Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis DOI

Dipa Kusi,

Yan Sun,

Chenguang Liu

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 669, P. 125101 - 125101

Published: Dec. 19, 2024

Language: Английский

Advancing Payment Reform for Advantageous Tcm-Treated Diseases: Evaluating Health Outcomes, Costs, and Provider Perspectives DOI
Shiwen Zhang, Ying‐Ping Wang,

Xiaoyu Zhang

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0

Argatroban and Menadione exert protective effects in ultraviolet-irradiated skin inflammation: A transcriptomic analysis based on identification of iron overload related biomarkers DOI

Jiacheng Lv,

Huilin Quan,

J. Lv

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 151, P. 114334 - 114334

Published: Feb. 27, 2025

Language: Английский

Citations

0

The role and mechanism of “eight famous herbals in Zhejiang” in cancer via network pharmacology and experimental validation DOI Creative Commons

Ziheng Ni,

Hao Zhang, Fengyun Chen

et al.

Frontiers in Oncology, Journal Year: 2024, Volume and Issue: 14

Published: Nov. 15, 2024

In recent years, some components and active ingredients from the herbal formula “eight famous herbals in Zhejiang” (Zhe-Ba-Wei) have been reported to possess antitumor properties. However, there is still no systemic study on role mechanism of Zhe-Ba-Wei cancer. To systematically investigate anticancer efficacy Zhe-Ba-Wei, we first identified 17 with gene targets associated various types tumors. Second, screened these their responding multiple shared by analyzing convergence diverse tumor-specific target sites four crucial (ferulic acid, quercetin, rutin, luteolin), which were characterized 27 overlapping targets. Third, subsequently mapped onto Kyoto Encyclopedia Genes Genomes (KEGG) pathway Gene Ontology term, among total potential targets, 12 involved plasma membrane function. Fourth, investigated binding affinities between such as EGFR MET, both are well-known oncogenes cancers. Subsequently, an investigation computational ADMET properties showed that most exhibited good Finally, found three luteolin, quercetin) could inhibit proliferation non-small cell lung cancer cells decrease protein expression a concentration-dependent manner. All results shed light bioactive components, pharmacological effects, drug development utilization aiming provide useful support for its further research clinical application.

Language: Английский

Citations

0

Advances in Manganese-based nanomaterials for cancer therapy via regulating Non-Ferrous ferroptosis DOI

Dipa Kusi,

Yan Sun,

Chenguang Liu

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 669, P. 125101 - 125101

Published: Dec. 19, 2024

Language: Английский

Citations

0