Food Science & Nutrition,
Journal Year:
2024,
Volume and Issue:
12(12), P. 10716 - 10733
Published: Nov. 24, 2024
ABSTRACT
The
current
study
aims
to
prepare
a
green
extract
using
new
method
in
addition
conventional
extraction
methods
including;
methanolic
and
ultrasonic
of
Salvia
triloba
,
compare
their
phenolic
composition
utilizing
high‐performance
liquid
chromatograph
equipped
with
diode
array
detector
(HPLC‐DAD),
anti‐bacterial,
anti‐oxidant,
enzyme
inhibition
activities.
results
HPLC‐DAD
analysis
showed
that
Rosmarinic
acid
was
found
the
highest
amount
followed
by
extracts
as
169.7
±
0.51,
135.1
0.40,
28.58
0.46
μg/g
respectively.
Trans‐cinnamic
(4.40
0.09
μg/g)
exclusively
extract.
For
bioactivities,
exhibited
biofilm
against
Enterococcus
faecalis
compared
other
extracts,
while
outperformed
both
ultrasonic‐assisted
Staphylococcus
aureus
Escherichia
coli
strains
at
minimum
inhibitory
concentration.
considerable
quorum
sensing
Chromobacterium
violaceum
CV026,
no
activity
recorded
from
S.
moderate
butyrylcholinesterase
inhibition;
each
demonstrated
limited
effects
on
urease
enzyme.
Similarly,
significant
antioxidant
activity,
β‐carotene‐linoleic
assay
(IC
50
=
10.29
0.36
μg/mL),
DPPH
•
27.77
0.55
ABTS
•+
15.49
0.95
metal
chelating
57.80
CUPRAC
(assay
A
0.50
32.54
0.84
μg/mL).
Furthermore,
better
than
α‐tocopherol
(Standard
used).
potential
solvent(s)
eco‐friendly
alternative
for
extractin
compounds
evaluated
biological
activities
first
time.
Antibiotics,
Journal Year:
2024,
Volume and Issue:
13(7), P. 665 - 665
Published: July 18, 2024
In
this
research,
several
analyses
were
carried
out
on
concentrated
fractions
of
Mexican
oregano
essential
oil
(Poliomintha
longiflora
Gray)
in
order
to
determine
its
ability
inhibit
the
growth
and
motility
Escherichia
coli
(swimming),
Pseudomonas
aeruginosa
Proteus
vulgaris
(swarming);
these
Gram-negative
bacteria
associated
with
urinary
tract
infections
are
motile
due
presence
flagella,
which
is
considered
an
important
virulence
factor
that
favors
their
when
trying
reach
target
organ
cause
infection.
Also,
resistance
pattern
antibiotics
each
strain
was
determined.
The
results
showed
(8
12
tested)
for
P.
aureginosa,
while
E.
resistant
4
tested.
On
other
hand,
fractionated
caused
inhibition
a
reduction
motility,
varying
between
among
bacteria.
Fraction
major
reduction,
MBC
values
ranging
from
0.002
23.7
mg/mL.
Treatment
(F1,
F2,
F3,
F4)
reduced
by
92–81%
vulgaris,
90–83%
coli,
100–8.9%
aeruginosa.
These
demonstrated
higher
performance
lower
application
dose
high
content
Carvacrol
Thymol;
unlike
fractions,
synergy
oxygenated
monoterpenes
may
greater
antimicrobial
activity.
International Journal of Advancement in Life Sciences Research,
Journal Year:
2024,
Volume and Issue:
07(03), P. 24 - 36
Published: Jan. 1, 2024
Urinary
tract
infections
(UTIs)
are
a
pressing
global
health
concern,
exacerbated
by
the
rise
of
antibiotic-resistant
bacterial
strains.
Bioprospecting,
involving
exploration
natural
resources
for
therapeutic
potential,
offers
promising
approach
to
tackling
this
challenge.
Ethnopharmaceuticals,
traditional
medicinal
practices
and
remedies
from
indigenous
communities,
present
valuable
source
discovering
novel
bioactive
compounds.
This
review
comprehensively
evaluates
bioprospecting
ethnopharmaceuticals
their
synergistic
potential
against
UTIs.
Drawing
existing
literature,
we
analyze
diverse
range
ethnopharmaceuticals,
elucidating
mechanisms
action
experimental
evidence
supporting
interactions.
Ethno-pharmaceuticals
encompass
various
plant-based
extracts,
herbal
remedies,
healing
utilized
across
generations
manage
infections.
We
examine
scientific
efficacy
in
treating
UTIs,
clarifying
components
modes
action.
Integration
knowledge
with
modern
methodologies
is
crucial
addressing
contemporary
challenges.
By
harnessing
ethno-pharmaceuticals,
can
develop
alternative
therapies
offering
hope
improved
treatment
outcomes
amidst
antibiotic
resistance.
Food Science & Nutrition,
Journal Year:
2024,
Volume and Issue:
12(12), P. 10716 - 10733
Published: Nov. 24, 2024
ABSTRACT
The
current
study
aims
to
prepare
a
green
extract
using
new
method
in
addition
conventional
extraction
methods
including;
methanolic
and
ultrasonic
of
Salvia
triloba
,
compare
their
phenolic
composition
utilizing
high‐performance
liquid
chromatograph
equipped
with
diode
array
detector
(HPLC‐DAD),
anti‐bacterial,
anti‐oxidant,
enzyme
inhibition
activities.
results
HPLC‐DAD
analysis
showed
that
Rosmarinic
acid
was
found
the
highest
amount
followed
by
extracts
as
169.7
±
0.51,
135.1
0.40,
28.58
0.46
μg/g
respectively.
Trans‐cinnamic
(4.40
0.09
μg/g)
exclusively
extract.
For
bioactivities,
exhibited
biofilm
against
Enterococcus
faecalis
compared
other
extracts,
while
outperformed
both
ultrasonic‐assisted
Staphylococcus
aureus
Escherichia
coli
strains
at
minimum
inhibitory
concentration.
considerable
quorum
sensing
Chromobacterium
violaceum
CV026,
no
activity
recorded
from
S.
moderate
butyrylcholinesterase
inhibition;
each
demonstrated
limited
effects
on
urease
enzyme.
Similarly,
significant
antioxidant
activity,
β‐carotene‐linoleic
assay
(IC
50
=
10.29
0.36
μg/mL),
DPPH
•
27.77
0.55
ABTS
•+
15.49
0.95
metal
chelating
57.80
CUPRAC
(assay
A
0.50
32.54
0.84
μg/mL).
Furthermore,
better
than
α‐tocopherol
(Standard
used).
potential
solvent(s)
eco‐friendly
alternative
for
extractin
compounds
evaluated
biological
activities
first
time.
