Acute sonographic changes in common carotid artery after NESA neuromodulation intervention in healthy adults: a randomized controlled clinical trial

Frontiers in Neuroscience, Journal Year: 2025, Volume and Issue: 19

Published: April 28, 2025

Introduction The endothelium plays a key role in vascular health, and its dysfunction is major risk factor for cardiovascular diseases (CVD). Non-invasive neuromodulation techniques, such as NESA, aim to improve tone function by targeting the autonomic nervous system. However, evidence regarding their acute effects still limited. Methods A randomized controlled trial was conducted with 40 participants divided into NESA ( n = 20) placebo groups. Both groups underwent 20-min interventions. Sonographic assessments of left CCA, including lumen diameter (LD), intima-media thickness (IMT), peak systolic velocity (PSV), along blood pressure (BP) heart rate (HR), were performed before immediately after intervention. Results Significant increases LD cross-sectional area (CSA) observed group compared p < 0.001), alongside decrease IMT 0.05). HR showed significant reduction post-intervention both groups, more pronounced effect 0.001). No changes found BP or PSV. Discussion findings demonstrate that induces immediate parameters, increased CSA decreased IMT. These results highlight measurable healthy individuals following

Language: Английский

Advancing Field of Neurocardiology: Physiologic Mechanisms and Devices

Published: Jan. 1, 2024

Language: Английский