Harnessing Intelligence from Brain Cells In Vitro DOI Creative Commons
Brett J. Kagan, Forough Habibollahi, Bradley Watmuff

et al.

The Neuroscientist, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Harnessing intelligence from brain cells in vitro requires a multidisciplinary approach integrating wetware, hardware, and software. Wetware comprises the themselves, where differentiation induced pluripotent stem offers ethical scalability; hardware typically involves life support system setup to record activity deliver stimulation cells; software is required control process signals coming going cells. This review provides broad summary of foundational technologies underpinning these components, along with outlining importance technology integration. Of particular that this new ability extend beyond traditional methods assess primarily survival spontaneous neural cultures. Instead, focus returns core function tissue: neurocomputational information respond accordingly. Therefore, also covers work that, despite relatively early state current technology, has provided novel meaningful understandings field neuroscience opening exciting avenues for future research.

Language: Английский

Harnessing Intelligence from Brain Cells In Vitro DOI Creative Commons
Brett J. Kagan, Forough Habibollahi, Bradley Watmuff

et al.

The Neuroscientist, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Harnessing intelligence from brain cells in vitro requires a multidisciplinary approach integrating wetware, hardware, and software. Wetware comprises the themselves, where differentiation induced pluripotent stem offers ethical scalability; hardware typically involves life support system setup to record activity deliver stimulation cells; software is required control process signals coming going cells. This review provides broad summary of foundational technologies underpinning these components, along with outlining importance technology integration. Of particular that this new ability extend beyond traditional methods assess primarily survival spontaneous neural cultures. Instead, focus returns core function tissue: neurocomputational information respond accordingly. Therefore, also covers work that, despite relatively early state current technology, has provided novel meaningful understandings field neuroscience opening exciting avenues for future research.

Language: Английский

Citations

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