COVID-19–sensitive tumour response: 2-year assessment of the SARS-CoV-2 humoral response in cancer patients in oncology hospital in Poland DOI Creative Commons
Piotr Kosiorek, Bożena Mikołuć, Samuel Stróż

et al.

Cancer Immunology Immunotherapy, Journal Year: 2024, Volume and Issue: 74(1)

Published: Dec. 21, 2024

Abstract Vaccination has been considered the most crucial defence against viral infections, including SARS-CoV-2. Numerous reports have demonstrated effectiveness of above vaccines in oncological patients. It also proven that, apart from vaccinations and therapy, course cancer process itself influences magnitude humoral response, especially people after infection with The phenomenon we observe seems to confirm presence a "natural" potential patient's body, this case, directed pathogen. A "stronger" antiviral response explains asymptomatic SARS-CoV-2 some To what extent weakened anticancer these patients remains an open question. Objective This study aimed answer question about impact on vaccinated COVID-19. Material methods One thousand six hundred sixty-eight were observed. Over 2 years, 5,082 IgG IgM antibody samples determined. concentration antibodies was assessed groups patients: those undergoing therapy contracting COVID-19 vaccination infection. Results obtained results indicate naturally more significant who not undergone such as radiotherapy, chemotherapy, or surgical intervention. observation applies breast, lung, colon, kidney, testicular cancer, although varies significantly depending type cancer. Graphical abstract

Language: Английский

COVID-19–Sensitive Tumour Response – 2-Year Assessment of the SARS-CoV-2 Humoral Response in Cancer Patients in Oncology Hospital in Poland DOI Open Access
Piotr Kosiorek, Bożena Mikołuć, Samuel Stróż

et al.

Published: Jan. 19, 2024

Background: So far, vaccination has been considered the most crucial defense against viral infection, including SARS-CoV-2. Numerous reports have demonstrated effectiveness of above vaccines in oncology patients. It also proven that, apart from vaccinations and oncological therapy, course cancer process itself influences magnitude humoral response, especially people after infection with Objective: This study aimed to answer question about impact on response patients vaccinated SARS-CoV-2 COVID-19. Material methods: 1,668 were observed. Over two years, 5,082 IgG IgM antibody samples determined. The concentration antibodies was assessed three groups patients: those undergoing anticancer therapy contracting COVID-19 infection. Results: obtained results indicate a naturally more significant who not undergone such as radiotherapy, chemotherapy, or surgical intervention. observation applies breast, lung, colon cancer, although varies significantly depending type cancer. Summary: size presence specific directed SARS-CoV-2, IgM, IgG, supply vaccine antigen COVID-19, is an indicator adequate immune protection reinfection. highlights for first time phenomenon increased certain types that are assumed be sensitive initiation which, according generally accepted principles, blocked by we observe seems confirm "natural" defence potential patient's body, this case, pathogen. A "stronger" antiviral explain asymptomatic some remains open what extent weakened these

Language: Английский

Citations

0

COVID-19–Sensitive Tumour Response – 2-year Assessment of the SARS-CoV-2 Humoral Response in Cancer Patients in Oncology Hospital in Poland DOI Creative Commons
Piotr Kosiorek, Bożena Mikołuć, Samuel Stróż

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 13, 2024

Abstract Vaccination has been considered the most crucial defence against viral infection, including SARS-CoV-2. Numerous reports have demonstrated effectiveness of above vaccines in oncology patients. It also proven that, apart from vaccinations and oncological therapy, course cancer process itself influences magnitude humoral response, especially people after infection with The phenomenon we observe seems to confirm presence a "natural" potential patient's body, this case, directed pathogen. A "stronger" antiviral response explains asymptomatic SARS-CoV-2 some To what extent weakened anticancer these patients remains an open question. Objective: This study aimed answer question about impact on vaccinated COVID-19. Material methods: 1,668 were observed. Over two years, 5,082 IgG IgM antibody samples determined. concentration antibodies was assessed groups patients: those undergoing therapy contracting COVID-19 vaccination infection. Results: The obtained results indicate naturally more significant who not undergone such as radiotherapy, chemotherapy, or surgical intervention. observation applies breast, lung, colon, kidney testicular cancer, although varies significantly depending type cancer.

Language: Английский

Citations

0

COVID-19–sensitive tumour response: 2-year assessment of the SARS-CoV-2 humoral response in cancer patients in oncology hospital in Poland DOI Creative Commons
Piotr Kosiorek, Bożena Mikołuć, Samuel Stróż

et al.

Cancer Immunology Immunotherapy, Journal Year: 2024, Volume and Issue: 74(1)

Published: Dec. 21, 2024

Abstract Vaccination has been considered the most crucial defence against viral infections, including SARS-CoV-2. Numerous reports have demonstrated effectiveness of above vaccines in oncological patients. It also proven that, apart from vaccinations and therapy, course cancer process itself influences magnitude humoral response, especially people after infection with The phenomenon we observe seems to confirm presence a "natural" potential patient's body, this case, directed pathogen. A "stronger" antiviral response explains asymptomatic SARS-CoV-2 some To what extent weakened anticancer these patients remains an open question. Objective This study aimed answer question about impact on vaccinated COVID-19. Material methods One thousand six hundred sixty-eight were observed. Over 2 years, 5,082 IgG IgM antibody samples determined. concentration antibodies was assessed groups patients: those undergoing therapy contracting COVID-19 vaccination infection. Results obtained results indicate naturally more significant who not undergone such as radiotherapy, chemotherapy, or surgical intervention. observation applies breast, lung, colon, kidney, testicular cancer, although varies significantly depending type cancer. Graphical abstract

Language: Английский

Citations

0