Deciphering regeneration through non-model animals: A century of experiments on cephalopod mollusks and an outlook at the future DOI Creative Commons

Fabio De Sio,

Pamela Imperadore

Frontiers in Cell and Developmental Biology, Journal Year: 2023, Volume and Issue: 10

Published: Jan. 9, 2023

The advent of marine stations in the last quarter 19th Century has given biologists possibility observing and experimenting upon myriad organisms. Among them, cephalopod mollusks have attracted great attention from onset, thanks to their remarkable adaptability captivity a number biologically unique features including sophisticate behavioral repertoire, body patterning capacities under direct neural control complexity nervous system rivalling vertebrates. Surprisingly, capacity regenerate tissues complex structures, such as appendages, albeit been known for centuries, understudied over decades. Here, we will first review limited number, but fundamental studies on subject published between 1920 1970 discuss what they added our knowledge regeneration biological phenomenon. We also speculate how these relate epistemic disciplinary context, setting base study taxon. then frame peripherality cephalopods relation with experimental accessibility, comparison, established models, either simpler (such planarians), or more promising terms translation (urodeles). Last, explore potential growing relevance prospective models today, light novel opportunities provided by technological methodological advances, reconsider old problems new ones. recent development cutting-edge technologies made available cephalopods, like genome editing, is allowing important findings opening way toward avenues. contribution offered increase regenerative mechanisms through cross-species comparison lead better understanding cellular molecular machinery involved, shedding common pathways strategies different taxa evolved promote organs. Through dialogue biological/experimental historical/contextual perspectives, this article stimulate discussion around changing relations availability animal specificity, technical developments scientific trends contemporary biology medicine.

Language: Английский

Measuring Consciousness DOI
Mike Dacey

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 173 - 196

Published: Jan. 26, 2025

Abstract This chapter addresses the challenge of measuring consciousness. Consciousness does not seem to fit into standard scientific picture world. As such, it has been largely ignored across and scientifically minded fields. begun change in recent years. Using consciousness cephalopods as its example, this “distribution question,” question which animals are conscious first place. We need measures that can identify animals. However, candidate theories all still extremely uncertain contentious. The suggests a way thinking about their relation theory help further development these even we develop attempt learn conscious.

Language: Английский

Citations

1
Evolution of neuroglia DOI
Alexei Verkhratsky, Amaia M. Arranz, Katarzyna Ciuba

et al.

Annals of the New York Academy of Sciences, Journal Year: 2022, Volume and Issue: 1518(1), P. 120 - 130

Published: Oct. 26, 2022

Abstract The evolution of the nervous system progressed through cellular diversification and specialization functions. Conceptually, is composed electrically excitable neuronal networks connected by chemical synapses nonexcitable glial cells that provide for homeostasis defense. neuroglia began with emergence centralized proceeded a continuous increase in their complexity. In primate brain, especially brain humans, astrocyte lineage exceedingly complex, new types astroglial possibly involved interlayer communication integration.

Language: Английский

Citations

20
The Sentient Cell DOI
Arthur S. Reber, František Baluška, William B. Miller

et al.

Oxford University Press eBooks, Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 5, 2023

Abstract This volume is the natural follow-up to Arthur Reber’s 2019 book, The First Minds: Caterpillars, ‘Karyotes, and Consciousness (TFM). In that earlier work, Cellular Basis of (CBC) theory was developed based on a number efforts published in variety journals between 1997 as well talks, colloquia, presentations at conferences. core proposition TFM life mind are co-terminous. All organisms, all species extant extinct, sentient. have an existentially secure consciousness—without which they would been evolutionary dead-ends, unable survive chaotic, dangerous environment first appeared. And, importantly, forms sentience, cognitive functioning right up including those expressed by humans, evolved from original expression consciousness birth prokaryotes. unicellular widely accepted, foundational principle biological social sciences. CBC simply applies same sentience.

