Authorea (Authorea),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Nov. 17, 2023
Most
scientist
agree
that
subjective
tinnitus
is
the
pathological
result
of
an
interaction
damage
to
peripheral
auditory
system
and
central
neuroplastic
adaptations.
Here
we
investigate
such
related
adaptations
in
primary
cortex
(AC)
13
days
after
noise
trauma
induction
by
quantifying
density
extracellular
matrix
(ECM)
AC
Mongolian
gerbils
(Meriones
unguiculatus).
The
ECM
has
been
shown
be
relevant
for
processes
synaptic
stability
within
cortex.
We
utilized
a
mild
monaural
acoustic
9
induce
sham
exposure
3
control
animals.
Tinnitus
was
assessed
behavioral
response
paradigm.
Four
animals
did
show
(T),
remaining
5
(NT)
(C)
not
percept.
quantified
using
immunofluorescence
luminance
Wisteria
floribunda
lectin-fluoresceine-5-isothiocyanate
(WFA-FITC)
on
histological
slices
AC,
relative
non-auditory
brainstem
as
reference
area.
found
WFA-FITC
NT
significantly
different
from
C
However,
significant
increase
T
animals’
ACs
compared
or
cortices.
This
effect
exclusively
side
contralateral
ear.
These
results
point
process
stabilization
connections
which
may
involved
chronic
manifestation
tinnitus.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 14, 2024
Abstract
Most
scientist
agree
that
subjective
tinnitus
is
the
pathological
result
of
an
interaction
damage
to
peripheral
auditory
system
and
central
neuroplastic
adaptations.
Here
we
investigate
such
related
adaptations
in
primary
cortex
(AC)
7
13
days
after
noise
trauma
induction
by
quantifying
density
extracellular
matrix
(ECM)
AC
Mongolian
gerbils
(Meriones
unguiculatus).
The
ECM
has
been
shown
be
relevant
for
processes
synaptic
stability
within
cortex.
We
utilized
a
mild
monaural
acoustic
overall
22
induce
sham
exposure
16
control
(C)
animals.
Tinnitus
was
assessed
behavioral
response
paradigm.
Animals
were
separated
presence
(T)
or
absence
(NT)
percept
task.
quantified
using
immunofluorescence
luminance
Wisteria
floribunda
lectin-fluoresceine-5-isothiocyanate
(WFA-FITC)
on
histological
slices
AC,
relative
non-auditory
brainstem
as
reference
area.
At
both
timepoints,
found
WFA-FITC
NT
animals
not
significantly
different
from
C
However,
significant
increase
T
animals’
ACs
compared
cortices.
This
effect
exclusively
side
contralateral
ear.
These
results
point
hemisphere
specific
process
stabilization
connections
which
may
involved
chronic
manifestation
tinnitus.
Biology,
Journal Year:
2024,
Volume and Issue:
13(8), P. 631 - 631
Published: Aug. 18, 2024
Noise
is
commonly
seen
as
a
disturbance
but
can
influence
any
system
it
interacts
with.
This
may
not
always
be
desirable,
sometimes
improve
the
system’s
performance.
For
example,
stochastic
resonance
phenomenon
where
adding
right
amount
of
noise
to
weak
signal
makes
easier
detect.
known
sub-threshold
detection.
detection’s
natural
fingerprint
fact
that
threshold
values
follow
an
inverse
U-shaped
curve
intensity
increases.
The
minimum
value
point
maximum
sensitivity
and
represents
optimal
divides
dynamics
in
two.
Below
point,
we
find
beneficial
branch,
facilitate
better
Above
common
detrimental
concept
found:
hinders
nervous
controls
movements
bodily
functions
human
body.
By
reducing
sensory
thresholds,
balance
these
functions.
Additionally,
researchers
have
wondered
if
could
applied
different
senses
or
motor
mechanisms
enhance
our
abilities.
In
this
work,
used
reaction
times.
We
tested
hypothesis
visual
times
decrease
significantly
when
subject’s
perception
branch
closer
than
outside
condition.
Auditory
was
introduced
101
subjects
using
interface
capable
searching
for
place
subject
close
point.
When
comparing
results,
decreased
were
at
compared
such
conditions.
These
results
reveal
possibility
approach
performance
tasks
requiring
faster
times,
sports.
Authorea (Authorea),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Nov. 17, 2023
Most
scientist
agree
that
subjective
tinnitus
is
the
pathological
result
of
an
interaction
damage
to
peripheral
auditory
system
and
central
neuroplastic
adaptations.
Here
we
investigate
such
related
adaptations
in
primary
cortex
(AC)
13
days
after
noise
trauma
induction
by
quantifying
density
extracellular
matrix
(ECM)
AC
Mongolian
gerbils
(Meriones
unguiculatus).
The
ECM
has
been
shown
be
relevant
for
processes
synaptic
stability
within
cortex.
We
utilized
a
mild
monaural
acoustic
9
induce
sham
exposure
3
control
animals.
Tinnitus
was
assessed
behavioral
response
paradigm.
Four
animals
did
show
(T),
remaining
5
(NT)
(C)
not
percept.
quantified
using
immunofluorescence
luminance
Wisteria
floribunda
lectin-fluoresceine-5-isothiocyanate
(WFA-FITC)
on
histological
slices
AC,
relative
non-auditory
brainstem
as
reference
area.
found
WFA-FITC
NT
significantly
different
from
C
However,
significant
increase
T
animals’
ACs
compared
or
cortices.
This
effect
exclusively
side
contralateral
ear.
These
results
point
process
stabilization
connections
which
may
involved
chronic
manifestation
tinnitus.
