European journal of medical research, Journal Year: 2025, Volume and Issue: 30(1)

Published: Feb. 24, 2025

To investigate the relationship between geriatric nutritional risk index (GNRI) and sepsis in elderly critically ill patients. We extracted data from MIMIC-IV database for patients aged 65 older who were first-time admissions to Intensive Care Unit. The GNRI, derived serum albumin, height, weight, served as exposure variable. main outcome was occurrence of sepsis. utilized multivariable logistic regression evaluate association GNRI Additionally, we employed restricted cubic splines potential nonlinear incidence study included 3,535 patients, with 2,005 (56.7%) developing Septic had significantly lower values (median: 99 vs. 101, P = 0.021) a higher prevalence malnutrition (GNRI ≤ 98) (47.5% 43.5%, 0.018). analysis employing identified U-shaped (P non-linearity 0.004), an inflection point at 105.4. left this point, negatively associated (OR 0.987, 95% CI 0.978—0.996, 0.005), while right side showed positive correlation 1.011, 1.000—1.022, 0.044). reveals Both low high are increased risk, turning These findings highlight GNRI's utility screening tool identifying ICU

Language: Английский