Concentric remodeling and the metabolic-associated steatotic liver disease in patients with type 1 diabetes: an exploratory study DOI Creative Commons
Klaudia Czarnik, Zbigniew Sablik, Anna Borkowska

et al.

Acta Diabetologica, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Abstract Introduction Diabetic cardiomyopathy in young patients with type 1 diabetes (T1D) usually presents as asymptomatic diastolic heart dysfunction left ventricle (LV) remodeling. Its prevalence seems to be underestimated. One of the factors seemingly influencing LV remodeling is a metabolic-associated steatotic liver disease (MASLD), which was extensively investigated 2 but not T1D. This study aimed describe correlation between MASLD risk and relative wall thickness (RWT) T1D without failure symptoms or treatment. Materials methods Study participants were recruited at inpatient diabetology department, admission order. Patients underwent set laboratory tests echocardiographic examinations. The estimated using fatty index (FLI). Acquired data then statistically analyzed. Results group consisted 55 patients. 25 had RWT > 0.42, suggesting did differ HbA1c, NT-proBNP, HDL, LDL, non-HDL, uric acid concentrations. However, 0.42 higher FLI (40.97 vs. 13.82, p < 0.01) BMI (27.3 22.5, differed transaminase Moreover, significantly mass (85.6 68.2 g/m2) altered mitral ring velocities. In univariable logistic regression, correlated (OR 1.028, = 0.05). optimal cutoff point for predicting 26.38 10.6, 0.04, sensitivity 0.857, specificity 0.657). Conclusions correlates independently metabolic control hypothetically may support recognizing

Language: Английский

Concentric remodeling and the metabolic-associated steatotic liver disease in patients with type 1 diabetes: an exploratory study DOI Creative Commons
Klaudia Czarnik, Zbigniew Sablik, Anna Borkowska

et al.

Acta Diabetologica, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 17, 2024

Abstract Introduction Diabetic cardiomyopathy in young patients with type 1 diabetes (T1D) usually presents as asymptomatic diastolic heart dysfunction left ventricle (LV) remodeling. Its prevalence seems to be underestimated. One of the factors seemingly influencing LV remodeling is a metabolic-associated steatotic liver disease (MASLD), which was extensively investigated 2 but not T1D. This study aimed describe correlation between MASLD risk and relative wall thickness (RWT) T1D without failure symptoms or treatment. Materials methods Study participants were recruited at inpatient diabetology department, admission order. Patients underwent set laboratory tests echocardiographic examinations. The estimated using fatty index (FLI). Acquired data then statistically analyzed. Results group consisted 55 patients. 25 had RWT > 0.42, suggesting did differ HbA1c, NT-proBNP, HDL, LDL, non-HDL, uric acid concentrations. However, 0.42 higher FLI (40.97 vs. 13.82, p < 0.01) BMI (27.3 22.5, differed transaminase Moreover, significantly mass (85.6 68.2 g/m2) altered mitral ring velocities. In univariable logistic regression, correlated (OR 1.028, = 0.05). optimal cutoff point for predicting 26.38 10.6, 0.04, sensitivity 0.857, specificity 0.657). Conclusions correlates independently metabolic control hypothetically may support recognizing

Language: Английский

Citations

0