Attentional state-synchronous peripheral electrical stimulation during action observation induced distinct modulation of corticospinal plasticity after stroke DOI Creative Commons

Chang Hyeon Jeong,

Hyunmi Lim, Jiye Lee

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: March 28, 2024

Introduction Brain computer interface-based action observation (BCI-AO) is a promising technique in detecting the user's cortical state of visual attention and providing feedback to assist rehabilitation. Peripheral nerve electrical stimulation (PES) conventional method used enhance outcomes upper extremity function by increasing activation motor cortex. In this study, we examined effects different pairings peripheral during BCI-AO tasks their impact on corticospinal plasticity. Materials methods Our innovative interventions decoded attentive watching task completion. This process involved rewarding cues while simultaneously activating afferent pathways through PES. Fifteen stroke patients were included analysis. All underwent 15 min program under four experimental conditions: without PES, with continuous triggered reverse PES application. was applied at ulnar wrist an intensity equivalent 120% sensory threshold frequency 50 Hz. The experiment conducted randomly least 3 days apart. To assess excitability, compared pre post-task (post 0, post 20 min) parameters evoked potential F waves conditions muscle affected hand. Results findings indicated that excitability hemisphere higher when synchronously AO training, using BCI watching. contrast, there no effect continuously or manner. paradigm promoted plasticity for up after Importantly, more evident over 65 years age. Conclusion results showed task-driven highly brain task, asynchronous study provides insight into how optimized technologies dependent conjunction other rehabilitation training could treatment-induced neural

Language: Английский

Effects of Electrical Stimulation on Activation of Mirror Neuron Network in Healthy Adults during Motor Execution and Imitation: An fNIRS Study DOI Creative Commons
Yao Cui,

Fang Cong,

Fubiao Huang

et al.

Journal of Integrative Neuroscience, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 7, 2025

Background: Observation, execution, and imitation of target actions based on mirror neuron network (MNN) have become common physiotherapy strategies. Electrical stimulation (ES) is a intervention to improve muscle strength motor control in rehabilitation treatments. It possible enhance MNN’s activation by combining execution (ME) (MI) with ES simultaneously. This study aims reveal whether could impact cortical during ME MI. Methods: We recruited healthy individuals assigned them randomly the group (CG) or experiment (EG). Participants EG performed MI tasks ES, while participants CG same two sham ES. utilized functional near-infrared spectroscopy (fNIRS) detect brain MNN without randomized block design paradigm was designed. Descriptive analysis oxy-hemoglobin (HbO) deoxy-hemoglobin (HbR) were used show hemoglobin (Hb) concentration changes after different event onsets both EG, linear mixed-effects model (LMM) HbO data employed analyze effect MNN. Results: A total 102 adults 72 participants’ analysed final report. The averaged Hb showed that increased HbR decreased most regions groups. LMM results can significantly inferior frontal gyrus, middle precentral gyrus MI, supplementary area, parietal lobule, superior temporal gyri activation, but statistical significance. Although did not reach significance ME, still positive effects overall activations. Conclusions: In this study, we present potential novel approaches combines strategies low-frequency activation. Our revealed has increase areas, providing evidence for related rehabilitative interventions device development. Clinical Trial Registration: registered China Registration Center (identifier: ChiCTR2200064082, 26, September 2022, https://www.chictr.org.cn/showproj.html?proj=178285).

Language: Английский

Citations

1
Effects and mechanisms of synchronous virtual reality action observation and electrical stimulation on upper extremity motor function and activities of daily living in patients with stroke: a protocol for a randomized controlled trial DOI Creative Commons
Yao Cui, Cong Fang, Ming Zeng

et al.

Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16

Published: April 4, 2025

Background Existing rehabilitation techniques are not satisfactory in improving motor function after stroke, resulting heavy social burdens. With discovery of mirror neuron system (MNS), action observation (AO) has become a promising strategy to promote learning rehabilitation. Based on MNS theory and virtual reality (VR) technology, we designed an innovative rehabilitative approach: synchronous 360° VR video AO (VRAO) neuromuscular electrical stimulation (NMES). We hypothesized that VRAO+NMES could enhance activation, thus improve upper limb activities daily living stroke survivors. Methods To explore the efficacy mechanism VRAO+NMES, this single center, evaluator blinded, prospective, two arm parallel group randomized controlled trial with 1:1 allocation ratio. The experiment will receive while control landscape combined NMES. Fugl-Meyer Assessment for Upper Extremity is primary outcome study, Brunstrom Recovery Stages Extremity, Manual Muscle Test, Range Motion, Modified Barthel Index, Functional Independence Measure secondary outcomes. In addition, functional near-infrared spectroscopy (fNIRS) surface electromyography (sEMG) be used evaluate activation brain regions related muscles, respectively. Discussion Applying therapy (AOT) popular, another study direction AOT combine it peripheral stimulations simultaneously. Due its full immersive characteristic multi-sensory input, videos based motivation engagement level participants. fNIRS sEMG test results may act as good biomarkers predict outcomes, helping select suitable candidates new intervention. Conclusion provide evidence feasibility potential clinical rehabilitation, applicability generalize use hospital, community, home settings. Clinical registration https://www.chictr.org.cn/showproj.html?proj=178276 , Identifier [ChiCTR2200063552].

Language: Английский

Citations

0
Advances in Brain-Computer Interface Controlled Functional Electrical Stimulation for Upper Limb Recovery After Stroke DOI Creative Commons
Yidan Zhang,

Yuling Gao,

Ziqi Zhou

et al.

Brain Research Bulletin, Journal Year: 2025, Volume and Issue: 226, P. 111354 - 111354

Published: April 23, 2025

Stroke often results in varying degrees of functional impairment, significantly affecting patients' quality daily life. In recent years, brain-computer interface-controlled electrical stimulation has offered new therapeutic approaches for post-stroke rehabilitation. This paper reviews the application BCI-FES recovery upper limb function after stroke and explores its underlying mechanisms. By analyzing relevant studies, aim is to provide a theoretical basis rehabilitating post-stroke, promote BCI-FES, offer guidance future clinical practice.

Language: Английский

Citations

0
The neurosocial alchemy of entrepreneurial transformation: a deep dive into extended mirror neuron system and neuroplasticity DOI
Vaneet Kaur

Entrepreneurship and Regional Development, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 15

Published: March 7, 2025

Language: Английский

Citations

0
Attentional state-synchronous peripheral electrical stimulation during action observation induced distinct modulation of corticospinal plasticity after stroke DOI Creative Commons

Chang Hyeon Jeong,

Hyunmi Lim, Jiye Lee

et al.

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: March 28, 2024

Introduction Brain computer interface-based action observation (BCI-AO) is a promising technique in detecting the user's cortical state of visual attention and providing feedback to assist rehabilitation. Peripheral nerve electrical stimulation (PES) conventional method used enhance outcomes upper extremity function by increasing activation motor cortex. In this study, we examined effects different pairings peripheral during BCI-AO tasks their impact on corticospinal plasticity. Materials methods Our innovative interventions decoded attentive watching task completion. This process involved rewarding cues while simultaneously activating afferent pathways through PES. Fifteen stroke patients were included analysis. All underwent 15 min program under four experimental conditions: without PES, with continuous triggered reverse PES application. was applied at ulnar wrist an intensity equivalent 120% sensory threshold frequency 50 Hz. The experiment conducted randomly least 3 days apart. To assess excitability, compared pre post-task (post 0, post 20 min) parameters evoked potential F waves conditions muscle affected hand. Results findings indicated that excitability hemisphere higher when synchronously AO training, using BCI watching. contrast, there no effect continuously or manner. paradigm promoted plasticity for up after Importantly, more evident over 65 years age. Conclusion results showed task-driven highly brain task, asynchronous study provides insight into how optimized technologies dependent conjunction other rehabilitation training could treatment-induced neural

Language: Английский

Citations

2