, three reported blind follow-up throughout intervention. included total sample 203 individuals between stroke fibromyalgia. Studies multiple sclerosis, insomnia, quadriplegia, paraplegia, mild cognitive impairment excluded due absence group results based post-intervention scales. Statistical indicated patients did not benefit from interventions when compared other therapies (Std. mean. dif. 0.31, 95% CI 0.03–0.60, p = 0.03), there no significant heterogeneity among classified moderate I 2 46% -value 0.06. Patients diagnosed fibromyalgia showed, by means quantitative analysis, better for used −0.73, −1.22 −0.24, 0.001). Thus, performing pooled conditions, differences observed standard therapy (0.05, 95%, −0.20 −0.30, 0.69), presence substantial 92.2%, < 0.001. Conclusion We conclude although electrophysiological patterns contemplates interest numerous researchers existence research presents promising results, it currently possible point benefits form Therefore, necessary develop more robust greater rigorous methodology can provide population.

Language: Английский

Cognitive Training with Neurofeedback Using NIRS Improved Cognitive Functions in Young Adults: Evidence from a Randomized Controlled Trial DOI Creative Commons
Rui Nouchi,

Haruka Nouchi,

Jérôme Dinet

et al.

Brain Sciences, Journal Year: 2021, Volume and Issue: 12(1), P. 5 - 5

Published: Dec. 21, 2021

(1) Background: A previous study has shown that cognitive training with neurofeedback (CT-NF) using down-regulation improves functions in young adults. Neurofeedback two strategies for manipulating brain activity (down-regulation and upregulation). However, the benefit of CT-NF upregulation is still unknown. In this study, we investigated whether a wide range compared to alone. (2) Methods: double-blinded randomized control trial (RCT), 60 adults were randomly assigned one three groups: group, CT alone an active (ACT) group who played puzzle game. Participants groups used same device (tablet PC 2ch NIRS (near-infrared spectroscopy)) performed game 20 min every day four weeks. We measured during all groups, but only CT-NFs received NF. also before after intervention period. (3) Results: The showed superior beneficial effects on episodic memory, working attention ACT groups. addition, increase CT, which was associated improvements function. (4) Discussion: This first demonstrated strategy Our results suggest greater activities would enhance from CT.

Language: Английский

Citations

20
Effectiveness of Electroencephalography Neurofeedback for Improving Working Memory and Episodic Memory in the Elderly: A Meta-Analysis DOI Creative Commons
Yu‐Ru Lin, Tien‐Wei Hsu,

Che-Wei Hsu

et al.

Medicina, Journal Year: 2024, Volume and Issue: 60(3), P. 369 - 369

Published: Feb. 22, 2024

Background and Objective: Existing evidence indicates the potential benefits of electroencephalography neurofeedback (NFB) training for cognitive function. This study aims to comprehensively review all available investigating effectiveness NFB on working memory (WM) episodic (EM) in elderly population. Material Methods: A systematic search was conducted across five databases identify clinical trials examining impact function healthy individuals or those with mild impairment (MCI). The co-primary outcomes focused changes WM EM. Data synthesis performed using a random-effects meta-analysis. Results: Fourteen (n = 284) were included analysis. findings revealed that associated improved (k 11, reported as Hedges’ g 0.665, 95% confidence [CI] 0.473 0.858, p < 0.001) EM 12, 0.595, 0.333 0.856, elderly, moderate effect sizes. Subgroup analyses demonstrated had positive both EM, not only population (WM: k 7, 0.495, 0.213 0.778, 0.001; EM: 6, 0.729, 0.483 0.976, but also MCI 0.812, 0.549 1.074, 0.503, 0.088 0.919, 0.018). Additionally, sufficient time (totaling more than 300 min) significant improvement 0.743, 0.510 0.516, 0.156 0.876, 0.005); however, such observed groups inadequate time. Conclusions: results suggest is enhancement individuals, particularly when adequate (exceeding provided. These underscore dementia prevention rehabilitation.

Language: Английский

Citations

2
Accelerating P300-based neurofeedback training for attention enhancement using iterative learning control: a randomised controlled trial DOI Creative Commons
Sandra-Carina Noble, Eva Woods, Tomás E. Ward

et al.

