Absence of Modulatory Effects of Cerebellar Transcranial Alternating Current Stimulation in the Theta Band on Fear Learning in Men DOI

Sarah Johanna Schellen,

Philip Zeidan,

Thomas Ernst

et al.

Published: Jan. 1, 2023

Fear is a vital defense mechanism to potential threats, which influenced by the cerebellum. While cerebellum’s role in acquiring fear responses well understood, limited knowledge exists about its involvement extinction. In this study, we investigated effects of cerebellar theta band transcranial alternating current stimulation (ctACS) administered during extinction training, based on previous evidence from animal studies suggesting oscillations associative memory formation. To end, thirty-seven healthy right-handed male participants were recruited for two-day differential renewal paradigm. On day 1, they underwent acquisition training context A followed B. 2, recall was tested contexts and One group received ctACS (6 Hz) training. The other sham ctACS. Although both groups demonstrated ability previously learned distinguish between low high threat stimuli, no significant differences observed groups, indicating that at frequency range did not impact acquired study. Nevertheless, using could still be useful future research, including brain imaging studies, better understand how cerebellum involved processes.

Language: Английский

The amygdala and fear memory DOI
Raphael Lamprecht

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0

Absence of Modulatory Effects of Cerebellar Transcranial Alternating Current Stimulation in the Theta Band on Fear Learning in Men DOI

Sarah Johanna Schellen,

Philip Zeidan,

Thomas Ernst

et al.

Published: Jan. 1, 2023

Fear is a vital defense mechanism to potential threats, which influenced by the cerebellum. While cerebellum’s role in acquiring fear responses well understood, limited knowledge exists about its involvement extinction. In this study, we investigated effects of cerebellar theta band transcranial alternating current stimulation (ctACS) administered during extinction training, based on previous evidence from animal studies suggesting oscillations associative memory formation. To end, thirty-seven healthy right-handed male participants were recruited for two-day differential renewal paradigm. On day 1, they underwent acquisition training context A followed B. 2, recall was tested contexts and One group received ctACS (6 Hz) training. The other sham ctACS. Although both groups demonstrated ability previously learned distinguish between low high threat stimuli, no significant differences observed groups, indicating that at frequency range did not impact acquired study. Nevertheless, using could still be useful future research, including brain imaging studies, better understand how cerebellum involved processes.

Language: Английский

Citations

0