The Yale Journal of Biology and Medicine,
Journal Year:
2024,
Volume and Issue:
97(2), P. 225 - 238
Published: June 28, 2024
Joint
hypermobility
syndromes,
particularly
chronic
pain
associated
with
this
condition,
including
Hypermobile
Ehlers-Danlos
Syndrome
(hEDS)
and
Hypermobility
Spectrum
Disorders
(HSD),
present
diagnostic
challenges
due
to
their
multifactorial
origins
remain
poorly
understood
from
biomechanical
genomic-molecular
perspectives.
Recent
guidelines
have
differentiated
hEDS,
HSD,
benign
joint
hypermobility,
providing
a
more
objective
framework.
However,
incorrect
diagnoses
underdiagnoses
persist,
leading
prolonged
journeys
for
affected
individuals.
Musculoskeletal
manifestations,
pain,
dysautonomia,
gastrointestinal
symptoms
illustrate
the
impact
of
these
conditions,
affecting
both
physical
emotional
well-being
Infrared
thermography
(IRT)
emerges
as
promising
tool
assessment,
especially
in
detecting
inflammatory
processes.
Thermal
distribution
patterns
offer
valuable
insights
into
dysfunctions,
although
direct
correlation
between
inflammation
remains
challenging.
The
prevalence
neuropathies
among
hypermobile
individuals
accentuates
discordance
perception
thermographic
findings,
further
complicating
diagnosis
management.
Despite
its
potential,
clinical
integration
IRT
faces
challenges,
conflicting
evidence
hindering
adoption.
studies
demonstrate
temperature
disparities
healthy
diseased
joints,
under
dynamic
thermography,
suggesting
potential
utility
practice.
Future
research
focused
on
refining
criteria
elucidating
underlying
mechanisms
syndromes
will
be
essential
improve
accuracy
enhance
patient
care
complex
multidimensional
context.
Wound Repair and Regeneration,
Journal Year:
2025,
Volume and Issue:
33(1)
Published: Jan. 1, 2025
Abstract
Pressure
injuries
in
critically
ill
patients
present
a
significant
healthcare
burden.
Traditional
methods,
such
as
the
Braden
score,
assess
risk
of
developing
pressure
by
evaluating
factors
like
sensory
perception,
moisture
and
mobility.
In
contrast,
thermographic
imaging,
which
measures
variations
skin
temperature,
offers
promising
tool
for
not
only
assessing
but
also
enabling
earlier
identification
injuries.
This
study
assessed
imaging's
ability
to
detect
existing
evolving
surgical
intensive
care
unit
(SICU)
compared
its
accuracy
with
score.
Among
465
patients,
76
underwent
evaluations
sacrum
and/or
heel.
Of
25
at
admission,
23
had
abnormal
scores.
Fifteen
patient
developed
during
SICU
admission.
Logistic
regression
showed
that
scores
significantly
increased
likelihood
detecting
both
new
injuries,
while
score
was
predictor.
Thermographic
imaging
appears
be
superior
predictor
offering
detection
potentially
improving
outcomes
reducing
costs.
BMC Cancer,
Journal Year:
2025,
Volume and Issue:
25(1)
Published: Feb. 20, 2025
Predicting
radiation
dermatitis
(RD),
a
common
radiotherapy
toxicity,
is
essential
for
clinical
decision-making
regarding
toxicity
management.
This
prospective
study
aimed
to
develop
and
validate
machine-learning
model
predict
the
occurrence
of
grade
≥
2
RD
using
thermal
imaging
in
early
stages
head
neck
cancer.
Thermal
images
skin
surfaces
were
acquired
weekly
during
radiotherapy.
A
total
202
used
calculate
difference
map
temperature
analyze
extract
features.
Changes
features
treatment
assessed
two
groups,
≤
1
RD,
classified
according
Common
Terminology
Criteria
Adverse
Events
(CTCAE)
guidelines.
Feature
importance
analysis
was
performed
select
correlated
with
RD.
predictive
developed
machine
learning
algorithm
cross-validated.
Area
under
receiver-operating
characteristic
curve
(AUC),
precision,
sensitivity
as
evaluation
metrics.
Of
images,
54
taken
before
model.
radiomics
related
homogeneity
image
texture
selected
input
The
gradient
boosting
decision
tree
showed
an
AUC
0.84,
precision
0.70,
0.75
models
trained
dose
<
10
Gy.
support
vector
achieved
mean
0.71,
0.68,
0.70
predicting
obtained
range
10-20
from
patients
undergoing
cancer
can
be
predictor
may
aid
management
acute
However,
our
results
should
interpreted
caution,
given
limitations
this
study.
Frontiers in Veterinary Science,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 24, 2025
Thermal
imaging
has
been
used
in
animal
models
to
non-invasively
detect
surface
temperature
changes
after
several
pathologic
and
surgical
processes.
Infrared
thermography
(IRT)
identifies
increases
or
decreases
radiated
heat
according
blood
circulation
microcirculation.
The
present
review
aims
discuss
the
most
relevant
aspects
of
IRT
applied
biomedical
research
as
a
noninvasive
technique
models,
highlighting
its
importance
clinical
setting
for
translational
medicine.
provides
an
alternative
evaluate
vascular
anomalies
where
flow
is
interrupted.
