Evaluating the Therapeutic Efficacy of Lactobacillus Strains in the Management of Ulcerative Colitis: An Overview of Recent Advances DOI

Shaghayegh Rezaei,

Elnaz Ghorbani,

Abdulridha Mohammed Al-Asady

et al.

Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 31(6), P. 413 - 421

Published: Oct. 14, 2024

Ulcerative Colitis (UC) known as a sub-category of Inflammatory Bowel Diseases (IBD) is longterm condition that causes inflammation, irritation, and ulcers in the colon rectum. Though precise pathogenesis UC not fully understood yet, impaired immune responses imbalanced intestinal microbiome composition have been regarded two main key players colitis pathobiology. As conventional treatments are challenged with limitations side effects, finding new therapeutic approach has gained increasing attention. Probiotic bacteria multifunctional health-promoting properties considered novel options. There strong evidence indicating probiotics exert their effects mostly by regulating system restoring gut homeostasis. These results validate rationale behind clinical application management whether prescribed alone or combination therapy. This article explores UC, concentrating on influence dysregulation imbalances. Also, it reviews recent <i>in vitro, vivo</i>, studies demonstrated efficacy <i>Lactobacillus</i> species decreasing symptoms modifying responses, microbiota balance, promoting barrier function.

Language: Английский

Investigating the Knowledge of Prebiotics, Probiotics, and Synbiotics That May Help to Improve the Gut-Organ Axis Function in Middle-Aged and Older Adults DOI Open Access

Desiree Fermin,

Sahar G. Alshammari,

Joao Morgadinho

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 16, 2024

The use of gut biotics, including probiotics, prebiotics, and synbiotics, has shown substantial potential in the management various health conditions possibly through gut-organ axis. role biotics modulating gut-brain axis is becoming evident with more research focusing on this intervention. Improvement function possible by using food-related products called biotics. However, there limited comprehension knowledge these intestinal or Our aim was to recognize gaps assess improvement understanding following an education

Language: Английский

Citations

0
Evaluating the Therapeutic Efficacy of Lactobacillus Strains in the Management of Ulcerative Colitis: An Overview of Recent Advances DOI

Shaghayegh Rezaei,

Elnaz Ghorbani,

Abdulridha Mohammed Al-Asady

et al.

Current Pharmaceutical Design, Journal Year: 2024, Volume and Issue: 31(6), P. 413 - 421

Published: Oct. 14, 2024

Ulcerative Colitis (UC) known as a sub-category of Inflammatory Bowel Diseases (IBD) is longterm condition that causes inflammation, irritation, and ulcers in the colon rectum. Though precise pathogenesis UC not fully understood yet, impaired immune responses imbalanced intestinal microbiome composition have been regarded two main key players colitis pathobiology. As conventional treatments are challenged with limitations side effects, finding new therapeutic approach has gained increasing attention. Probiotic bacteria multifunctional health-promoting properties considered novel options. There strong evidence indicating probiotics exert their effects mostly by regulating system restoring gut homeostasis. These results validate rationale behind clinical application management whether prescribed alone or combination therapy. This article explores UC, concentrating on influence dysregulation imbalances. Also, it reviews recent <i>in vitro, vivo</i>, studies demonstrated efficacy <i>Lactobacillus</i> species decreasing symptoms modifying responses, microbiota balance, promoting barrier function.

Language: Английский

Citations

0