Bridging Minds and Machines: The Recent Advances of Brain-Computer Interfaces in Neurological and Neurosurgical Applications

World Neurosurgery, Journal Year: 2024, Volume and Issue: 189, P. 138 - 153

Published: May 22, 2024

Brain-computer interfaces (BCIs), a remarkable technological advancement in neurology and neurosurgery, mark significant leap since the inception of electroencephalography 1924. These effectively convert central nervous system signals into commands for external devices, offering revolutionary benefits to patients with severe communication motor impairments due myriad neurological conditions like stroke, spinal cord injuries, neurodegenerative disorders. BCIs enable these individuals communicate interact their environment, using brain operate environmental control. This technology is especially crucial those completely locked in, providing lifeline where other methods fall short. The advantages are profound, autonomy an improved quality life disabilities. They allow direct interaction various devices prostheses, bypassing damaged or nonfunctional neural pathways. However, challenges persist, including complexity accurately interpreting signals, need individual calibration, ensuring reliable, long-term use. Additionally, ethical considerations arise regarding autonomy, consent, potential dependence on technology. Despite challenges, represent transformative development neurotechnology, promising enhanced patient outcomes deeper understanding brain-machine interfaces.

Language: Английский

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Advances and Challenges in Closed Loop Therapeutics: From Signal Selection to Optogenetic Techniques

Journal of Biomedical and Sustainable Healthcare Applications, Journal Year: 2024, Volume and Issue: unknown, P. 73 - 83

Published: Jan. 5, 2024

The main objective of this paper is to develop closed-loop therapeutic systems by reviewing various neurological disorders. We propose a system that incorporates biosensor, controller, and infusion pump provide feedback management medicine delivery. To address the specific requirements medication called Dox, they made precise adjustments system's functioning. device biosensor capable real-time assessment levels in bloodstream. method utilizes aptamer probes have been labeled with an electrochemical tag. When these connect drug target, undergo reversible change shape, leading modification redox current. A little quantity blood consistently extracted from animal's circulatory inside microfluidic device, which used for measurement. examines challenges seizure detection use advanced learning algorithms classification methods enhance real- time systems. Following successful optogenetic techniques epilepsy models, authors discuss potential technologies controlling brain activity.

Language: Английский

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Integrating AI in fighting advancing Alzheimer: diagnosis, prevention, treatment, monitoring, mechanisms, and clinical trials

Current Opinion in Structural Biology, Journal Year: 2024, Volume and Issue: 87, P. 102857 - 102857

Published: June 5, 2024

Language: Английский

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Training Profiles, Efficacy Perceptions, and Outcomes of Non-Invasive Neuromodulation: An Exploratory Study Among Practitioners

Psychiatry International, Journal Year: 2025, Volume and Issue: 6(1), P. 18 - 18

Published: Feb. 17, 2025

Advances in non-invasive neuromodulation (NM) have enabled practitioners to modulate neural activity safely, offering a promising approach treating neuropsychiatric and neurological conditions. This study aimed analyze the training profiles of NM assess their perceptions NM’s clinical efficacy, safety, patient satisfaction. An online survey was conducted among 117 various healthcare fields, using Clinical Global Impression (CGI) scale gauge outcomes. The findings indicate that 99.13% perceive as effective, with high rates improvement quality life symptom management. underscores importance standardized protocols enhance therapeutic

Language: Английский

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A comprehensive review of neurotransmitter modulation via artificial intelligence: A new frontier in personalized neurobiochemistry

Computers in Biology and Medicine, Journal Year: 2025, Volume and Issue: 189, P. 109984 - 109984

Published: March 14, 2025

Language: Английский

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Skin Lesions as Signs of Neuroenhancement in Sport

