Exercise as a Therapeutic Intervention in Multiple Sclerosis DOI Creative Commons
Lara A. Pilutti, Sarah J. Donkers

Multiple Sclerosis Journal, Journal Year: 2024, Volume and Issue: 30(5_suppl), P. 30 - 35

Published: Dec. 1, 2024

The role of exercise as a therapeutic intervention in multiple sclerosis (MS) has shifted over time. Early views surrounding MS advocated for caution against participation. With increasing evidence, perspectives to promote approach symptom management. Recent efforts have focused on understanding the potential disease-modifying effects MS, although this work is still its infancy. While continue optimize prescriptions and unravel underlying mechanisms effects, current knowledge implementation gaps limit accessibility therapy all people living with MS. This topical review based an invited presentation '

Language: Английский

Exercise-based telerehabilitation for patients with multiple sclerosis using physical activity: a systematic review DOI Creative Commons
Michaela Sládečková, Jan Kočica, Eva Vlčková

et al.

Journal of Rehabilitation Medicine, Journal Year: 2024, Volume and Issue: 56, P. jrm40641 - jrm40641

Published: Nov. 13, 2024

Background: Telerehabilitation is a practical option for individuals with multiple sclerosis (MS) to engage in sustained physical activity without -visiting rehabilitation facility. The aim of this systematic review was evaluate the feasibility, effectiveness, safety, and adherence exercise-based telerehabilitation as compared usual care MS patients. Methods: A comprehensive literature search adhering PRISMA guidelines conducted, focusing on studies published English since 2000. protocol registered PROSPERO. selection process involved strict criteria, including people MS, centred regular exercise, control group receiving care, valid exercise testing, randomized controlled trial principles. Methodological quality assessed using TESTEX tool, ensuring rigour study design reporting. Results: Among 281 records screened, 10 met criteria. interventions varied format outcomes were diverse tests questionnaires. Despite variations, collectively demonstrated promising feasibility minimal withdrawals minor adverse events. Effectiveness varied, 5 out showing significant improvements intervention group. Adherence rates ranged from 38% 100%. Conclusion: In most aspects, comparable centre-based rehabilitation.

Language: Английский

Citations

3
Uma revisão narrativa da literatura sobre o tratamento da esclerose múltipla DOI Creative Commons
Leonardo Pereira Levada,

Milena Beatriz Benício Neves,

Ana Beatriz Teles de Almeida

et al.

Brazilian Journal of Implantology and Health Sciences, Journal Year: 2024, Volume and Issue: 6(2), P. 1785 - 1796

Published: Feb. 20, 2024

O trabalho aborda a esclerose múltipla (EM) como uma doença complexa do sistema nervoso central, discutindo interação entre processos inflamatórios, desmielinização e degeneração neuroaxonal. Destaca-se importância das células imunes na penetração da barreira hematoencefálica formação de lesões desmielinizantes. Enquanto os tratamentos para forma recidivante EM são eficazes, as opções progressiva não limitadas. Com revisão meticulosa literatura, apresentadas diversas abordagens terapêuticas, incluindo substâncias naturais, modificação microbioma intestinal, terapia reabilitação novas terapias farmacológicas, inibidores BTK o ocrelizumabe. São destacados desafios gestão fadiga, tratamento em pacientes com doenças concomitantes idosos, além questões relacionadas à saúde reprodutiva. estudo ressalta necessidade abordagem multidisciplinar personalizada, reconhecendo complexidade contínua pesquisa melhorar resultados qualidade vida dos pacientes.

Citations

2
Inflammation and physical activity in multiple sclerosis patients. A systematic review and meta-analysis DOI Creative Commons
Valeria Bellisario, Giulia Squillacioti, Federica Ghelli

et al.

Complementary Therapies in Medicine, Journal Year: 2024, Volume and Issue: 82, P. 103040 - 103040

Published: April 10, 2024

Due to the inflammatory nature of multiple sclerosis (MS), most widely used therapeutic approach targets immune response but can comprise side effects (e.g. secondary immunosuppression). For these reasons, among non-pharmaceutical interventions without known effects, physical activity (PA) gained importance because it is feasible, safe and a supportive complementary treatment strategy alleviate symptoms in MS subjects. Consequently, main aim this systematic review analyze effect PA protocols, as therapy, on status patients.

Language: Английский

Citations

1
Muscle immune cells protect mitochondrial organelles during exercise DOI
Gérald Coulis, S. Armando Villalta

Nature, Journal Year: 2023, Volume and Issue: 625(7993), P. 35 - 36

Published: Dec. 18, 2023

Language: Английский

Citations

2
Exercise as a Therapeutic Intervention in Multiple Sclerosis DOI Creative Commons
Lara A. Pilutti, Sarah J. Donkers

Multiple Sclerosis Journal, Journal Year: 2024, Volume and Issue: 30(5_suppl), P. 30 - 35

Published: Dec. 1, 2024

The role of exercise as a therapeutic intervention in multiple sclerosis (MS) has shifted over time. Early views surrounding MS advocated for caution against participation. With increasing evidence, perspectives to promote approach symptom management. Recent efforts have focused on understanding the potential disease-modifying effects MS, although this work is still its infancy. While continue optimize prescriptions and unravel underlying mechanisms effects, current knowledge implementation gaps limit accessibility therapy all people living with MS. This topical review based an invited presentation '

Language: Английский

Citations

0