International Immunopharmacology, Journal Year: 2024, Volume and Issue: 146, P. 113881 - 113881
Published: Dec. 24, 2024
Language: Английский
International Immunopharmacology, Journal Year: 2024, Volume and Issue: 146, P. 113881 - 113881
Published: Dec. 24, 2024
Language: Английский
International Immunopharmacology, Journal Year: 2025, Volume and Issue: 149, P. 114230 - 114230
Published: Feb. 7, 2025
Language: Английский
Citations
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Language: Английский
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Language: Английский
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Language: Английский
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0Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15
Published: July 17, 2024
Graphical Abstract This review seeks to offer a comprehensive look at how salidroside impacts gut microbiota and its potential therapeutic role in treating atherosclerosis. (A) Salidroside has been shown have positive impact on atherosclerosis by promoting the growth of beneficial bacteria decreasing levels harmful body. (B) enhance integrity function intestinal mucosal barrier through ability suppress NF-κB p38 MAPK signaling pathways, modulate NF-κB/MAPK/JAK-STAT3 pathways increase expression antimicrobial peptides HD-5 HD-6. (C) can reduce TMAO production reducing abundance Firmicutes Proteobacteria . (D) improve SCFAs, increasing some special bacteria. (E) LPS-induced inflammation, which is associated with inhibition ROS-mediated PI3K/AKT/mTOR pathway, downregulation exosome miR-199a-5p, attenuation Notch-Hes pathway. (F) inhibit NLRP3-associated gut-coronary axis, including TLR4/MyD88/NF-κB/NLRP3 AMPK/NF-κB/NLRP3 P2X7/NF-κB/NLRP3
Language: Английский
Citations
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Published: Oct. 1, 2024
Language: Английский
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0International Immunopharmacology, Journal Year: 2024, Volume and Issue: 146, P. 113881 - 113881
Published: Dec. 24, 2024
Language: Английский
Citations
0