Comprehensive and critical view on the anti-inflammatory and immunomodulatory role of natural phenolic antioxidants
European Journal of Medicinal Chemistry,
Journal Year:
2023,
Volume and Issue:
265, P. 116075 - 116075
Published: Dec. 21, 2023
Language: Английский
Association between consumption of flavonol and its subclasses and chronic kidney disease in US adults: an analysis based on National Health and Nutrition Examination Survey data from 2007–2008, 2009–2010, and 2017–2018
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: June 18, 2024
Background
There
is
little
research
on
the
relationship
between
flavonol
consumption
and
chronic
kidney
disease
(CKD).
This
study
aimed
to
examine
link
risk
of
CKD
among
US
adults,
using
data
from
2007–2008,
2009–2010
2017–2018
National
Health
Nutrition
Examination
Survey
(NHANES).
Methods
A
cross-sectional
approach
was
used,
drawing
three
NHANES
cycles.
The
participants
in
this
assessed
a
48
h
dietary
recall
interview.
diagnosed
based
an
estimated
glomerular
filtration
rate
below
60
mL/min/1.73
m
2
or
urine
albumin-to-creatinine
ratio
30
mg/g
higher.
Results
Compared
lowest
quartile
intake
(Q1),
odds
ratios
for
were
0.598
(95%
CI:
0.349,
1.023)
second
(Q2),
0.679
0.404,
1.142)
third
(Q3),
0.628
0.395,
0.998)
fourth
(Q4),
with
p
value
trend
significance
0.190.
In
addition,
there
significant
isorhamnetin
intake,
decreasing
0.860
0.546,
1.354)
quartile,
0.778
0.515,
1.177)
0.637
(
=
0.013).
Conclusion
Our
analysis
spanning
2009–2010,
suggests
that
high
flavonol,
especially
isorhamnetin,
might
be
linked
lower
adults.
These
findings
offer
new
avenues
exploring
strategies
managing
CKD.
Language: Английский
Associations between polyphenol intake, cardiometabolic risk factors and metabolic syndrome in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
Journal of Nutrition,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 1, 2024
Language: Английский
Effect of Dietary Flavonoids on Circadian Syndrome: A Population-Based Cross-Sectional Study
Metabolic Syndrome and Related Disorders,
Journal Year:
2024,
Volume and Issue:
22(5), P. 385 - 393
Published: March 7, 2024
Altering
the
dietary
patterns
can
potentially
decrease
likelihood
of
metabolic
syndrome
and
circadian
(CircS),
but
it
remains
unclear
which
types
flavonoid
compounds
are
responsible
for
these
effects,
particularly
among
nationally
representative
populations.
Thus,
we
conducted
a
cross-sectional
study
to
investigate
impact
intake
on
CircS.
Language: Английский
Association between dietary intake of flavonoid and chronic kidney disease in US adults: Evidence from NHANES 2007-2008, 2009-2010, and 2017-2018
Peijia Liu,
No information about this author
Wujian Peng,
No information about this author
Feng Hu
No information about this author
et al.
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(8), P. e0309026 - e0309026
Published: Aug. 27, 2024
Background
Studies
investigating
the
relationship
between
flavonoid
intake
and
chronic
kidney
disease
(CKD)
are
limited.
This
study
investigated
association
daily
CKD
in
US
adults
by
using
data
for
2007–2008,
2009–2010,
2017–2018
from
National
Health
Nutrition
Examination
Survey
(NHANES)
database.
Methods
employed
a
cross-sectional
design
used
three
cycles
of
continuous
NHANES:
2017–2018.
NHANES
researchers
collected
related
to
consumption
various
food
beverages
participants
employing
24-h
dietary
recall
questionnaires.
is
defined
as
an
estimated
glomerular
filtration
rate
<
60
mL/min/1.73m
2
or
urine
albumin-to-creatinine
ratio
≥
30
mg/g.