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(3), P. 315 - 315

Published: March 17, 2025

Background: Neuroenhancement in sports, through pharmacological and non-pharmacological methods, is a complex highly debated topic with no definitive regulatory framework established by the World Anti-Doping Agency (WADA). The hypothesis that dermatological changes could serve as observable biomarkers for neurodoping introduces novel promising approach to detecting understanding physiological impacts of cognitive enhancers athletes. As methods become increasingly sophisticated, developing objective, reliable, non-invasive detection strategies imperative. Utilizing signs diagnostic tool internal neurophysiological offer critical insights into safety, fairness, ethical considerations enhancement competitive sports. A systematic correlation between skin manifestations, timeline practices, intensity provide healthcare professionals valuable tools monitoring athletes’ health ensuring strict compliance anti-doping regulations. Methods: Due limited body research on this topic, review literature was conducted, spanning from 2010 31 December 2024, using databases such PubMed, Science Direct, Google Scholar. This study followed 2020 PRISMA guidelines included English-language articles published within specified period, focusing lesions adverse reactions neuroenhancement methods. employed targeted keywords, including “skin AND rivastigmine”, galantamine”, donepezil”, memantine”, transcranial direct electrical stimulation”. Given scarcity studies directly addressing search criteria were broadened include associated brain stimulation. Eighteen relevant identified analyzed. Results: rivastigmine patches most used method neuroenhancement, pruritic (itchy) frequent effect. Donepezil fewer primarily non-pruritic reactions. Among current stimulation (tDCS) notably linked burns, due inadequate electrode–skin contact, prolonged exposure, or excessive intensity. These findings suggest specific manifestations potential indicators practices Conclusions: Although demonstrate distinctive side effects might signal neurodoping, lack robust clinical data involving athletes limits ability draw conclusions. Athletes who engage without medical supervision are at an elevated risk systemic Skin lesions, therefore, represent early marker inappropriate use overuse cognitive-enhancing drugs neuromodulation therapies. emphasize need focused establish validated neurodoping. contribute significantly ongoing neuroethical discourse regarding legitimacy safety

Language: Английский

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The neuroplastic brain: current breakthroughs and emerging frontiers

Brain Research, Journal Year: 2025, Volume and Issue: unknown, P. 149643 - 149643

Published: April 1, 2025

Language: Английский

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Electrical and Magnetic Neuromodulation Technologies and Brain-Computer Interfaces: Ethical Considerations for Enhancement of Brain Function in Healthy People – A Systematic Scoping Review

Stereotactic and Functional Neurosurgery, Journal Year: 2024, Volume and Issue: 102(5), P. 308 - 324

Published: July 10, 2024

This scoping review aimed to synthesize the fragmented evidence on ethical concerns related use of electrical and magnetic neuromodulation technologies, as well brain-computer interfaces for enhancing brain function in healthy individuals, addressing gaps understanding spurred by rapid technological advancements ongoing debates.

Language: Английский

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Advancements in Understanding and Classifying Chronic Orofacial Pain: Key Insights from Biopsychosocial Models and International Classifications (ICHD-3, ICD-11, ICOP)

Biomedicines, Journal Year: 2023, Volume and Issue: 11(12), P. 3266 - 3266

Published: Dec. 9, 2023

In exploring chronic orofacial pain (COFP), this review highlights its global impact on life quality and critiques current diagnostic systems, including the ICD-11, ICOP, ICHD-3, for their limitations in addressing COFP's complexity. Firstly, study outlines burden of importance distinguishing between different types effective treatment. It then delves into specific challenges diagnosing COFP, emphasizing need a more nuanced approach that incorporates biopsychosocial model. This critically examines existing classification highlighting fully capturing multifaceted nature. advocates integration these systems with DSM-5's Somatic Symptom Disorder code, proposing unified, multidisciplinary approach. recommendation aims to improve coding standardization acknowledge complex interplay biological, psychological, social factors COFP. conclusion, here, we highlight comprehensive, universally applicable system Such would enable accurate diagnosis, streamline treatment strategies, enhance communication among healthcare professionals. advancement holds potential significant contributions research patient care challenging field, offering broader perspective scientists across disciplines.

Language: Английский

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The Use of Transcranial Magnetic Stimulation in Attention Optimization Research: A Review from Basic Theory to Findings in Attention-Deficit/Hyperactivity Disorder and Depression

Life, Journal Year: 2024, Volume and Issue: 14(3), P. 329 - 329

Published: Feb. 29, 2024

This review explores the pivotal role of attention in everyday life, emphasizing significance studying attention-related brain functions. We delve into development methodologies for investigating and highlight crucial neuroimaging transcranial magnetic stimulation (TMS) advancing research. Attention optimization theory is introduced to elucidate neural basis attention, identifying key regions circuits involved processes. The further neuroplasticity, shedding light on how dynamically adapts changes optimize attention. A comprehensive overview TMS provided, elucidating principles applications this technique affecting activity through field stimulation. application research discussed, outlining it can be employed regulate networks. clinical are explored attention-deficit/hyperactivity disorder (ADHD) depression. emerges as an effective treatment ADHD, showcasing its potential addressing disorders. Additionally, paper emphasizes efficacy technology a method regulating depression, underlining versatility therapeutic settings. In conclusion, underscores interdisciplinary approach research, integrating neuroimaging, TMS. presented findings contribute our understanding mechanisms promising synthesis theoretical practical insights aims propel advancements applications.

Language: Английский

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