UPFs and Shortened Lifespans: Ultra-Processed Foods Linked to Accelerated Biological Aging; Consequences Across Human Body Systems and Implications for Associated Medical Specialties DOI Creative Commons
Nicholas A Kerna, Chibuike Eze, Okatta A. Ugochukwu

et al.

Scientia. Technology, science and society., Journal Year: 2025, Volume and Issue: 2(3), P. 13 - 36

Published: March 1, 2025

Ultra-processed foods (UPFs) are defined by their high levels of refined carbohydrates, unhealthy fats, artificial additives, and preservatives. These contribute to biological aging through mechanisms such as chronic inflammation, oxidative stress, metabolic dysfunction. Inflammation, disruptions in insulin signaling key factors the development aging-related diseases, including cardiovascular disease, diabetes, neurodegenerative disorders. Specifically, advanced glycation end-products (AGEs) epigenetic modifications significantly acceleration disrupting cellular function, promoting tissue damage, driving disease development. UPF consumption is linked cancer, gastrointestinal disorders, obstetric gynecological conditions, a range adverse effects on various body systems. Reducing intake encouraging healthier dietary patterns crucial for mitigating impact UPFs related health conditions. For individuals unable transition whole food-based diets, pharmaceutical medical interventions offer alternatives reduce UPF-related aging. A combined approach pharmacologic therapies adjustments may optimize outcomes, with ongoing research into novel treatments further enhancing strategies counteract effects. This review examines accelerating aging, which they associated potential mitigate

Language: Английский

UPFs and Shortened Lifespans: Ultra-Processed Foods Linked to Accelerated Biological Aging; Consequences Across Human Body Systems and Implications for Associated Medical Specialties DOI Creative Commons
Nicholas A Kerna, Chibuike Eze, Okatta A. Ugochukwu

et al.

Scientia. Technology, science and society., Journal Year: 2025, Volume and Issue: 2(3), P. 13 - 36

Published: March 1, 2025

Ultra-processed foods (UPFs) are defined by their high levels of refined carbohydrates, unhealthy fats, artificial additives, and preservatives. These contribute to biological aging through mechanisms such as chronic inflammation, oxidative stress, metabolic dysfunction. Inflammation, disruptions in insulin signaling key factors the development aging-related diseases, including cardiovascular disease, diabetes, neurodegenerative disorders. Specifically, advanced glycation end-products (AGEs) epigenetic modifications significantly acceleration disrupting cellular function, promoting tissue damage, driving disease development. UPF consumption is linked cancer, gastrointestinal disorders, obstetric gynecological conditions, a range adverse effects on various body systems. Reducing intake encouraging healthier dietary patterns crucial for mitigating impact UPFs related health conditions. For individuals unable transition whole food-based diets, pharmaceutical medical interventions offer alternatives reduce UPF-related aging. A combined approach pharmacologic therapies adjustments may optimize outcomes, with ongoing research into novel treatments further enhancing strategies counteract effects. This review examines accelerating aging, which they associated potential mitigate

Language: Английский

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