Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: Dec. 16, 2024
Oxidative
stress
has
an
important
role
in
type
2
diabetes
(T2D).
balance
score
(OBS)
is
emerging
assessment
of
dietary
and
lifestyle
oxidative
balance.
We
aimed
to
explore
the
association
OBS
with
cardiovascular
disease
(CVD)
all-cause
CVD
mortality
T2D
population
through
NHANES
1999-2018.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 15, 2024
Abstract
Background
The
oxidative
stress
theory
of
aging
is
one
the
prominent
theories
in
field
research.
Oxidative
Balance
Score
(OBS)
serves
as
a
comprehensive
tool
for
evaluating
effects
different
diets
and
lifestyles
on
oxidative/antioxidant
system,
however,
its
correlation
with
biological
remains
ambiguous.
We
thus
conducted
this
study
to
explore
relationship
between
OBS
American
adults
using
quantitative
measures.
Methods
cross-sectional
NHANES
1999–2018
database.
examined
several
indicators,
including
age,
phenotypic
telomere
length,
serum
klotho
levels.
A
weighted
multiple
linear
regression
model
smoothed
fitted
curves
were
employed
analyze
nonlinear
markers.
Additionally,
quantile
was
utilized
further
their
associations.
Results
significant
negative
found
both
ages,
whereas
positive
observed
length
Upon
comparing
highest
tertile
lowest
tertile,
fully
adjusted
β
values
−
0.663
(-0.867,
-0.458),
-1.792
(-2.190,
-1.393),
32.332
(8.193,
56.471)
klotho,
respectively.
Notably,
[0.031
(0.007,
0.056)]
only
partially
model.
consistent
individuals
aged
over
60
years.
In
regression,
OBS,
DOBS,
LOBS
most
at
0.93
percentile
age
0.95
age.
Moreover,
concentration
exhibited
across
all
quantiles,
strongest
percentile.
Conclusions
Our
suggests
dose-response
aging,
indicating
adopting
an
antioxidant-rich
diet
lifestyle
may
yield
beneficial
aging.
These
findings
offer
theoretical
insights
into
strategies
prevention.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 29, 2024
Abstract
The
American
Heart
Association
updated
the
cardiovascular
health
(CVH)
assessment
tool,
Life's
Essential
8
(LE8).
Metabolic
dysfunction-associated
steatotic
liver
disease
(MASLD)
is
now
most
common
chronic
worldwide
and
associated
with
excessive
mortality
risk.
10050
participants
MASLD
were
included
from
NHANES
2005–2018.
LE8
was
assessed
by
combining
4
behaviors
factors,
0–49
being
low
CVH,
50–79
moderate
80–100
high
CVH.
In
fully
adjusted
model,
each
point
increase
in
score
a
2.7%,
1.6%
decrease
all-cause,
CVD,
cancer
risk,
respectively,
people
MASLD.
Compared
to
moderate/high
CVH
negatively
outcomes,
while
factors
lost
significant
association
mortality.
Most
of
associations
showed
dose-response
associations,
except
for
all-cause
CVD
Race/ethnicity
income-poverty
ratio
significantly
influenced
between
mortality.LE8
lower
Assessment
may
contribute
targeted
healthy
lifestyle
factor
modification
prevent
excess
Frontiers in Endocrinology,
Journal Year:
2024,
Volume and Issue:
15
Published: Dec. 16, 2024
Oxidative
stress
has
an
important
role
in
type
2
diabetes
(T2D).
balance
score
(OBS)
is
emerging
assessment
of
dietary
and
lifestyle
oxidative
balance.
We
aimed
to
explore
the
association
OBS
with
cardiovascular
disease
(CVD)
all-cause
CVD
mortality
T2D
population
through
NHANES
1999-2018.
