Autonomic Function and Baroreflex Control in COVID-19 Patients Admitted to the Intensive Care Unit DOI Open Access
Francesca Gelpi, Maddalena Alessandra Wu, Vlasta Bari

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(8), P. 2228 - 2228

Published: April 12, 2024

Background: Autonomic function and baroreflex control might influence the survival rate of coronavirus disease 2019 (COVID-19) patients admitted to intensive care unit (ICU) compared respiratory failure without COVID-19 (non-COVID-19). This study describes physiological mechanisms in critically ill ICU comparison non-COVID-19 individuals with aim improving stratification mortality risk. Methods: We evaluated autonomic markers extracted from heart period (HP) systolic arterial pressure (SAP) variability acquired at rest supine position (REST) during a modified head-up tilt (MHUT) 17 (age: 63 ± 10 years, 14 men) 33 60 12 23 their stays. Patients were categorized as survivors (SURVs) or non-survivors (non-SURVs). Results: found that populations exhibited similar vagal sympathetic markers; however, featured smaller sensitivity an unexpected reduction HP-SAP association MHUT group. Nevertheless, none functions could distinguish SURVs non-SURVs either population. Conclusions: concluded more preserved individuals, even though this information is ineffective stratifying

Language: Английский

Instrumental Evaluation of COVID-19 Related Dysautonomia in Non-Critically-Ill Patients: An Observational, Cross-Sectional Study DOI Open Access
Simone Bellavia, Irene Scala, Marco Luigetti

et al.

Journal of Clinical Medicine, Journal Year: 2021, Volume and Issue: 10(24), P. 5861 - 5861

Published: Dec. 14, 2021

Coronavirus disease-19 (COVID-19) is a predominantly respiratory syndrome. Growing reports about SARS-CoV-2 neurological involvement, including autonomic dysfunction (AD), have been reported, mostly in critically-ill patients, or the long-COVID In this observational, cross-sectional study, we investigated prevalence of AD 20 non-critically-ill COVID-19 patients (COVID+ group) acute phase disease through composite instrumental evaluation consisting Sudoscan, automated pupillometry, heart rate variability (HRV), and pulse transit time (PTT). All parameters were compared to control group healthy volunteers (COVID− group). COVID+ presented higher values pupillary dilatation velocities, baseline pupil diameter than COVID− subjects. Moreover, incidence feet sudomotor group. No significant differences emerged HRV PTT between groups. study observed occurrence early stage disease.

Language: Английский

Citations

19

Alternation of the Autonomic Nervous System Is Associated With Pulmonary Sequelae in Patients With COVID-19 After Six Months of Discharge DOI Creative Commons
Tao Bai,

Dan Zhou,

Feierkaiti Yushanjiang

et al.

Frontiers in Physiology, Journal Year: 2022, Volume and Issue: 12

Published: Jan. 21, 2022

Previous studies suggest that autonomic dysfunction is associated with disease severity in acute phase patients coronavirus 2019 (COVID-19). However, the association between and pulmonary sequelae COVID-19 unknown. We conducted a prospective study to investigate discharged for 6 months. included 40 eligible participants collected following indicators: heart rate variability (HRV), function tests (PFTs), lung X-ray computed tomography (CT), routine blood parameters, liver lymphocyte subsets. found at months post-discharge, HRV still had tight correlation fibrosis. There was significant difference without diffusion dysfunction, but did not differ or ventilatory dysfunction. Diffusion fibrosis were tightly associated, index changes same trend as of They lower standard deviation NN intervals (SDNN), average (SDANN), triangular index, higher ratio LF HF power (LF/HF). In addition, WBC, neutrophils, CD4/CD8 correlated HRV. concluded closely immune mechanisms may potentially contribute this process.

