Advances in medical diagnosis, treatment, and care (AMDTC) book series, Journal Year: 2024, Volume and Issue: unknown, P. 195 - 218

Published: Dec. 13, 2024

Inflammation of the central nervous system (CNS), which various infectious diseases can induce and significantly affect cognitive functions. The review enriches current understanding neuroinflammation pathology suggests novel diagnostic/therapeutic strategies for impairments. Pathogens cause disruption blood-brain barrier (BBB), could be due to a repertoire mechanism viz. interplay inflammatory cytokines reactive oxygen species. influence on function is immense multifactorial. Neuroinflammatory responses in acute phase result impairments, like memory deficits, attention span being reduced, executive dysfunction. However, cases persistent lead long-term decline neurodegenerative processes. mechanisms underlying these changes are diverse, including disruptions synaptic plasticity, alterations neurotransmitter systems, neuronal cell death.

Language: Английский