Advancing Neuropsychological Rehabilitation in Primary Progressive Aphasia Based on Principles of Cognitive Neuroscience: A Scoping Review and Systematic Analysis of the Data DOI Creative Commons
Evgenia Gkintoni, Emilia Michou

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(12), P. 1234 - 1234

Published: Dec. 8, 2024

Background/Objectives: This systematic review of neuropsychological rehabilitation strategies for primary progressive aphasia will consider recent developments in cognitive neuroscience, especially neuroimaging techniques such as EEG and fMRI, to outline how these tools might be integrated into clinical practice maximize treatment outcomes. Methods: A search peer-reviewed literature from the last decade was performed following PRISMA guidelines across multiple databases. total 63 studies were included, guided by predefined inclusion exclusion criteria, with a focus on language PPA, interventions neuroimaging, mechanisms neuroplasticity. Results: Integration contributes increase efficacy critical information about neural underlying deficits aphasias. Traditional strategies, technology-assisted interventions, non-invasive brain stimulation hold considerable promise improvement. Neuroimaging also found necessary subtype-specific differentiation toward tailoring therapeutic intervention. Evidence shows that directed sustained using neuroplasticity can have long-term effects managing symptoms PPA. Conclusions: The present underlines necessity including neuroscience within enhance outcomes In addition, modalities fMRI are great importance understanding neurobiology disturbances guiding tailored interventions. Long-term benefits approaches should evaluated, their applicability routine practice.

Language: Английский

Addressing Phonological Deficit in Primary Progressive Aphasia With Behavioral Intervention and Transcranial Direct Current Stimulation DOI
Katlyn Victoria Nickels, Pélagie M. Beeson, Aneta Kielar

et al.

Journal of Speech Language and Hearing Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 38

Published: April 14, 2025

Purpose: Despite recognition of the underlying phonological impairment observed in logopenic and nonfluent variants primary progressive aphasia (PPA), there is relatively little treatment research directed toward strengthening skills. In this study, we focused on remediating deficits PPA. Specifically, hypothesized that behavioral intervention intended to strengthen manipulation skills sound–letter correspondences—coupled with transcranial direct current stimulation (tDCS)—would improve language abilities, especially written modality. Method: Twelve individuals or PPA 24 neurotypical adults completed neuropsychological assessment documented spoken those Phonological were consistently impaired relation other processes. Following a double-blind, crossover design, six randomized receive active tDCS during first phase, after 2-month break, they received second phase paired sham tDCS. The second. Language evaluated before each 2 months intervention. Results: Both groups (tDCS-first sham-first) made significant improvement transcoding response intervention, but who showed stronger gains ability. This group also positive changes narratives, which contained more grammatical sentences increased meaningful content accurate spelling. Conclusions: These data provide compelling evidence supporting an approach targets found improved resulted better functional communication ability (text-level writing) relevant everyday life. Positive outcomes strongest when was combined from beginning, suggesting combination may potentiate extend beyond initial period. Supplemental Material: https://doi.org/10.23641/asha.28598195

Language: Английский

Citations

0
Advancing Neuropsychological Rehabilitation in Primary Progressive Aphasia Based on Principles of Cognitive Neuroscience: A Scoping Review and Systematic Analysis of the Data DOI Creative Commons
Evgenia Gkintoni, Emilia Michou

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(12), P. 1234 - 1234

Published: Dec. 8, 2024

Background/Objectives: This systematic review of neuropsychological rehabilitation strategies for primary progressive aphasia will consider recent developments in cognitive neuroscience, especially neuroimaging techniques such as EEG and fMRI, to outline how these tools might be integrated into clinical practice maximize treatment outcomes. Methods: A search peer-reviewed literature from the last decade was performed following PRISMA guidelines across multiple databases. total 63 studies were included, guided by predefined inclusion exclusion criteria, with a focus on language PPA, interventions neuroimaging, mechanisms neuroplasticity. Results: Integration contributes increase efficacy critical information about neural underlying deficits aphasias. Traditional strategies, technology-assisted interventions, non-invasive brain stimulation hold considerable promise improvement. Neuroimaging also found necessary subtype-specific differentiation toward tailoring therapeutic intervention. Evidence shows that directed sustained using neuroplasticity can have long-term effects managing symptoms PPA. Conclusions: The present underlines necessity including neuroscience within enhance outcomes In addition, modalities fMRI are great importance understanding neurobiology disturbances guiding tailored interventions. Long-term benefits approaches should evaluated, their applicability routine practice.

Language: Английский

Citations

1