Language: Английский

Citations

13

Autonomic Function Recovery and Physical Activity Levels in Post-COVID-19 Young Adults after Immunization: An Observational Follow-Up Case-Control Study DOI Open Access
Ana Paula Coelho Figueira Freire, Shaan Amin, Fábio Santos Lira

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(3), P. 2251 - 2251

Published: Jan. 27, 2023

Coronavirus disease 2019 (COVID-19) has detrimental multi-system consequences. Symptoms may appear during the acute phase of infection, but literature on long-term recovery young adults after mild to moderate infection is lacking. Heart rate variability (HRV) allows for observation autonomic nervous system (ANS) modulation post-SARS-CoV-2 infection. Since physical activity (PA) can help improve ANS modulation, investigating factors that influence HRV outcomes COVID-19 essential advancements in care and intervention strategies. Clinicians use this research aid development non-medication interventions. At baseline, 18 control (CT) 20 post-COVID-19 (PCOV) participants were observed where general anamnesis was performed, followed by PA assessment. Thus, 10 CT 7 PCOV subjects returned follow-up (FU) evaluation 6 weeks complete immunization (two doses) assessments repeated. Over period, a decrease sympathetic (SNS) (mean heart rate: p = 0.0024, CI -24.67--3.26; SNS index: 0.0068, -2.50--0.32) increase parasympathetic (PNS) RR: 0.0097, 33.72-225.51; PNS 0.0091, -0.20-1.47) observed. follow-up, not different between groups (p > 0.05). Additionally, no differences moments groups. This study provides evidence SARS-CoV-2 insult over independent changes PA.

Language: Английский

Citations

7

Vertebral Subluxation and Systems Biology: An Integrative Review Exploring the Salutogenic Influence of Chiropractic Care on the Neuroendocrine-Immune System DOI Open Access

A L Haas,

Jonathan Chung,

Christopher Kent

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: March 15, 2024

In this paper we synthesize an expansive body of literature examining the multifaceted influence chiropractic care on processes within and modulators neuroendocrine-immune (NEI) system, for purpose generating inductive hypothesis regarding potential impacts integrated physiology. Taking a broad, interdisciplinary, integrative view two decades research-documented outcomes care, inclusive reports ranging from systematic meta-analysis randomized observational trials to case cohort studies, review encapsulates rigorous analysis research suggests appropriateness more perspective impact systemic A novel salutogenic, health-promoting effects adjustment is presented, focused improvement physical indicators well-being adaptability such as blood pressure, heart rate variability, sleep, benefits that may be facilitated through multiple neurologically mediated pathways. Our findings support biological plausibility complex intervention not limited simple neuromusculoskeletal open new avenues future research, specifically exploration mapping precise neural pathways networks influenced by adjustment.

Language: Английский

Citations

2

Autonomic Function and Baroreflex Control in COVID-19 Patients Admitted to the Intensive Care Unit DOI Open Access
Francesca Gelpi, Maddalena Alessandra Wu, Vlasta Bari

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(8), P. 2228 - 2228

Published: April 12, 2024

Background: Autonomic function and baroreflex control might influence the survival rate of coronavirus disease 2019 (COVID-19) patients admitted to intensive care unit (ICU) compared respiratory failure without COVID-19 (non-COVID-19). This study describes physiological mechanisms in critically ill ICU comparison non-COVID-19 individuals with aim improving stratification mortality risk. Methods: We evaluated autonomic markers extracted from heart period (HP) systolic arterial pressure (SAP) variability acquired at rest supine position (REST) during a modified head-up tilt (MHUT) 17 (age: 63 ± 10 years, 14 men) 33 60 12 23 their stays. Patients were categorized as survivors (SURVs) or non-survivors (non-SURVs). Results: found that populations exhibited similar vagal sympathetic markers; however, featured smaller sensitivity an unexpected reduction HP-SAP association MHUT group. Nevertheless, none functions could distinguish SURVs non-SURVs either population. Conclusions: concluded more preserved individuals, even though this information is ineffective stratifying

Language: Английский

Citations

2