Journal of Neural Engineering, Journal Year: 2024, Volume and Issue: 21(2), P. 026006 - 026006

Published: Feb. 23, 2024

. Neurofeedback (NFB) training through brain-computer interfacing has demonstrated efficacy in treating neurological deficits and diseases, enhancing cognitive abilities healthy individuals. It was previously shown that event-related potential (ERP)-based NFB using a P300 speller can improve attention adults by incrementally increasing the difficulty of spelling task. This study aims to assess impact task adaptation on ERP-based adults. To achieve this, we introduce novel employing iterative learning control (ILC) compare it against an existing method group with random variation.

Language: Английский

Citations

2
Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study DOI Creative Commons
Stefanie Enriquez‐Geppert,

Jaroslav Krc,

Fiachra O'Higgins

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 379(1915)

Published: Oct. 21, 2024

Executive function deficits, common in psychiatric disorders, hinder daily activities and may be linked to diminished neural plasticity, affecting treatment training responsiveness. In this pioneering study, we evaluated the feasibility preliminary efficacy of psilocybin-assisted frontal-midline theta neurofeedback (NF), a neuromodulation technique leveraging neuroplasticity, improve executive functions (EFs). Thirty-seven eligible participants were randomized into an experimental group (

Language: Английский

Citations

2
Cognitive training based on functional near-infrared spectroscopy neurofeedback for the elderly with mild cognitive impairment: a preliminary study DOI Creative Commons
Ilju Lee, Dohyun Kim, Sehwan Kim

et al.

Frontiers in Aging Neuroscience, Journal Year: 2023, Volume and Issue: 15

Published: July 26, 2023

Mild cognitive impairment (MCI) is often described as an intermediate stage of the normal decline associated with aging and dementia. There a growing interest in various non-pharmacological interventions for MCI to delay onset inhibit progressive deterioration daily life functions. Previous studies suggest that training (CT) contributes restoration working memory brain-computer-interface technique can be applied elicit more effective treatment response. However, these techniques have certain limitations. Thus, this preliminary study, we neurofeedback paradigm during CT increase function patients MCI.Near-infrared spectroscopy (NIRS) was used provide by measuring changes oxygenated hemoglobin prefrontal cortex. Thirteen elderly who received CT-neurofeedback sessions four times on left dorsolateral cortex (dlPFC) once week were recruited participants.Compared pre-intervention, activity targeted brain region increased when participants first engaged training; after 4 weeks training, oxygen saturation significantly decreased dlPFC. The demonstrated improved compared pre-intervention correlated performance.Our results applications evaluating brain-computer interfaces aid elucidation subjective mental workload may create additional or task workloads due CT.

Language: Английский

Citations

6
Adaptive P300-Based Brain-Computer Interface for Attention Training: Protocol for a Randomized Controlled Trial DOI Creative Commons
Sandra-Carina Noble, Eva Woods, Tomás E. Ward

et al.

JMIR Research Protocols, Journal Year: 2023, Volume and Issue: 12, P. e46135 - e46135

Published: May 23, 2023

The number of people with cognitive deficits and diseases, such as stroke, dementia, or attention-deficit/hyperactivity disorder, is rising due to an aging, in the case a growing population. Neurofeedback training using brain-computer interfaces emerging means easy-to-use noninvasive rehabilitation. A novel application neurofeedback P300-based interface has previously shown potential improve attention healthy adults.This study aims accelerate iterative learning control optimize task difficulty adaptive P300 speller task. Furthermore, we hope replicate results previous for training, benchmark comparison. In addition, effectiveness personalizing during will be compared nonpersonalized adaptation.In this single-blind, parallel, 3-arm randomized controlled trial, 45 adults recruited randomly assigned experimental group 1 2 groups. This involves single session, where participants receive through During task's progressively increased, which makes it more difficult maintain their performance. encourages focus. Task either adapted based on participants' performance (in 1) chosen 2). Changes brain patterns before after analyzed different approaches. Participants complete random dot motion so that any transfer effects other tasks can evaluated. Questionnaires used estimate fatigue compare perceived workload between groups.This been approved by Maynooth University Ethics Committee (BSRESC-2022-2474456) registered ClinicalTrials.gov (NCT05576649). Participant recruitment data collection began October 2022, expect publish 2023.This task, making attractive option individuals its ease use speed. successful replication from study, would provide further evidence support tool.ClinicalTrials.gov NCT05576649; https://clinicaltrials.gov/ct2/show/NCT05576649.DERR1-10.2196/46135.

