Association between stress hyperglycemia ratio and contrast-induced nephropathy in ACS patients undergoing PCI: a retrospective cohort study from the MIMIC-IV database DOI Creative Commons
Yan-Long Zhao, Yuanyuan Zhao, Shuai Wang

et al.

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 25, 2025

Contrast-induced nephropathy (CIN) is a significant complication in acute coronary syndrome (ACS) patients undergoing percutaneous intervention (PCI). The role of the stress hyperglycemia ratio (SHR) as predictor CIN and mortality these remains unclear warrants investigation. To assess relationship between SHR CIN, well its impact on short-term ACS PCI. We conducted retrospective cohort study using MIMIC-IV database, including 552 patients. was calculated admission glucose to estimated average from hemoglobin A1c. defined ≥ 0.5 mg/dL or 25% increase serum creatinine within 48 h Logistic regression spline models were used analyze association while Kaplan–Meier curves assessed 30-day mortality. Higher levels independently associated with increased risk (OR 2.36, 95% CI: 1.56–3.57, P < 0.0001). A J-shaped observed, rising sharply when exceeded 1.06. also higher (P Subgroup analysis revealed stronger SHR-CIN non-diabetic an independent It offers potential for stratification clinical decision-making, especially

Language: Английский

Association between stress hyperglycemia ratio and contrast-induced nephropathy in ACS patients undergoing PCI: a retrospective cohort study from the MIMIC-IV database DOI Creative Commons
Yan-Long Zhao, Yuanyuan Zhao, Shuai Wang

et al.

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 25, 2025

Contrast-induced nephropathy (CIN) is a significant complication in acute coronary syndrome (ACS) patients undergoing percutaneous intervention (PCI). The role of the stress hyperglycemia ratio (SHR) as predictor CIN and mortality these remains unclear warrants investigation. To assess relationship between SHR CIN, well its impact on short-term ACS PCI. We conducted retrospective cohort study using MIMIC-IV database, including 552 patients. was calculated admission glucose to estimated average from hemoglobin A1c. defined ≥ 0.5 mg/dL or 25% increase serum creatinine within 48 h Logistic regression spline models were used analyze association while Kaplan–Meier curves assessed 30-day mortality. Higher levels independently associated with increased risk (OR 2.36, 95% CI: 1.56–3.57, P < 0.0001). A J-shaped observed, rising sharply when exceeded 1.06. also higher (P Subgroup analysis revealed stronger SHR-CIN non-diabetic an independent It offers potential for stratification clinical decision-making, especially

Language: Английский

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