Results
The
odds
ratios
(OR)
risk
second
(Q2),
third
(Q3),
fourth
(Q4)
quartiles
total
intake,
compared
with
that
first
(Q1)
quartile,
were
0.780
(95%
CI:
0.600,
1.015),
0.741
0.573,
0.957),
0.716
0.554,
0.925),
respectively
(with
P
value
trend
0.040).
According
restricted
cubic
spline
analysis,
exhibited
non-linear
(P
0.001).
Conclusion
Our
findings
suggest
potential
J-shaped
was
observed
risk,
inflection
point
at
69.58
mg/d.
indicates
moderate
flavonoids
may
confer
renal
benefits
which
offer
novel
strategies
treatment.
Language: Английский
The association between dietary polyphenol intake and the odds of metabolic syndrome
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Oct. 26, 2024
Oxidative
stress
plays
a
role
in
the
pathophysiology
of
metabolic
syndrome
(MetS),
and
one
most
important
features
polyphenols
is
their
antioxidant
properties.
However,
there
no
universal
consensus
on
effectiveness
treating
Mets.
Therefore,
present
study
aimed
to
investigate
association
between
MetS
an
Iranian
sample.
This
cross-sectional
was
conducted
adult
population
sample
from
Shiraz,
southern
Iran.
calculated
using
criteria
Adult
Treatment
Panel
III
(ATP
III),
which
defines
as
presence
three
or
more
specified
risk
factors.
A
validated
food
frequency
questionnaire
(FFQ)
used
measure
participant's
intake.
The
polyphenol
intake
odds
its
components
assessed
logistic
regression.
In
both
univariate
multivariate
models,
not
significant.
after
adjusting
for
potential
confounders
model,
each
unit
change
flavonol,
flavanone
isoflavones
associated
with
lower,
higher,
higher
MetS,
respectively
(flavonols:
ratio
(OR)
=
0.926,
95%
confidence
interval
(CI)
0.891–0.963,
P
<
0.001—flavanones:
OR
1.007,
CI:
1.001–1.014,
0.034—isoflavones:
4.920,
1.057–22.894,
0.042).
Additionally,
significant
found
components.
confounders,
observed
lower
high
waist
circumference
(OR
0.998,
0.996–0.999,
0.032).
did
reveal
overall
MetS.
certain
subclasses
appear
be
likelihood
Language: Английский
Association of Dietary Flavonoid Intake with Serum Cotinine Levels in the General Adult Population
Nutrients,
Journal Year:
2023,
Volume and Issue:
15(19), P. 4126 - 4126
Published: Sept. 25, 2023
Cotinine,
the
primary
metabolite
of
nicotine,
can
be
utilized
as
a
marker
for
active
smoking
and
an
indicator
exposure
to
secondhand
smoke.
However,
direct
relationship
between
dietary
flavonoid
intake
serum
cotinine
levels
remains
subject
ongoing
investigation.
In
this
study,
we
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
2007–2010
2017–2018
assess
association
in
adults
through
multiple
linear
regression
analysis.
A
weighted
quantile
sum
(WQS)
model
was
used
mixture
six
flavonoids
with
adults,
which
could
represent
overall
effect
flavonoids.
We
also
conducted
stratified
analyses
by
smoke
status
explore
associations
different
levels.
total
14,962
were
included
study.
Compared
group
lowest
intake,
second
(β
=
−0.29
[−0.44,
−0.14]),
third
−0.41
[−0.58,
−0.24]),
highest
groups
−0.32
[−0.49,
−0.16])
inversely
related
after
adjusting
full
model.
An
RCS
showed
that
when
less
than
99.61
mg/day,
there
negative
cotinine.
The
WQS
significantly
negatively
correlated
−0.54
[−0.61,
−0.46],
p
<0.01),
anthocyanins
having
greatest
(weights
32.30%).
Our
findings
imply
significant
correlation
among
adults.
consumption
combination
consistently
linked
lower
levels,
displaying
most
pronounced
impact.
Language: Английский
Dietary anthocyanin is associated with a lower prevalence of hyperuricemia independently of metabolic syndrome among females: Results from NHANES 2007–2010 and 2017–2018
Xin Li,
No information about this author
Hao Yang,
No information about this author
Peiyu Zhang
No information about this author
et al.
