Therapeutic effects of Huangqi formula (Eefooton) in chronic kidney disease: clinical research and narrative literature review DOI Creative Commons

Kuo Cheng Lu,

Shang-Lun Wu,

Tsuo-Cheng Lu

et al.

Aging, Journal Year: 2024, Volume and Issue: 16(22), P. 13627 - 13647

Published: Dec. 7, 2024

Objective: The study aimed to assess the clinical effects of employing Huangqi formula (Eefooton; EFT) for chronic kidney disease (CKD) treatment. A narrative literature review was undertaken elucidate specific ingredients EFT and their potential impact on renal health. Methods: retrospective observational investigated treatment in outpatients with stable CKD (stages 3B 5) from March 2019 2021. Patients received 20 mL thrice daily 6 months, along standard Control groups were matched cohort. Regular assessments renal, liver functions, lipid profiles conducted. Results: Serum creatinine (Cr) eGFR levels consistently improved stage patients at each follow-up visit. At improvement Cr observed 4 5 CKD. Stage exhibited notable reductions systolic blood pressure after 3 months Remarkably, a substantial decrease HbA1C noted individuals three therapy. Additionally, saw significant reduction LDL both indicated that positive might be associated its anti-inflammatory, antioxidant, anti-fibrotic properties. Conclusions: This research demonstrated incorporating alongside enhanced function is proposed as feasible complementary patients, emphasizing importance early intervention.

Language: Английский

Fermented Codonopsis pilosula residue improved milk performance of lactating donkeys by enhancing antioxidant capacity and regulating metabolism DOI Creative Commons
Miaomiao Zhou, Fei Huang, Xinyi Du

et al.

Frontiers in Veterinary Science, Journal Year: 2024, Volume and Issue: 11

Published: Nov. 18, 2024

The fermented Codonopsis pilosula residue (FCPR) has a promoting effect on animal health, but it not been studied in livestock feed. This study investigated the effects of FCPR addition milk performance, metabolites, and blood biochemical parameters metabolites lactating donkeys. Twelve healthy multiparous Dezhou donkeys were randomly divided into two groups (with 6 each group): control group (without FCPR, C) (200 g per head day, FF). experiment lasted for 5 weeks. samples collected at end experiment. results showed that significantly increased daily yield components (protein, lactose, solids, solids-not-fat, lactoferrin) weight gain foals ( p < 0.05). A total 568 detected donkey milk, including 21 differential between FF C. Compared to C, up-regulated metabolic pathway was renin secretion In addition, concentrations urea, complement C4 (C4), antioxidant capacity (T-AOC), catalase (CAT) blood, while reducing concentration malondialdehyde (MDA) 753 serum donkeys, 86 pathways secretion, cAMP signaling pathway, regulation lipolysis adipocytes, fatty acid biosynthesis above indicated enhance performance by activating immune system, increasing capacity, improving glucose lipid metabolism. These provide foundation development utilization additives, which is beneficial production welfare.

Language: Английский

Citations

1

Therapeutic effects of Huangqi formula (Eefooton) in chronic kidney disease: clinical research and narrative literature review DOI Creative Commons

Kuo Cheng Lu,

Shang-Lun Wu,

Tsuo-Cheng Lu

et al.

Aging, Journal Year: 2024, Volume and Issue: 16(22), P. 13627 - 13647

Published: Dec. 7, 2024

Objective: The study aimed to assess the clinical effects of employing Huangqi formula (Eefooton; EFT) for chronic kidney disease (CKD) treatment. A narrative literature review was undertaken elucidate specific ingredients EFT and their potential impact on renal health. Methods: retrospective observational investigated treatment in outpatients with stable CKD (stages 3B 5) from March 2019 2021. Patients received 20 mL thrice daily 6 months, along standard Control groups were matched cohort. Regular assessments renal, liver functions, lipid profiles conducted. Results: Serum creatinine (Cr) eGFR levels consistently improved stage patients at each follow-up visit. At improvement Cr observed 4 5 CKD. Stage exhibited notable reductions systolic blood pressure after 3 months Remarkably, a substantial decrease HbA1C noted individuals three therapy. Additionally, saw significant reduction LDL both indicated that positive might be associated its anti-inflammatory, antioxidant, anti-fibrotic properties. Conclusions: This research demonstrated incorporating alongside enhanced function is proposed as feasible complementary patients, emphasizing importance early intervention.

Language: Английский

Citations

0