
BMC Anesthesiology, Journal Year: 2024, Volume and Issue: 24(1)
Published: Dec. 19, 2024
Language: Английский
BMC Anesthesiology, Journal Year: 2024, Volume and Issue: 24(1)
Published: Dec. 19, 2024
Language: Английский
Nursing in Critical Care, Journal Year: 2025, Volume and Issue: 30(2)
Published: Feb. 17, 2025
Abstract Background Post‐operative delirium is a complication with long‐lasting consequences for both patients and their families. This particularly true those transferred to the intensive care unit after surgery, where incidence of post‐operative high, patient outcomes are often poor. Despite acknowledged role family engagement in management, previous research has mainly focused on patients, limited exploration shared experiences between members. Aim study aims explore members during episodes better understand unmet needs. Study Design A qualitative descriptive was conducted at tertiary general hospital. Eighteen pairs two other were interviewed. Data collected through face‐to‐face semi‐structured interviews within first week patients' discharge from analysed using thematic analysis. Results Four major themes emerged: (1) dyadic relationship must be understood context emotional behavioural experiences; (2) family's history may predispose delirium; (3) prevent development (4) inadequate communication health providers or families negatively affect outcomes. Conclusions presents significant physical challenges Addressing these requires improved families, as well strategies that emphasize early support collaboration care. Relevance Clinical Practice Patients should considered earlier essential. Health systems adapt practices meet dynamic needs promoting more comprehensive critical
Language: Английский
Citations
1Springer eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 151 - 168
Published: Jan. 1, 2025
Citations
0Psikhiatriya, Journal Year: 2025, Volume and Issue: 23(1), P. 28 - 38
Published: May 8, 2025
Background: the increasing number of cardiac surgeries in older patients with serious cardiovascular diseases, frequent development postoperative delirium, its unfavorable prognosis, and underdiagnosis certain types delirium determined relevance this study. The aim was to identify clinical who underwent surgery. Patients Methods: a total 157 participated prospective observational study undergoing conducted at surgery cardiology intensive care departments Sverdlovsk Regional Clinical Hospital No.1. Clinical, psychopathological, psychometric, statistical methods were used. Results: 31 (19.7% operated study) identified early period. Based on psychometric (total scores Confusion Assessment Method Intensive Care Unit Richmond Agitation-Sedation Scale) psychopathological assessment patients’ condition, heterogeneity revealed. Different including hypoactive type 87.1% f, mixed 9.7% hyperactive 3.2% cases. syndromic structure is different. Discussion: different allow us assume pathogenetic mechanisms. This may partially explain insufficient sensitivity diagnostic tools Conclusion : improvement typology necessary predict develop for prevention.
Language: Английский
Citations
0Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12
Published: May 15, 2025
Objective To evaluate the efficacy of transcranial direct current stimulation (tDCS) in reducing incidence postoperative delirium (POD) elderly patients undergoing hip fracture surgery. Methods and analysis This single-center, double-blind, randomized controlled trial will enroll 160 participants aged 65 years older, scheduled for elective surgery under spinal anesthesia. Participants be randomly assigned to either active-tDCS group or sham-tDCS group. The receive two sessions: one pre-surgery post-surgery, with electrodes positioned over left dorsolateral prefrontal cortex right supraorbital area. Each session includes 15-second ramp-up phase at start, 20 min simulation 2 mA ramp-down end. sham procedures no actual delivered. Functional brain activity monitored before after each procedure assess changes cortical activation connectivity using functional near-infrared spectroscopy (fNIRS). primary outcome measure POD, assessed 3-Min Diagnostic Interview Confusion Assessment Method (3D-CAM). Secondary outcomes include severity delirium, pain, anxiety, depression, cognitive function, sleep quality. Trial registration was registered ClinicalTrials.gov (NCT06678529) on Oct 22, 2024.
Language: Английский
Citations
0Aging Clinical and Experimental Research, Journal Year: 2024, Volume and Issue: 36(1)
Published: Feb. 17, 2024
Abstract Background Postoperative delirium (POD) is a common complication with poor prognosis in the elderly, but its mechanism has not been fully elucidated. There evidence that changes synaptic activity brain are closely related to occurrence of POD. And neuronal pentraxin 2 (NPTX2) can regulate vivo. Aims This study aims explore whether decreased NPTX2 levels affects POD and cerebrospinal fluid (CSF) biomarkers mediate this association. Methods In prospective cohort study, we interviewed patients knee/hip replacement 1 day before surgery collect patient information assess their cognitive function. CSF was extracted for measuring other on surgery. postoperative follow-up visits were performed 1–7 days after Results Finally, 560 included study. The divided into group NPOD (non-POD) group. had median age 80 years, female proportion 45%, BMI 24.1 kg/m , years education 9 years. Mann–Whitney U test showed significantly lower group, compared ( P < 0.05). Univariate binary logistic regression analysis reduced protected against (crude OR = 0.994, 95% CI 0.993–0.995, 0.001). receiver-operating characteristic (ROC) curve indicated level high predictive value Mediation analyses T-tau (mediating 21%) P-tau 29%) significant mediating effects association between Conclusion associated Low may be an independent protective factor could occurrence. Clinical trial registration number (TRN): ChiCTR2200064740, Date Registration: 2022-10-15.
Language: Английский
Citations
1BMC Surgery, Journal Year: 2024, Volume and Issue: 24(1)
Published: Oct. 1, 2024
Language: Английский
Citations
1Cureus, Journal Year: 2023, Volume and Issue: unknown
Published: Aug. 26, 2023
Aims The aim of the present study was to investigate preoperative Trail Making Test (TMT) and its association with postoperative delirium. Materials methods This cross-sectional, observational consisted 51 patients admitted surgical ward for any planned operative procedure. Consenting provided their sociodemographic information, Hospital Anxiety Depression Scale (HADS), Montreal Cognitive Assessment (MoCA) test, were applied. Results A total (66.7% male 33.3% female) categorized as "normal" group (n=34), completing TMT in time, "slow" (n=17). mean age 45.05 ± 13.69 normal 44.29 10.95 slow group. HADS score 15.02 9.52 11.64 5.73, respectively, these two groups (t = -1.577; degrees freedom {df} 47.11; p 0.121). However, scored significantly higher MoCA scores comparison (26.35 1.06 24.29 1.10, respectively) -6.410; df 49; 0.000). Conclusions shows that can indicate effectively cognitive decline patients, which predicts
Language: Английский
Citations
1BMC Anesthesiology, Journal Year: 2024, Volume and Issue: 24(1)
Published: Dec. 19, 2024
Language: Английский
Citations
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