International Journal of Rheumatic Diseases,
Journal Year:
2024,
Volume and Issue:
27(5)
Published: May 1, 2024
Abstract
Objective
Known
for
anti‐inflammatory
and
antioxidant
properties,
flavonoid
has
phytoestrogenic
effects,
but
it
is
unclear
whether
its
role
in
hyperuricemia
metabolic
syndrome
(MetS)
differs
by
gender.
Moreover,
given
the
strong
association
between
MetS,
we
aimed
to
explore
a
protective
factor
hyperuricemia,
independently
of
different
genders.
Methods
Data
2007–2010
2017–2018
were
obtained
from
National
Health
Nutrition
Examination
Survey
(NHANES)
Food
Nutrient
Database
Dietary
Studies
(FNDDS).
To
assess
among
flavonoid,
multivariate
logistic
regression
subgroup
analyses
conducted.
Besides,
investigate
was
independent
models
further
conducted
MetS
females
with
after
excluding
MetS.
Result
Among
5356
females,
anthocyanin
intake
inversely
associated
prevalence
(Q4
vs.
Q1:
OR
0.49,
95%
CI
0.31
0.76),
0.68,
0.50
0.93).
Furthermore,
showed
beneficial
aged
40
59
years
menopausal.
However,
5104
males,
no
significant
observed
adjustment
covariates
0.81,
0.56
1.18).
While
372
found
0.88,
2.49).
Meanwhile,
3335
there
still
lower
0.38,
0.17
0.85).
Conclusion
females.
Foods
rich
should
be
emphasized
especially
those
menopausal,
which
may
potential
significance
prevention
hyperuricemia.
Language: Английский
Flavonoids intake and weight-adjusted waist index: insights from a cross-sectional study of NHANES
Shuang Zu,
No information about this author
Meiling Yang,
No information about this author
Xiude Li
No information about this author
et al.
Frontiers in Nutrition,
Journal Year:
2024,
Volume and Issue:
11
Published: June 18, 2024
This
study
conducted
data
on
15,446
adults
to
explore
the
impact
of
flavonoids
weight-adjusted
waist
index
(WWI).
was
a
nationwide
cross-sectional
among
US
aged
20
years
or
older.
Dietary
intake
assessed
through
24-h
recall
questionnaire.
WWI
calculated
by
dividing
circumference
(WC)
square
root
weight.
We
utilized
weighted
generalized
linear
regression
evaluate
association
between
and
WWI,
restricted
cubic
splines
(RCS)
potential
non-linear
relationships.
Our
findings
indicated
that
individuals
with
lower
experienced
notable
increase
in
their
consumption
total
flavonoids,
flavanones,
flavones,
flavan-3-ols,
anthocyanidins
(
β
(95%
CI);
−0.05(−0.09,
−0.01);
−0.07(−0.13,
0.00);
−0.07(−0.11,
−0.02);
−0.06(−0.11,
−0.13(−0.18,
−0.08),
respectively),
exception
flavonols
isoflavones.
Additionally,
flavonols,
isoflavones,
flavan-3-ols
had
relationship
(all
P
for
non-linearity
<
0.05).
Furthermore,
effect
varied
race
interaction
=
0.011),
gender
0.038),
poverty
status
0.002).
These
suggested
might
prevent
abdominal
obesity,
but
further
prospective
studies
are
requested
before
dietary
recommendation.
Language: Английский
Association of Dietary Vitamin C Intake with the Risk of Metabolic Syndrome Among Adults: NHANES 2007–2018
Xinyi Yu,
No information about this author
Jian Zhu,
No information about this author
Zhaonv Xu
No information about this author
et al.
Metabolic Syndrome and Related Disorders,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 28, 2024
There
has
been
discussion
over
the
association
between
vitamin
C
intake
and
risk
of
metabolic
syndrome
(MetS).
This
study
examined
relationship
dietary
MetS
in
a
sizable
adult
American
population.
Language: Английский