Language: Английский

Citations

13
Past, present, and future trends in octopus research DOI
Rui Rosa, Catarina Pereira Santos, Francisco O. Borges

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 421 - 454

Published: Jan. 1, 2024

Language: Английский

Citations

4
Why it hurts: with freedom comes the biological need for pain DOI
Keith D. Farnsworth, Robert W. Elwood

Animal Cognition, Journal Year: 2023, Volume and Issue: 26(4), P. 1259 - 1275

Published: April 8, 2023

Language: Английский

Citations

10
A chromosome-level reference genome for the common octopus, Octopus vulgaris (Cuvier, 1797) DOI Creative Commons
Dalila Destanović, Darrin T. Schultz, Ruth Styfhals

et al.

G3 Genes Genomes Genetics, Journal Year: 2023, Volume and Issue: 13(12)

Published: Oct. 18, 2023

Abstract Cephalopods are emerging animal models and include iconic species for studying the link between genomic innovations physiological behavioral complexities. Coleoid cephalopods possess largest nervous system among invertebrates, both cell counts brain-to-body ratio. Octopus vulgaris has been at center of a long-standing tradition research into diverse aspects cephalopod biology, including neural plasticity, learning memory recall, regeneration, sophisticated cognition. However, no chromosome-scale genome assembly was available O. to aid in functional studies. To fill this gap, we sequenced assembled common octopus, vulgaris. The final spans 2.8 billion basepairs, 99.34% which 30 scaffolds. Hi-C heatmaps support karyotype 1n = chromosomes. Comparisons with other octopus species' genomes show conserved pattern local rearrangements species. This new will further facilitate all various forms plasticity machinery underlying cognition, as well an understanding evolution.

Language: Английский

Citations

10
Introduction DOI
Mike Dacey

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: Jan. 26, 2025

Abstract The Introduction describes the science of animal minds with which book will engage, as well general orientation book. It introduces and seven challenges that make up separate chapters: 1 Underdetermination; 2 Anthropomorphic bias; 3 Modeling; 4 Integration Homology; 5 Ecological Validity; 6 Sample Size Generalizability; 7 Measuring Consciousness. For each these challenges, specific ways reframing problem are suggested be more fruitful. Finally, it positions among recent methodological work in philosophy minds, especially reaction to four features ‘standard practice’ comparative (animal) psychology.

Language: Английский

Citations

0
Conclusion: Of a Different Mind DOI
Mike Dacey

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 197 - 210

Published: Jan. 26, 2025

Abstract This Conclusion sums up the big-picture view of science animal minds which has emerged through book and reiterates actionable suggestions from earlier chapters. The general approach suggested is a holistic inference to best explanation, considers all relevant evidence may often require judgment calls about what counts as an instance capacity under question. replaces features current standard practice that have been difficult dislodge despite recent criticism. There are also specific model evaluation, statistical methods, experimental design, building.

Language: Английский

Citations

0
Underdetermination DOI
Mike Dacey

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 15 - 45

Published: Jan. 26, 2025

Abstract This chapter addresses the challenge of underdetermination theory by data: typically, many candidate theories or models animal minds are at least consistent with any given experimental result. has reached its purest form as “the logical problem” in debate about chimpanzee mind-reading. The suggests a shift towards modesty evidential claims, including claims parsimony and interpretations experiments. To draw conclusions, evidence must be collected from wherever it can found, structured some way, considered holistically an inference to best explanation.

Language: Английский

Citations

0
Modeling DOI
Mike Dacey

Oxford University Press eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 71 - 94

Published: Jan. 26, 2025

Abstract This chapter addresses the challenge of modeling: it is very difficult to model cognitive processes in precise ways that are necessary for models make specific predictions can be tested. As a result, comparative psychology too often verbally expressed and underspecified. The suggests one possible way forward: more modest interpretation associative models. explained using work on causal reasoning rats. If we take provide only abstract, partial descriptions process they describe, serve as bridges from data. scaffold developing precise, perhaps mathematical, In general, should expect any model, full understanding psychological will require multiple different types.

Language: Английский

Citations

0