Metabolites, Journal Year: 2025, Volume and Issue: 15(4), P. 252 - 252
Published: April 6, 2025
Emerging research suggests that the intrauterine environment plays a critical role in predisposing individuals to metabolic syndrome (MetS), constellation of conditions heightens risk for heart disease, stroke, and diabetes. Traditionally linked lifestyle, MetS is now understood be also influenced by fetal exposures. The which child lives offers abundant potential sources can contribute an increased developing various diseases, some cases, these factors avoided. This review integrates findings from both epidemiological experimental underscore impact prenatal factors, including maternal nutrition, obesity, gestational diabetes (GDM), birth size, on subsequent development derangements offspring, particularly during puberty. progression genetic epigenetic studies has enlightened pathophysiology starting period continuing into early life. By examining data studies, this article elucidates influences underlying mechanisms pathogenesis MetS. updated understanding link between future health comorbidities will draw attention care prevention serious diseases adulthood.
Language: Английский