
Asian Journal of Surgery, Journal Year: 2023, Volume and Issue: 47(2), P. 1143 - 1145
Published: Nov. 29, 2023
Language: Английский
Asian Journal of Surgery, Journal Year: 2023, Volume and Issue: 47(2), P. 1143 - 1145
Published: Nov. 29, 2023
Language: Английский
Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown
Published: Sept. 18, 2023
Abstract Background Cytokine-like protein 1 (CYTL1) is ubiquitously expressed in multiple human cancers, including gastric cancer (GC). However, its physiological role GC unknown. Herein, we elucidated the importance of CYTL1 and assessed association with progression. Methods The Cancer Genome Atlas (TCGA) was used to obtain clinical data for patients. Next, investigated associations among expression level, pathological features, patient prognosis. Finally, examined relationships immune cell invasion (CI), Results level elevated tissues compared surrounding normal tissues. Moreover, enhanced GCs intricately linked worse Based on univariate multivariate Cox regression analyses, along age, residual tumor status, N stage, primary therapeutic outcome, an independent indicator disease-specific survival (DSS), overall (OS), progression-free interval (PFI) Furthermore, associated infiltration pDCs, mast cells, macrophages, DCs, Tem NK Th2 Th17 cells. Using gene set enrichment analysis (GSEA), revealed that proliferation (CP) glycolytic network. knockdown lines drastically reduced CP, migration (CM), CI both vitro vivo studies. Conclusion correlates progression glycolysis, indicating it may be a strong prognostic GC.
Language: Английский
Citations
0International Urology and Nephrology, Journal Year: 2023, Volume and Issue: 56(2), P. 483 - 497
Published: Sept. 23, 2023
Language: Английский
Citations
0Asian Journal of Surgery, Journal Year: 2023, Volume and Issue: 47(1), P. 549 - 551
Published: Sept. 28, 2023
Citations
0Asian Journal of Surgery, Journal Year: 2023, Volume and Issue: 47(1), P. 818 - 820
Published: Nov. 7, 2023
Language: Английский
Citations
0Asian Journal of Surgery, Journal Year: 2023, Volume and Issue: 47(2), P. 1143 - 1145
Published: Nov. 29, 2023
Language: Английский
Citations
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