Language: Английский

Citations

5
Neurofeedback training can modulate task-relevant memory replay rate in rats DOI Creative Commons
Anna K. Gillespie,

Daniela Astudillo Maya,

Eric L. Denovellis

et al.

eLife, Journal Year: 2023, Volume and Issue: 12

Published: Sept. 12, 2023

Hippocampal replay – the time-compressed, sequential reactivation of ensembles neurons related to past experience is a key neural mechanism memory consolidation. Replay typically coincides with characteristic pattern local field potential activity, sharp-wave ripple (SWR). Reduced SWR rates are associated cognitive impairment in multiple models neurodegenerative disease, suggesting that clinically viable intervention promote SWRs and would prove beneficial. We therefore developed neurofeedback paradigm for rat subjects which detection triggered rapid positive feedback context memory-dependent task. This training protocol increased prevalence task-relevant during targeted period by changing temporal dynamics occurrence. increase was also behavioral forms compensation after period. These findings reveal short-timescale regulation generation demonstrate an effective strategy modulating hippocampal replay.

Language: Английский

Citations

5
From Lab to Life: Challenges and Perspectives of fNIRS for Hemodynamic Neurofeedback in Real-World Environments DOI Open Access
Franziska Klein, Simon H. Kohl, Michael Lührs

et al.

Published: Nov. 17, 2023

Neurofeedback allows individuals to monitor and self-regulate their brain activity, potentially improving human function. Beyond the traditional electrophysiological approach using primarily electroencephalography, haemodynamics measured with functional magnetic resonance imaging (fMRI) more recently, near-infrared spectroscopy (fNIRS) have been used (haemodynamic-based neurofeedback), particularly improve spatial specificity of neurofeedback. Over recent years, especially fNIRS has attracted great attention because it offers several advantages over fMRI such as increased user accessibility, cost-effectiveness mobility—the latter being most distinct feature fNIRS. The next logical step would be transfer haemodynamic-based neurofeedback protocols that already proven validated by mobile However, this undertaking is not always easy, since novices may miss important fNIRS-specific methodological challenges. This review aimed at researchers from different fields who seek exploit unique capabilities for It carefully addresses challenges suggestions possible solutions. If raised are addressed further developed, could emerge a useful technique its own application potential—the targeted training activity in real-world environments, thereby significantly expanding scope scalability applications.

Language: Английский

Citations

5
Turning markers into targets – scoping neural circuits for motor neurofeedback training in Parkinson’s disease DOI Creative Commons
David Marc Anton Mehler

Brain-Apparatus Communication A Journal of Bacomics, Journal Year: 2022, Volume and Issue: 1(1), P. 1 - 27

Published: April 6, 2022

Purpose Motor symptoms of patients suffering from Parkinson's disease (PD) are currently mainly treated with dopaminergic pharmacology, and where indicated, deep brain stimulation. In the last decades, a substantial body literature has described neurophysiological correlates related to both motor treatment effects. These mechanistic insights allow, at least theoretically, for precise targeting neural processes responsible PD symptoms.Materials methods Literature search was conducted identify electrophysiological hemodynamic signals that may serve as targets future neurofeedback training protocols.Results particular alpha, beta gamma oscillations over cortex show high potential training. Hemodynamic functional magnetic resonance imaging (fMRI) higher spatial resolution provides additional about network activity between cortical subcortical regions in response established treatments. fMRI based (NFT) further allows involved networks. near infrared spectroscopy (fNIRS) be suitable transfer technology more cost-efficient NFT.Conclusions This scoping review presents summarises markers promising NFT interventions informed by validated circuit models. Recommendations best practice study design reporting provided, highlighting importance adequate control conditions statistical power.

Language: Английский

Citations

8
Neurofeedback training can modulate task-relevant memory replay rate in rats DOI Open Access
Anna K. Gillespie, Daniela A. Astudillo Maya, Eric L. Denovellis

et al.

Published: March 27, 2024

Hippocampal replay – the time-compressed, sequential reactivation of ensembles neurons related to past experience is a key neural mechanism memory consolidation. Replay typically coincides with characteristic pattern local field potential activity, sharp-wave ripple (SWR). Reduced SWR rates are associated cognitive impairment in multiple models neurodegenerative disease, suggesting that clinically viable intervention promote SWRs and would prove beneficial. We therefore developed neurofeedback paradigm for rat subjects which detection triggered rapid positive feedback context memory-dependent task. This training protocol increased prevalence task-relevant during targeted period by changing temporal dynamics occurrence. increase was also behavioral forms compensation after period. These findings reveal short-timescale regulation generation demonstrate an effective strategy modulating hippocampal replay.

Language: Английский

Citations

1