Association of anxiety status and anxiety duration with constipation in adult Americans: a cross-sectional study using data from the NHANES 2007–2010

BMC Gastroenterology, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 22, 2025

Constipated patients may exhibit anxious behaviors, but the relationship between two remains unclear. This population-based study aims to investigate relationships of anxiety status and duration with constipation among U.S. adults. Using data from National Health Nutrition Examination Survey (NHANES) database spanning 2007 2010, a cross-sectional included 8945 participants was performed assess constipation. Participants' characteristics were presented using mean or proportion. Adjusted odds ratios (ORs) 95% confidence intervals (CIs) calculated multivariable logistic regression models. The analysis accounted for potential confounding factors, including gender, age, race/ethnicity, education level, marital status, PIR, BMI, smoking drinking chronic diseases, dietary intake. Subgroup analyses conducted ensure stability results. Smoothed curve fitting applied both linear nonlinear associations risk. Threshold effects assessed two-piecewise Of participants, 922 reported constipation, prevalence 10.3%. After adjusting individuals exhibited an increased risk (OR: 1.49, CI: 1.28–1.73). Stratified indicated that association remained relatively stable across different stratification levels. threshold effect revealed adults aged 20–60, while inverted U-shaped observed in those 60 older, inflection point at 10 days. variables correlated positively on left side not right. showed significant Additionally, age-dependent observed, particularly older.

Language: Английский

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Application of Functional Neurology Therapy in a Lactose-Intolerant Patient

Life, Journal Year: 2024, Volume and Issue: 14(8), P. 978 - 978

Published: Aug. 4, 2024

This case report examines the impact of a single session functional neurology on 35-year-old female patient diagnosed with lactose intolerance. The presented severe gastrointestinal symptoms, including frequent diarrhea, bloating, and vomiting upon dairy consumption. intervention aimed to reset dysfunctional neurological programs believed contribute her condition. study utilized standardized intolerance breath test measure hydrogen methane levels at various intervals before after treatment. Post-treatment results showed symptomatic relief reporting normalized bowel movements absence previous symptoms. Despite these improvements, biochemical markers higher time points (150 175 min) post-treatment remained similar pre-treatment values, indicating persistent malabsorption highlighting variability measurements. suggests that can significantly alleviate symptoms However, preliminary nature underscores need for further research involving larger sample sizes long-term follow-up fully understand treatment's efficacy underlying mechanisms.

Language: Английский

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Fermented dairy products for healthy ageing

Ageing & Longevity, Journal Year: 2025, Volume and Issue: 2. 2025, P. 111 - 116

Published: Feb. 27, 2025

Ageing is a key risk factor for numerous diseases, placing considerable socio-economic strain on the healthcare system. Fermented dairy products (FDPs), produced through fermentation of milk by specific microorganisms, offer an accessible, cost-effective, and safe dietary approach to mitigating age-related health issues. This review examines role FDPs in promoting longevity, emphasizing potential benefits existing challenges. While studies indicate multiple positive effects FDPs, obstacles such as compositional variability, cultural differences, need extensive long-term clinical trials persist. Overcoming these research gaps will enhance our understanding functional foods healthy ageing facilitating their inclusion evidence-based interventions. | Keywords: fermented milk; fermentation; longevity; benefits;

Language: Английский

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Gastrointestinal Cognition: Pain Catastrophizing in Irritable Bowel Syndrome, a Cross‐Sectional Study in Mexico

Neurogastroenterology & Motility, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

ABSTRACT Introduction and Aims Pain catastrophizing is more common in individuals with irritable bowel syndrome (IBS) than healthy individuals. Despite this, its prevalence impact Latin American populations remain under‐researched. Objective To assess pain differences between IBS patients subjects. Materials Methods Cross‐sectional study which subjects (HC) were recruited from our tertiary care center. diagnosis was established based on the Rome IV criteria. All participants answered scale (PCS), hospital anxiety depression (HAD), severity scoring system (IBS‐SSS). Group comparisons employed Student's t ‐test or Mann–Whitney U test, Pearson's Spearman's for correlations logistic regression to predictors. Results A total of 920 (66.4% women) a median age 23 years (range: 18–60) met inclusion had higher clinically significant compared (22.5% vs. 11%, p < 0.0001). When classified by symptom intensity, 52.2% severe symptoms exhibited catastrophizing, 25.3% moderate 14.7% mild ( Anxiety (OR 2.5, 95% CI 1.9–3.4, 0.0001), 1.7, 1.3–2.3, 2.3, 1.6–3.3, 0.0001) significantly associated IBS. Conclusions In Mexican IBS, gastrointestinal psychological distress. Comprehensive management this population should involve addressing cognitive patterns conjunction conventional treatments.

Language: Английский

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The role of microbiome in gut-brain-axis dysbiosis causing depression: From mechanisms to treatment

International review of neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Peculiarities of children’s health status after acute respiratory viral infections: a look at the problem, ways to solve it

CHILD`S HEALTH, Journal Year: 2024, Volume and Issue: 19(6), P. 397 - 406

Published: Nov. 2, 2024

Background. The article reviews literature data on the peculiarities of changes in health status children after acute respiratory viral infections (ARVI) various etiologies and development post-viral asthenic syndrome accompanied by physical, cognitive, emotional, psychological symptoms that significantly impair quality life. purpose study is to summarize features, mechanisms ARVI, methods correct these disorders, particular prescribing herbal remedies. Materials methods. Bibliographic information-analytical research were used. A theoretical analysis scientific from search databases PubMed, Web Science, Scopus, Google Scholar, Bri­tish Medical Journal for last 10 years was carried out possibility using, efficacy, safety, properties oregano, thyme, rose, small-leaved linden, hibiscus sabdariffa, calendula officinalis, black currant. Results. According review, incidence 36.8 %, with cognitive-emotional (84 %), sleep disturbances (74 decreased appetite (64 headaches (52 %) dominating clinical picture. persistence manifestations hinders adequate restoration child’s adaptive capacity fight against hypoxia, acidosis, metabolic disorders due syndrome. This determines urgency finding appropriate correction etiopathogenetic (inhibition oxidative stress, reduction acidosis liver function), immunoregulatory (improvement immune system), symptomatic appetite) effects. currant made it possible verify using this combination restore their ARVI. Conclusions. Phytocombination can be recommended children’s influenza, COVID-19, adenovirus infection, provide antioxidant, anti-inflammatory, antiviral effects, a positive impact gastrointestinal tract, nervous systems.

