Associations between oxidative balance score and chronic kidney disease events in type 2 diabetes mellitus patients: a cross‑sectional study
Yunhe Ding,
No information about this author
Liwen Liu,
No information about this author
Zhen Feng
No information about this author
et al.
Research Square (Research Square),
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 14, 2025
Abstract
The
Oxidative
Balance
Score
(OBS)
serves
as
a
comprehensive
metric
that
amalgamates
17
dietary
and
lifestyle
elements
to
evaluate
antioxidant
status.
Thi
research
aims
investigate
the
association
between
OBS
prevalence
of
chronic
kidney
disease
(CKD)
in
individuals
diagnosed
with
type
2
diabetes
mellitus
(T2DM).
This
cross-sectional
study
included
data
from
National
Health
Nutrition
Examination
Survey
(NHANES)
conducted
2007
2018.
CKD
was
determined
using
albumin-to-creatinine
ratio(ACR)and
estimated
glomerular
filtration
rate
(eGFR).
Patients
were
grouped
into
low,
moderate,
high-risk
categories
based
on
their
risk
levels.
variable
transformed
continuous
format
quartiles
for
subsequent
analysis.
Weighted
multivariable
logistic
regression
restricted
cubic
spline
models
employed
examine
relationship.
Subgroup
analyses
interaction
tests
assessed
findings'
robustness.
results
indicated
negative
correlation
risk.
Individuals
higher
exhibited
decreased
(OR
0.69,
95%
CI:
0.57–0.85,
P
=
0.0003).
A
notable
identified
among
low-risk
moderate-risk
groups.
subgroup
analysis
stable,
no
significant
interactions
detected
subgroups.
Increased
levels
correlated
CKD.
Improving
capacity
through
modifications
enhance
may
serve
an
effective
strategy
prevention.
Language: Английский
The interaction between sleep patterns and oxidative balance scores on the risk of cognitive function decline: Results from the national health and nutrition examination survey 2011–2014
Taiwei Lou,
No information about this author
Zhiru Zhao,
No information about this author
Huaidong Du
No information about this author
et al.
PLoS ONE,
Journal Year:
2024,
Volume and Issue:
19(12), P. e0313784 - e0313784
Published: Dec. 27, 2024
Background
Unhealthy
sleep
and
exposures
to
oxidative
factors
are
both
associated
with
poor
cognitive
performance
(PCP),
but
limited
evidence
has
been
found
regarding
the
relationship
between
patterns
factor
independently
or
jointly
risk
of
PCP.
Methods
We
analyzed
data
from
2249
adults
aged
≥60
years
in
National
Health
Nutrition
Examination
Survey
(
NHANES
)
database
(2011–2014).
Self-reported
questionnaires
were
used
collect
on
duration
disorder,
categorizing
into
three
groups
based
responses:
short
(6
hours
less
per
night),
normal
(7–8
long
(9
more
night).
Sleep
disorder
categorized
two
groups:
non-sleep
disorder.
Oxidative
balance
score
OBS
was
calculated
20
stress
related
diet
lifestyle
factors,
higher
scores
indicating
greater
antioxidant
exposures.
Survey-based
multivariable
adjusted
regression
analyses
conducted
examine
associations
alone
combination
overall
PCP
risks.
Results
Compared
group,
group
had
a
(DSST<34)
(OR
=
1.91,
95%
CI
1.05–3.48,
P
0.021);
while
negatively
correlated
[Q4
vs
Q1
0.50,
0.29–0.92,
0.004)].
There
an
interaction
effect
(sleep
duration,
disturbances)
(P
0.002).
Further
stratified
analysis
showed
that
individuals
no
disturbances,
exposures,
compared
pro-oxidant
reduced
low
function
occurrence.
Conclusions
In
older
populations,
unhealthy
(especially
excessive
duration)
increase
decline.
Healthy
habits
rich
crucial
for
protecting
adults.
Language: Английский