Interrelatedness of Neurocognitive Domain Functioning Between Unprompted and Prompted Identification Testing With Psychophysical Olfactory Evaluation in a Post‐COVID‐19 Cohort

World Journal of Otorhinolaryngology - Head and Neck Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: March 9, 2025

Language: Английский

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Impacto del COVID-19 en el desempeño cognitivo de los pacientes recuperados al año de la infección: estudio de cohortes utilizando la herramienta MoCA-T

Neurología Argentina, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

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Cognitive Impairments in Two Samples of Individuals with ME/CFS and Long COVID: A Comparative Analysis

Journal of Clinical Psychology in Medical Settings, Journal Year: 2025, Volume and Issue: unknown

Published: March 22, 2025

Language: Английский

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Changes in cerebrovascular reactivity within functional networks in older adults with long-COVID

Frontiers in Neurology, Journal Year: 2025, Volume and Issue: 16

Published: March 26, 2025

Introduction Cognitive symptoms are reported in the vast majority of individuals with long-COVID and there is growing support to suggest neurovascular mechanisms may play a role. Older adults at increased risk for developing complications associated COVID-19, including heightened cognitive decline. Cerebrovascular Reactivity (CVR), marker health, has been linked age related decline role long-COVID, however, this not yet explored. Methods The present study examined group differences CVR 31 older compared cognitively unimpaired without symptoms. Follow up analyses were conducted examine how was both subjective neuropsychological (NP) test performance. A subject-specific approach, Distribution-Corrected Z-scores (DisCo-Z), used. Results Analyses revealed demonstrated significantly greater incidence extreme clusters within brain (>100 voxels) functional networks thought drive attention executive function. Extreme positive positively number negatively correlated NP Discussion These findings among first provide link between functioning changes relevant aging mechanistic studies long-COVID.

Language: Английский

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Amnesic performance: performing Kinau’s archival isolation on the far side of the moon

Text and Performance Quarterly, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: March 26, 2025

Performances of forgetting are ubiquitous; in response, this essay presents a theory amnesic performance to constellate the esthetics and performances slippage, memory loss, ruin aftermath COVID-19. To advance my project performance, I bring forward contested figure C. A. Kinau within global history lunar documentation, as staged 2023 adaptation Judith Schalansky's An Inventory Losses. This work brings attention historical crisis documentation archives nineteenth-century selenography highlight modern traumas associated with COVID-19-induced loss social isolation.

Language: Английский

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Updates on the neurological manifestations of SARS-CoV-2 infection

Current Opinion in Infectious Diseases, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Purpose of review Since its emergence in 2020, the COVID-19 pandemic has created a global surge survivors experiencing neurologic effects from SARS-CoV-2 infection. This aims to provide an updated synthesis acute and chronic neurological manifestations COVID-19, outline current therapeutic strategies for these conditions. Recent findings Epidemiological studies have shown that patients with symptoms during infection tend poorer hospital functional outcomes. While risk adverse including cognitive dysfunction, headache, autonomic fatigue are thought be greatest following original strain alpha variant, they remain prevalent after subsequent less virulent strains as well. Some recent work also found link between structural brain changes. However, ongoing trials show promising results pharmacologic nonpharmacologic treatments targeting postacute sequelae COVID-19. Summary Lingering still pose considerable individual, healthcare system, socioeconomic repercussions. Both preventive multimodal treatment approaches necessary address Further research is required assess lasting impacts on nervous particularly potential contribution development neurodegenerative diseases.

Language: Английский

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Unravelling the complex and unexpected physiopathology of the post COVID-19 condition: a narrative review

Discover Viruses., Journal Year: 2025, Volume and Issue: 2(1)

Published: May 7, 2025

Language: Английский

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Investigating the Role of Serotonin Levels in Cognitive Impairments Associated with Long COVID-19

Chonnam Medical Journal, Journal Year: 2024, Volume and Issue: 60(3), P. 141 - 141

Published: Jan. 1, 2024

This study aimed to investigate the activation of inflammation process, triggered as an immune response combat invasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a highly transmissible and pathogenic that emerged in late 2019 has caused pandemic disease, named 'coronavirus disease 2019' (COVID-19). Several mechanisms contribute reduction serotonin levels, such impaired absorption dietary tryptophan, hindered transport via platelets, increased activity enzyme responsible for breaking down serotonin. Individuals seeking treatment long COVID-19 had lower levels their blood than those who fully recovered from infection. Furthermore, patients with also reduced tryptophan levels. The potential benefits supplementation or use selective reuptake inhibitors (SSRIs) improve cognitive impairments depressive anxiety disorders long-term patients. findings support response's pivotal role modulating further highlight intricate connection between system neurotransmitter regulation.

Language: Английский

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SARS-CoV-2 spike S1 protein induces microglial NLRP3-dependent neuroinflammation and cognitive impairment in mice

Experimental Neurology, Journal Year: 2024, Volume and Issue: 383, P. 115020 - 115020

Published: Oct. 18, 2024

Language: Английский

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Stroop task and practice effects demonstrate cognitive dysfunction in long COVID and myalgic encephalomyelitis / chronic fatigue syndrome

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 5, 2024

Background: The Stroop task was used to investigate differences in cognitive function between Long COVID (LC), Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) and healthy control subjects. Methods: Subjects viewed four color words or neutral (XXXX) stimuli with the same (congruent) different ink (incongruent). Cognitive conflict inferred from response times for pairings of prestimuli subsequent stimuli. Overall effects were assessed by univariate analysis time courses determined binned times. Results: LC ME/CFS had significantly longer than controls indicating dysfunction. Initial ranked > ME HC, decreased according power functions. At end (900s), = HC. Response slower following an incongruent prestimulus. Time series effect, facilitation, interference, surprise index practice law parameters generally similar LC, HC suggesting comparable patterns recruitment resources. prestimulus data analyzed generated positive interference that distinct stimulus effects. Conclusion: have global slowing cannot be overcome impaired communications network nodes during problem solving. Analysis matched – adds a new dimension understanding conflict. Brief Summary: dysfunction demonstrated using which found limitations

Language: Английский

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