Language: Английский

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Adult neurogenesis and the microbiota-gut-brain axis in farm animals: underestimated and understudied parameters for improving welfare in livestock farming

Frontiers in Neuroscience, Journal Year: 2024, Volume and Issue: 18

Published: Nov. 27, 2024

Welfare in commercial livestock farming is becoming increasingly important current agriculture research. Unfortunately, there a lack of understanding about the neuronal mechanisms that underlie well-being on an individual level. Neuroplasticity hippocampus, subventricular zone (SVZ), olfactory bulb (OB) and hypothalamus may be essential regulatory components context farm animal behaviour welfare altered by providing environmental enrichment (EE). The importance pre-and probiotics as form EE microbiota-gut-brain axis (MGBA) has come under spotlight last 20 years, particularly contexts research into stress resilience. However, it could also system for farming. This review aims to present brief overview effects physiology animals briefly discusses literature behavioural flexibility, well inter-individual stress-coping styles their relationship welfare. Most importantly, we will summarise different forms neural plasticity animals, focusing neurogenesis various relevant brain regions. Furthermore, provide outlook connecting these neuroplasticity, stress, EE, MGBA measures modern farming, concentrating pigs.

Language: Английский

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The Gut Microbiota Is Involved in the Regulation of Cognitive Flexibility in Adolescent BALB/c Mice Exposed to Chronic Physical Stress and a High-Fat Diet

Microorganisms, Journal Year: 2024, Volume and Issue: 12(12), P. 2542 - 2542

Published: Dec. 10, 2024

Dysfunction in the prefrontal cortex can lead to cognitive inflexibility due multifactorial causes as included cardiometabolic disorders, stress, inadequate diets, well an imbalance of gut-brain axis microbiota. However, these risk factors have not been evaluated jointly. The purpose this study was evaluate effect physical stress (MS: Male Stress and FS: Female Stress) high-fat diet (MD: Diet FD: Diet) supplementation on gut microbiota flexibility. performed 47 mice, 30 male (M) 17 female (F) BALBc, exposed chronic (S) (D). Cognitive flexibility using Attentional Set-Shifting Test (ASST) composition terms relative abundance (%) alpha-beta diversity. Results showed that S D reduced mice ( Chronic a modify predictive function

Language: Английский

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Gut-Brain Axis: Exploring the Link Between Digestive Health and Mental Health

Indus journal of bioscience research., Journal Year: 2024, Volume and Issue: 2(2), P. 1307 - 1313

Published: Dec. 28, 2024

Objective: This study aimed to explore the link between digestive health and mental well-being through gut-brain axis, with a focus on microbial composition, dietary patterns, psychological outcomes in local population. Methodology: A retrospective was conducted at Hayatabad Medical Complex, Peshawar, April 2022 March 2023. total of 323 participants were included, 162 patients having gastrointestinal disorders 161 controls. Data demographics, analyzed. Independent t-tests chi-square tests used for statistical analysis, significance level set p < 0.05. Results: Patients exhibited significantly higher anxiety (11.2 ± 4.5 vs. 6.8 3.9, 0.001) depression scores (10.4 4.1 5.7 3.5, compared Microbial dysbiosis more prevalent disorder group (63%) than controls (32%, 0.001). Traditional patterns associated (p = 0.032). Demographics showed no significant differences age 0.246) or sex 0.431). Conclusion: The findings confirm strong association gut well-being, emphasizing role patterns. highlights need gut-targeted therapies public initiatives address axis.

Language: Английский

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Molecular Mechanisms Linking Omega-3 Fatty Acids and the Gut–Brain Axis

Molecules, Journal Year: 2024, Volume and Issue: 30(1), P. 71 - 71

Published: Dec. 28, 2024

The gut–brain axis (GBA) is a complex communication network connecting the gastrointestinal tract (GIT) and central nervous system (CNS) through neuronal, endocrine, metabolic, immune pathways. Omega-3 (n-3) fatty acids, particularly eicosapentaenoic acid (EPA) docosahexaenoic (DHA), are crucial food components that may modulate function of this molecular mechanisms. Derived mainly from marine sources, these long-chain polyunsaturated acids integral to cell membrane structure, enhancing fluidity influencing neurotransmitter signal transduction. Additionally, n-3 inflammation by altering eicosanoid production, reducing proinflammatory cytokines, promoting anti-inflammatory mediators. These actions help preserve integrity cellular barriers like intestinal blood–brain barriers. In CNS, EPA DHA support neurogenesis, synaptic plasticity, neurotransmission, improving cognitive functions. They also regulate hypothalamic–pituitary–adrenal (HPA) excessive cortisol associated with stress responses mental health disorders. Furthermore, influence composition gut microbiota, beneficial bacterial populations abundance contribute improve systemic immunity. Their multifaceted roles within GBA underscore their significance in maintaining homeostasis supporting well-being.

Language: Английский

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