Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review

Clinics and Practice, Journal Year: 2025, Volume and Issue: 15(1), P. 16 - 16

Published: Jan. 13, 2025

Chronic non-cancer pain, defined by the Center for Disease Control and Prevention (CDC) as lasting beyond three months, significantly affects individuals’ quality of life is often linked to various medical conditions or injuries. Its management complex. Cannabis, containing key compounds Delta-9-tetrahydrocannabinol (THC) cannabidiol (CBD), has garnered interest its potential in pain management, though it remains controversial due psychoactive effects illegal status many countries. THC provides relief blocking nociceptive stimuli but may potentially induce dependency. CBD calming antipsychotic properties. The inhalation cannabis offers quick poses respiratory risks, while oral administrations are safer act more slowly. Short-term use can impair cognition motor skills, long-term lead dependency cognitive decline, especially if used from an early age. Adverse vary gender prior use, with addiction mainly influenced genetics. Despite these patients report benefits, such improved reduced opioid although evidence inconclusive. legal landscape varies globally, some positive public health outcomes like opioid-related issues areas where legalized. Cannabis shows promise managing chronic risks necessitate cautious use. Future research should prioritize clinical trials establish optimal dosing, efficacy, safety, aiding development informed guidelines safe management. This review examines focusing on drawbacks, mechanisms, delivery methods, impact life.

Language: Английский

Effect of toluene on memory: A focus on humans, experimental models and treatment approaches

Advances in neurotoxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Hippocampal Apoptosis: Molecular Mechanisms Triggered by Toxic Cannabinoid Exposure: A Narrative Review

NeuroToxicology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский