Safety evaluation of ILaris: a real-world analysis of adverse events based on the FAERS Database DOI
Xun Yi, S. L. Wu, He He

et al.

Expert Opinion on Drug Safety, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: Feb. 22, 2025

There is a lack of real-world studies on the safety Ilaris in large populations. The purpose this study was to investigate adverse events (AEs) associated with using data from FDA Adverse Event Reporting System (FAERS) database guide clinical use. We evaluated retrospectively extracted reports AEs FAERS between first quarter 2009 and second 2024. presence significant association assessed by disproportionality analyses including ROR,PRR,BCPNN,MGPS. After evaluating 14,691,170 data, 7968 ILaris-associated were obtained after removing duplicates unspecified sex items. A number finalized through study, Common Pyrexia, Condition Aggravated, Influenza, unexpected signals not listed drug insert, such as Pulmonary Thrombosis, Hepatomegaly, Blood Lactate Dehydrogenase Increased, Splenomegaly, Appendicitis. induced involving 27 system organ classes (SOCs). gender differences signaling Ilaris. It critical for healthcare professionals closely monitor patients symptoms (such pulmonary thrombosis, Appendicitis) other during treatment.

Language: Английский

Safety evaluation of ILaris: a real-world analysis of adverse events based on the FAERS Database DOI
Xun Yi, S. L. Wu, He He

et al.

Expert Opinion on Drug Safety, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 13

Published: Feb. 22, 2025

There is a lack of real-world studies on the safety Ilaris in large populations. The purpose this study was to investigate adverse events (AEs) associated with using data from FDA Adverse Event Reporting System (FAERS) database guide clinical use. We evaluated retrospectively extracted reports AEs FAERS between first quarter 2009 and second 2024. presence significant association assessed by disproportionality analyses including ROR,PRR,BCPNN,MGPS. After evaluating 14,691,170 data, 7968 ILaris-associated were obtained after removing duplicates unspecified sex items. A number finalized through study, Common Pyrexia, Condition Aggravated, Influenza, unexpected signals not listed drug insert, such as Pulmonary Thrombosis, Hepatomegaly, Blood Lactate Dehydrogenase Increased, Splenomegaly, Appendicitis. induced involving 27 system organ classes (SOCs). gender differences signaling Ilaris. It critical for healthcare professionals closely monitor patients symptoms (such pulmonary thrombosis, Appendicitis) other during treatment.

Language: Английский

Citations

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