In
processes
such
anastomosis
reconstructive
techniques
(e.g.,
grafts
flaps),
thermal
can
assess
viability
tissues.
burn
injuries,
predict
identify
areas
ischemia-necrosis
inflammation.
Nonetheless,
although
potential
use
both
human
patients,
other
encouraged.
Journal of Biophotonics,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 25, 2025
This
study
investigated
the
use
of
thermography
as
a
non-invasive
tool
to
monitor
physiological
responses
mechanical
workload
in
Division-I
female
soccer
players.
A
total
29
student-athletes
(age:
19.8
±
1.1
years)
participated,
with
thermographic
imaging
conducted
throughout
training
across
competitive
season.
8106
observations
were
analyzed,
revealing
weak
but
significant
negative
correlation
between
player
load
(TPL)
and
changes
body
region
temperature
(∆t)
(βTPL
=
-0.00047;
p
<
0.0001).
For
every
one
unit
increase
TPL,
skin
decreased
by
0.00047°C
on
average.
Similar
patterns
observed
high-minute
players
-0.0046;
0.0001)
when
excluding
goalkeepers
-0.00027,
0.001).
Interestingly,
cooler
temperatures
linked
higher
workloads
field
players,
contrasting
previous
research.
These
findings
suggest
may
reflect
external
workload,
position-specific
demands
requiring
tailored
metrics
for
accurate
monitoring.
International Wound Journal,
Journal Year:
2023,
Volume and Issue:
21(3)
Published: Nov. 13, 2023
Abstract
The
emerging
evidence
has
indicated
the
role
of
microRNAs
(miRNA)
in
various
physiological
or
pathological
processes.
Also,
documents
have
suggested
that
exercise,
by
affecting
miRNA
regulation,
may
enhance
burn
wound
healing.
current
study
aims
to
systematically
review
exercise
regulating
miRNAs
related
healing
provide
potential
therapeutic
targets.
A
comprehensive,
systematic
search
was
performed
different
international
electronic
databases,
such
as
Embase,
PubMed
and
Google
Scholar
engine,
Science
Direct,
ProQuest
Ovid
using
keywords
extracted
from
Medical
Subject
Headings
2010
September
2023.
keywords,
including
‘exercise’
AND
‘burn
wound’
‘microRNA’
finally,
six
cases
were
achieved.
Evidence
promote
wounds
certain
miRNAs.
Studies
found
regulates
expression
mir‐155,
miR‐21,
let‐7a,
miR‐146a,
miR‐122
mir‐210
tissue,
which
regulate
inflammation
angiogenesis.
These
findings
suggest
play
a
positive
effect
on
However,
further
research
is
needed
understand
mechanisms
involved
fully.
Sensors,
Journal Year:
2024,
Volume and Issue:
24(14), P. 4457 - 4457
Published: July 10, 2024
This
review
aims
to
explore
recent
advancements
in
optical
imaging
techniques
for
monitoring
the
viability
of
Deep
Inferior
Epigastric
Perforator
(DIEP)
flap
reconstruction.
The
objectives
include
highlighting
principles,
applications,
and
clinical
utility
modalities
such
as
near-infrared
spectroscopy
(NIRS),
indocyanine
green
(ICG)
fluorescence
angiography,
laser
speckle
contrast
(LSCI),
hyperspectral
(HSI),
dynamic
infrared
thermography
(DIRT),
short-wave
(SWIR)
assessing
tissue
perfusion
oxygenation.
Additionally,
this
discuss
potential
these
enhancing
surgical
outcomes
by
enabling
timely
intervention
cases
compromised
perfusion.
Proceedings of the National Academy of Sciences,
Journal Year:
2024,
Volume and Issue:
121(49)
Published: Nov. 26, 2024
Continuous
monitoring
and
closed-loop
therapy
of
soft
wound
tissues
is
particular
interest
in
biomedical
research
clinical
practices.
An
important
focus
on
the
development
implantable
bioelectronics
that
can
measure
time-dependent
temperature
distribution
related
to
localized
inflammation
over
large
areas
offer
situ
treatment.
Existing
approaches
such
as
thermometers/thermocouples
provide
limited
spatial
resolution,
inapplicable
a
wearable/implantable
format.
Here,
we
report
conformal,
scalable
device
package
integrates
flexible
amorphous
silicon–based
sensor
array
drug-loaded
hydrogel
for
healing
process.
This
system
enable
mapping
at
submillimeter
resolution
high
sensitivity
0.1
°C,
dynamically
localizing
regions
associated
with
change,
automatically
followed
heat-triggered
drug
delivery
from
triggered
by
wearable
infrared
light-emitting-diodes.
We
establish
operational
principles
experimentally
computationally
evaluate
functionalities
wide
range
targets
including
live
animal
models
human
subjects.
As
an
example
medical
utility,
this
yield
monitoring/treatments
tracking
rats,
designs
be
integrated
automated
wireless
control.
These
findings
create
broad
utilities
these
platforms
diagnosis
advanced
healthcare.